Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Tatsuya Yoshihara"'
Autor:
Masanari Shiramoto, Tatsuya Yoshihara, Wolfgang Schmider, Hiroki Takagi, Irene Nowotny, Miyuki Kajiwara, Hideya Muto
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract This study compared the pharmacokinetic and glucodynamic profiles of biosimilar SAR341402 insulin aspart to Japan-approved insulin aspart (NovoRapid) in healthy Japanese males. In this single-center, randomized, double-blind, single-dose, tw
Externí odkaz:
https://doaj.org/article/91ffc0df4bcd43f98107227aa96b64ad
Autor:
Tatsuya Yoshihara, Masayoshi Zaitsu, Fumie Shiraishi, Hisatomi Arima, Fumi Takahashi-Yanaga, Masaki Arioka, Shunichi Kajioka, Toshiyuki Sasaguri
Publikováno v:
Journal of Pharmacological Sciences, Vol 139, Iss 3, Pp 209-214 (2019)
The aim of this study was to investigate the contribution of gene polymorphisms, in combination with habitual caffeine consumption, to the effect of caffeine intake on hemodynamic and psychoactive parameters. A double-blind, prospective study was con
Externí odkaz:
https://doaj.org/article/1e787059475c4db09f821287885301d4
Autor:
Ai Fujita, Kengo Hayamizu, Tatsuya Yoshihara, Masayoshi Zaitsu, Fumie Shiraishi, Hisatomi Arima, Kazumasa Matsuo, Kanako Shiokawa, Hidekazu Setoguchi, Toshiyuki Sasaguri
Publikováno v:
JA Clinical Reports, Vol 4, Iss 1, Pp 1-8 (2018)
Abstract Introduction To examine whether sex and polymorphisms of cytochrome P450 (CYP) 2B6 and UDP-glucuronosyltransferase (UGT) 1A9 affect the difference between predicted and measured plasma propofol concentration during continuous infusion by tar
Externí odkaz:
https://doaj.org/article/d32fe09cfcd04061bc5ae461c678b876
Autor:
Naoya Kubokura, Fumi Takahashi-Yanaga, Masaki Arioka, Tatsuya Yoshihara, Kazunobu Igawa, Katsuhiko Tomooka, Sachio Morimoto, Yoshimichi Nakatsu, Teruhisa Tsuzuki, Yusaku Nakabeppu, Takayuki Matsumoto, Takanari Kitazono, Toshiyuki Sasaguri
Publikováno v:
Journal of Pharmacological Sciences, Vol 127, Iss 4, Pp 446-455 (2015)
Differentiation-inducing factor-1 (DIF-1) produced by Dictyostelium discoideum strongly inhibits the proliferation of various types of cancer cells by suppression of the Wnt/β-catenin signal transduction pathway. In the present study, we examined th
Externí odkaz:
https://doaj.org/article/a01a3be87fcb40d49109f332c358a672
Autor:
Kentaro Jingushi, Toshihisa Nakamura, Fumi Takahashi-Yanaga, Etsuko Matsuzaki, Yutaka Watanabe, Tatsuya Yoshihara, Sachio Morimoto, Toshiyuki Sasaguri
Publikováno v:
Journal of Pharmacological Sciences, Vol 121, Iss 2, Pp 103-109 (2013)
Differentiation-inducing factor-1 (DIF-1), a morphogen for Dictyostelium discoideum, inhibits the proliferation of human cancer cell lines by suppressing the Wnt/β-catenin signaling pathway. In this study, we examined the effect of DIF-1 on c-Myc, a
Externí odkaz:
https://doaj.org/article/90601118b2654fb192711adffd7e4591
Autor:
Toshiyuki Sasaguri, Fumie Shiraishi, Tatsuya Yoshihara, Fumi Takahashi-Yanaga, Sachio Morimoto
Publikováno v:
Journal of Pharmacological Sciences, Vol 115, Iss 4, Pp 490-499 (2011)
Polymorphisms at codons 49 and 389 of the β1-adrenergic receptor gene have been shown to alter the receptor function in vitro, whereas it remains controversial whether they influence the response to β-blocker in vivo. In the present study, we inves
Externí odkaz:
https://doaj.org/article/38da2f49e41c494390ddc812f352ffa7
Autor:
Tomoko Matsuda, Fumi Takahashi-Yanaga, Tatsuya Yoshihara, Katsumi Maenaka, Yutaka Watanabe, Yoshikazu Miwa, Sachio Morimoto, Yuzuru Kubohara, Masato Hirata, Toshiyuki Sasaguri
Publikováno v:
Journal of Pharmacological Sciences, Vol 112, Iss 3, Pp 320-326 (2010)
We have reported that the differentiation-inducing factors (DIFs) DIF-1 and DIF-3, morphogens secreted from Dictyostelium discoideum, inhibit proliferation of several cancer cells via suppression of the Wnt/ β-catenin signaling pathway. However, the
Externí odkaz:
https://doaj.org/article/7c4ece585c3640dda2bce8f5704aa152
Publikováno v:
Reproduction in Domestic Animals. 57:149-156
Although it is well known that the ovulation occurs during a period of time after LH surge in dogs, there are few reports of observing the entire process of development, ovulation and luteinization of each follicle. This study aimed to detect the ovu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a20567676eb10f235ed874482d335f85
https://doi.org/10.1111/rda.14035
https://doi.org/10.1111/rda.14035
Autor:
Hiroki Takagi, Miyuki Kajiwara, Irene Nowotny, Masanari Shiramoto, Hideya Muto, Wolfgang Schmider, Tatsuya Yoshihara
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Scientific Reports
Scientific Reports
This study compared the pharmacokinetic and glucodynamic profiles of biosimilar SAR341402 insulin aspart to Japan-approved insulin aspart (NovoRapid) in healthy Japanese males. In this single-center, randomized, double-blind, single-dose, two-period,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b35348be8171f6c2a176b21c9b5311
https://doaj.org/article/91ffc0df4bcd43f98107227aa96b64ad
https://doaj.org/article/91ffc0df4bcd43f98107227aa96b64ad
Autor:
Masanari Shiramoto, Tatsuya Yoshihara, Wolfgang Schmider, Yoshinori Takahashi, Irene Nowotny, Miyuki Kajiwara, Hideya Muto
Publikováno v:
Clinical pharmacology in drug development. 11(6)
This phase 1 study compared the pharmacokinetic (PK) and glucose pharmacodynamic (PD) characteristics of biosimilar SAR342434 insulin lispro and Japan-reference Humalog insulin lispro. This was a randomized, double-blind, 2-period, crossover study. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f731ffa9be950864cb320cb56d1ebd
https://pubmed.ncbi.nlm.nih.gov/35166054
https://pubmed.ncbi.nlm.nih.gov/35166054