No Difference Between Latiglutenase and Placebo in Reducing Villous Atrophy or Improving Symptoms in Patients With Symptomatic Celiac Disease

Autor: Ansari, S., Ayub, K., Basile, A., Behrend, C., Bercik, P., Bressler, B., Byrnes, V., Chandan, V.S., Cheekati, V., Chipps, B., Coates, A., Collatrella, A., Condemi, J., Corder, C., Corren, J., Curtis, C., DeMeo, M., Desta, T., Devereaux, C., DiMarino, A., DuPree, M., Ennis, C., Fedorak, R., Fogel, R., Freeman, S., Freilich, B., Friedenberg, K., Geenen, D., Gill, K., Goldsobel, A., Goldstein, J., Goldstein, M., Gordon, G., Hardi, R., Harris, L., Holmes, R., Jagarlamundi, K., James, G., Kaplan, M., Kirstein, J., Knoll, A., Kotfila, R., Krause, R., Kravitz, A., Kreines, M., Lähdeaho, M.L., Lamet, M., Laskin, K., Lebwohl, B., Leffler, D., Lewis, S., Liakos, S., Lundin, K., Marks, K., Merkes, K., Minton, S., Moussa, S., Narayen, V., Nehra, V., Newton, E., Nyberg, A., Oosthuizen, J., Otrok, T., Patel, D., Pepin, C., Phillips, R., Pyle, G., Reichelderfer, M., Reid, B., Ritter, T., Saini, S., Sanders, D., Schulman, M., Semrad, C., Shah, S., Stockwell, D., Strout, C., Suez, D., Tatum, H., Torbenson, M.S., Turner, M., Varunok, P., Vazquez-Roque, M., Vento, A., Welton, T., Wohlman, R., Wood, M., Woods, S., Yousef, K., Murray, Joseph A., Kelly, Ciarán P., Green, Peter H.R., Marcantonio, Annette, Wu, Tsung-Teh, Mäki, Markku, Adelman, Daniel C.

Publikováno v: In Gastroenterology March 2017 152(4):787-798

Vedolizumab versus Adalimumab for Moderate-to-Severe Ulcerative Colitis

Autor: Sands BE1, Peyrin-Biroulet L1, Loftus EV Jr1, Danese S1, Colombel JF1, Törüner M1, Jonaitis L1, Abhyankar B1, Chen J1, Rogers R1, Lirio RA1, Bornstein JD1, Schreiber S1, Calvo S, Gimenez E, Resk JH, Tron EP, Al-Ansari M, Andrews J, Bampton P, Debinski H, Hendy P, Holtmann G, Leong R, Moore G, Hindryckx P, Barac T, Draganova R, Kotzev I, Marinova I, Markov M, Mihaylov Y, Pavlov D, Penkova M, Petrov A, Spassova Z, Stoyanova D, Velev E, Vladimirov B, Yanev F, Axler J, Fedorak R, Fowler S Jr, Halder S, Jairath V, Ponich T, Wong K, Baez E, Ricardo J, Velasquez M, Banic M, Bogadi I, Borzan V, Zgrablic JC, Duvnjak M, Gusej M, Krznaric Z, Cechova I, Hala T, Janu L, Kohout P, Lukas M, Machkova M, Matous J, Ulbrych J, Vanasek T, Klinge L, Rannem T, Theede K, Borissova J, Kull K, Amil M, Bouhnik Y, Gilleta C, Fumery M, Grimaud JC, Hebuterne X, Laharie D, Moreau J, Peyrin-Biroulet L, Roblin X, Baumgart D, Buening C, Dinter J, Gauss A, Kuehbacher T, Fareed Rahman K, Schiefke I, Schreiber S, Von Amim U, Zeuzem S, Leung WK, Kin Kong Li M, Altorjay I, Bene L, Lakatos P, Molnar T, Salamon A, Schnabel R, Tulassay Z, Avni Y, Barkay O, Fishman S, Goldin E, Keret D, Lahat-Zok A, Melzer E, Naftali T, Nimer A, Ovadia B, Zittan E, Andriulli A, Cappello M, Castiglione F, Danese S, Fries W, Gionchetti P, Kohn A, Maconi G, Santino M, Savarino E, Privitera A, Romano M, Vecchi M, Villa E, Cheon JH, Han DS, Jang BI, Jeen YT, Kim JS, Kim SK, Kim HJ, Kim Y, Lee KM, Lee BI, Park DI, Park YS, Song GA, Ye BD, Pokrotnieks J, Tolmanis I, Denapiene G, Kancauskas A, Jakovlevaite V, Jonaitis L, Cruz Palacios A, Larriva de Los Reyes E, Asela Lujano Nicolas L, Mendoza Fuerte E, D'Haens G, Pierik M, Van Der Woude J, Adrych K, Danilkiewicz WC, Gawdis-Wojnarska B, Hartleb M, Karczewski M, Kierkus J, Malecka-Panas E, Petryka R, Piotrowski W, Regula J, Romatowski J, Rozciecha J, Rydzewska G, Smolinski P, Walczak P, Walczak M, Wozniak-Stolarska B, Cotter J, Lopes L, Portela F, Rodrigues Carvalho J, Simona Gheorghe L, Goldis AE, Mateescu RB, Abdulkhakov R, Agafyina A, Alexeeva O, Alikhanov B, Bunkova E, Dvorkin M, Gubonina I, Kashnikov V, Livzan M, Osipenko M, Parfenov A, Pershko A, Pesegova M, Rafalskiy V, Reshetko O, Simanenkov V, Tsybulko S, Valuyskikh E, Yakovlev A, Cvetkovic M, Damjanov D, Djuranovic S, Dugalic P, Nagorni A, Svorcan P, Zdravkovic Petrovic N, Bunganic I, Gregus M, Hlavaty T, Horvath F, Domenech Morral E, Jover Martinez R, Mendoza MIV, Shieh MJ, Wei CC, Altintas E, Atug O, Gonen C, Hamzaoglu H, Hulagu S, Toruner M, Chopey I, Danyliuk S, Datsenko O, Golovchenko N, Golovchenko O, Hospodarskyy I, Ivanov V, Klymenko V, Levchenko O, Lizogub V, Mostovoy Y, Oliinyk O, Polianskyi I, Pyrohovskyi V, Shevchuk S, Ursol G, Vdovychenko V, Vyshyvanyuk V, Beales I, Brookes M, Nwokolo C, Winter J, Aggarwal A, Aguilar H, Alnoah Z, Arce-Nunez E, Arimie C, Arterburn J, Baum C, Bellaguarda E, Bock B, Boone T, Callahan N, Chapman J, Chen S, Chiorean M, Coates A, Connor M, Dellon S, Dryden G, Du Vall G, Flores L, Fogel R, Frias J, Ginsburg P, Greenberg E, Grunkemeier D, Hellstern P, Herfarth H, Hoffman B, Horst S, Idarraga S, Iskandar H, Jain R, Jenkins E, Kaufman B, Khaleq A, Khan A, Khurana S, Lake J, Leavitt J, Leman B, Lewis D, Lindenberg D, Loftus EV, Korman L, Martin J, McCullough M, McNair A, Mehta N, Mutlu E, Narayen V, Paoli-Bruno J, Perez N, Phillips R, Raijman I, Ramirez-Vega R, Randall C, Rinesmith S, Ritter T, Safdi A, Saltzman M, Sands B, Seminerio J, Schulman M, Sedghi S, Shafran I, Shankar M, Silvers D, Soloman N, Tatum H, Tepper R, Tiongco F, Valdes M, Weber J, Zhang C.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3730::7d5fd2ab3facc13307e74c0e56bd2336
http://hdl.handle.net/11588/780656

Vedolizumab as Induction and Maintenance Therapy for Crohn's Disease

Autor: Sandborn, Wj, Feagan, Bg, Rutgeerts, P, Hanauer, S, Colombel, Jf, Sands, Be, Lukas, M, Fedorak, Rn, Lee, S, Bressler, B, Fox, I, Rosario, M, Sankoh, S, Xu, J, Stephens, K, Milch, C, Parikh, A, Bampton P, GEMINI 2 Study G. r. o. u. p., Borody, T, Chung, A, Debinski, H, Florin, T, Hetzel, D, Jakobovits, S, Lawrance, I, Leong, R, Macrae, F, Mitchell, B, Moore, G, Pavli, P, Samuel, D, Weltman, M, Haas, T, Reinisch, W, Vogel, W, Baert, F, De Maeyer, M, De Vos, M, Dewit, O, D'Haens, G, Louis, E, Muls, V, Van Assche, G, Krastev, Z, Nikolovska, D, Petrov, P, Petrov, A, Stoinov, S, Tchernev, K, Vasileva, G, Aumais, G, Axler, J, Bailey, R, Bernstein, C, Bitton, A, Bourdages, R, Cohen, A, Devroede, G, Dhalla, S, Feagan, B, Fedorak, R, Green, D, Greenberg, G, Jones, J, Larkai, E, Macintosh, D, Panaccione, R, Ponich, T, Singh, R, Sy, R, Wiesinger, H, Albin, A, Douda, L, Horny, I, Stehlik, J, Stuksa, J, Volfova, M, Vyhnalek, P, Zadorova, Z, Andersen, V, Bendtsen, F, Fallingborg, J, Rannem, T, Maelt, A, Margus, B, Salupere, R, Allez, M, Des Varennes SB, Desreumaux, P, Dupas, Jl, Grimaud, Jc, Hebuterne, X, Lerebours, E, Picon, L, Zerbib, F, Aldinger, V, Baumgart, D, Buening, C, Dollinger, M, Hoffmann, P, Howaldt, S, Klaus, J, Konturek, Jw, Krummenerl, T, Malfertheiner, P, Schmidt, W, Schreiber, S, Seidler, U, Stallmach, A, Stremmel, W, Zeitz, M, Mantzaris, G, Triantafyllou, K, Ng, C, Bene, L, Fazekas, I, Fejes, R, Gall, J, Horvat, G, Hunyady, B, Salamon, A, Toth, T, Tulassay, Z, Varga, E, Varga, M, Varga Szabo, L, Vincze, A, Oddsson, E, Örvar, K, Ahuja, V, Amarapurkar, D, Chandra, A, Koshy, A, Krishna, P, Ramakrishna, K, Reddy, N, Thorat, V, Patchett, S, Ryan, B, Ben Horin, S, Fishman, S, Lavy, A, Rachmilewitz, D, Ardizzone, S, Corazziari, E, Danese, S, Fries, Walter, Gasbarrini, A, Kohn, A, Sturniolo, Gc, Danilans, A, George, Am, Hilmi, In, Engels, Lg, Ponsioen, Cy, van der Woude CJ, Gearry, R, Haines, M, Schultz, M, Wallace, I, Wyeth, J, Florholmen, J, Jahnsen, J, Lygren, I, Röseth, A, Ciecko Michalska, I, Gonciarz, M, Horynski, M, Huk, J, Jamrozik Kruk, Z, Janke, A, Klupinska, G, Marecik, J, Paradowski, L, Rudzinski, J, Rydzewska, G, Han, Ds, Hong, Sp, Kim, Hj, Kim, Js, Kim, Ko, Kim, Yh, Yang, Sk, Gheorghe, Ls, Voiosu, Rm, Alexeeva, O, Baranovsky, A, Bunkova, E, Burnevich, E, Dolgikh, O, Grinevich, V, Lakhin, A, Tarabar, D, Ling, Kl, Bunganic, I, Cernok, S, Gregus, M, Coetzer, T, Grundling, H, Moola, Sa, Wright, Jp, Ziady, C, Bermejo, F, Calvet, X, Herrerias, Jm, Perez Calle JL, Perez Gisbert, J, Hertervig, E, Karlen, P, Michetti, P, Rogler, G, Seibold, F, Wu, Dc, Atug, O, Kurdas, Oo, Datsenko, O, Dorofyeyev, A, Dudar, L, Golovchenko, O, Klyarits'Ka, I, Skrypnyk, I, Hawthorne, Ab, Middleton, S, Abreu, M, Bala, N, Becker, S, Behm, B, Braun, R, Bukhari, M, Chen, S, Coates, A, Dar, S, Dassopoulos, T, De Villiers, W, Desautels, S, Desta, T, Dimitroff, J, Dryden, G, Duvall, A, Farraye, F, Fein, S, Liu, Bf, Gatof, D, Geenen, D, Ginsburg, P, Glombicki, A, Glover, S, Gordon, G, Grisolano, S, Hanson, J, Hardi, R, Hoffman, B, Isaacs, K, Kim, C, Koval, G, Lashner, B, Lawitz, E, Leman, B, Levine, J, Loftus, E, Mahadevan, U, Mannon, P, Marcet, J, Matsuyama, R, Matusow, G, Mccabe, R, Mirkin, K, Murphy, M, Mushahwar, A, Mutlu, E, Nagrani, M, Nguyen, D, Nichols, M, Nieves Ramirez, A, Oubre, B, Pace, S, Pandak, W, Perera, L, Quadri, A, Quallich, L, Rajapakse, R, Randall, C, Regueiro, M, Safdi, A, Sandborn, W, Sands, B, Saubermann, L, Scherl, E, Schwartz, D, Sedghi, S, Shafran, I, Shepard, R, Siegel, C, Stein, L, Tatum, H, Triebling, A, Vasudeva, R, Winston, B, Wolf, D, Younes, Z, Jewell, D, Mahon, J, Rothstein, R, Snydman, D, Massaro, J, Clifford, D, Berger, J, Major, E, Provenzale, J, Lev, M.

Publikováno v: Sandborn, W J, Feagan, B G, Rutgeerts, P, Hanauer, S, Colombel, J-F, Sands, B E, Lukas, M, Fedorak, R N, Lee, S, Bressler, B, Fox, I, Rosario, M, Sankoh, S, Xu, J, Stephens, K, Milch, C, Parikh, A, GEMINI 2 Study Group & Andersen, V 2013, ' Vedolizumab as induction and maintenance therapy for Crohn's disease ', The New England Journal of Medicine, vol. 369, no. 8, pp. 711-721 . https://doi.org/10.1056/NEJMoa1215739
New England Journal of Medicine, vol. 369, no. 8, pp. 711-721
New England Journal of Medicine, 369(8), 711-721. Massachussetts Medical Society

BACKGROUND: The efficacy of vedolizumab, an α4β7 integrin antibody, in Crohn's disease is unknown. METHODS: In an integrated study with separate induction and maintenance trials, we assessed intravenous vedolizumab therapy (300 mg) in adults with a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf374318adf97600bd8e435e89470ea7
https://doi.org/10.1056/nejmoa1215739

Vedolizumab as induction and maintenance therapy for ulcerative colitis

Autor: Feagan, Bg, Rutgeerts, P, Sands, Be, Hanauer, S, Colombel, Jf, Sandborn, Wj, Van Assche, G, Axler, J, Kim, Hj, Danese, S, Fox, I, Milch, C, Sankoh, S, Wyant, T, Xu, J, Parikh, A, Bampton P, GEMINI 1 Study G. r. o. u. p., Chung, A, Debinski, H, Florin, T, Hetzel, D, Kronborg, I, Lawrance, I, Leong, R, Macrae, F, Moore, G, Pavli, P, Radford Smith, G, Weltman, M, Haas, T, Reinisch, W, Stockenhuber, F, Vogel, W, De Maeyer, M, De Vos, M, D'Haens, G, Louis, E, Muls, V, Petrov, P, Aumais, G, Bitton, A, Bourdages, R, Bressler, B, Cohen, A, Fedorak, R, Greenberg, G, Jones, J, Kutcher, W, Macintosh, D, Ponich, T, Singh, R, Steinhart, H, Sy, R, Douda, L, Lukas, M, Samek, M, Vyhnalek, P, Woznica, V, Zadorova, Z, Andersen, V, Rannem, T, Staun, M, Maelt, A, Margus, B, Bonaz, B, Coffin, B, Desreumaux, P, Laharie, D, Reimund, Jm, Karaus, M, Pace, A, Ross, M, Schmidt, W, Witthoeft, T, Zeitz, M, Karamanolis, D, Mantzaris, G, Maris, T, Ng, C, Gall, J, Hunyady, B, Szepes, A, Toth, T, Vincze, A, Oddsson, E, Jósefsspktali, Kö, Ahuja, V, Amarapurkar, D, Goenka, M, Habeeb, Ma, Jalihal, U, Kalambe, B, Koshy, A, Kumar, R, Prasad, V, Reddy, N, Sekar, T, Shankar, R, Tantry, V, Ryan, B, Avni, Y, Ben Horin, S, Ardizzone, S, Armuzzi, A, Corazziari, E, Fries, Walter, Kohn, A, Lisova, D, George, Am, Hilmi, In, Bhaskaran, Sk, Soon, Sy, Engels, L, Ponsioen, C, Wallace, I, Wyeth, J, Florholmen, J, Jahnsen, J, Lygren, I, Röseth, A, Ciecko Michalska, I, Gonciarz, M, Huk, J, Jamrozik Kruk, Z, Kondusz Szklarz, M, Paradowski, L, Wiechowska Kozlowska, A, Han, Ds, Hong, Sp, Kim, Js, Kim, Ko, Kim, Yh, Yang, Sk, Alexeeva, O, Bunkova, E, Burnevich, E, Dolgikh, O, Kasherininova, I, Khovaeva, Y, Lakhin, A, Ling, Kl, Bester, F, Coetzer, T, Grundling Hde, K, Jackson, Ld, Spies, P, Wright, Jp, Ziady, C, Garcia Planella, E, Perez Gisbert, J, Rogler, G, Seibold, F, Kao, Aw, Wu, Dc, Atug, O, Kurdas, Oo, Hawthorne, Ab, Lindsay, J, Abreu, M, Aggarwal, A, Bala, N, Becker, S, Behm, B, Braun, R, Cohn, W, Cross, R, Dar, S, Dassopoulos, T, De Villiers, W, Desta, T, Dryden, G, Duvall, A, Farraye, F, Fein, S, Liu, Bf, Gatof, D, Geenen, D, Ginsburg, P, Glover, S, Gopal, V, Hanson, J, Hardi, R, Isaacs, K, Jain, R, Karyotakis, N, Korzenik, J, Koshy, G, Koval, G, Lawitz, E, Lee, S, Loftus, E, Luther, R, Mahadevan, U, Mannon, P, Matsuyama, R, Mcintosh, A, Melmed, G, Mirkin, K, Nichols, M, Oubre, B, Pandak, W, Quadri, A, Quallich, L, Randall, C, Rausher, D, Regueiro, M, Safdi, A, Sands, B, Scherl, E, Schneier, J, Schwartz, D, Sedghi, S, Shafran, I, Siegel, C, Stein, L, Tatum, H, Weinberg, D, Winston, B, Wolf, D, Younes, Z, Jewell, D, Mahon, J, Rothstein, R, Snydman, D, Massaro, J, Clifford, D, Berger, J, Major, E, Provenzale, J, Abstract, Lev M.

Publikováno v: Feagan, B G, Rutgeerts, P, Sands, B E, Hanauer, S, Colombel, J-F, Sandborn, W J, Van Assche, G, Axler, J, Kim, H-J, Danese, S, Fox, I, Milch, C, Sankoh, S, Wyant, T, Xu, J, Parikh, A, GEMINI 1 Study Group & Andersen, V 2013, ' Vedolizumab as induction and maintenance therapy for ulcerative colitis ', The New England Journal of Medicine, vol. 369, no. 8, pp. 699-710 . https://doi.org/10.1056/NEJMoa1215734

Gut-selective blockade of lymphocyte trafficking by vedolizumab may constitute effective treatment for ulcerative colitis.We conducted two integrated randomized, double-blind, placebo-controlled trials of vedolizumab in patients with active disease.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f535f6a4645de35bab1c956ec0c8158
https://pubmed.ncbi.nlm.nih.gov/23964940

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