Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Tatsuya Ohhata"'
Autor:
Maya Suzuki, Satoshi Sakai, Kosuke Ota, Yuki Bando, Chiharu Uchida, Hiroyuki Niida, Masatoshi Kitagawa, Tatsuya Ohhata
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Pairs of sense and antisense transcriptions that are adjacent at their 5′ and 3′ regions are called divergent and convergent transcription, respectively. However, the structural properties of divergent/convergent transcription in differe
Externí odkaz:
https://doaj.org/article/83940cd66fbb418eae401c2f2358a754
Autor:
Tatsuya Ohhata, Maya Suzuki, Satoshi Sakai, Kosuke Ota, Hazuki Yokota, Chiharu Uchida, Hiroyuki Niida, Masatoshi Kitagawa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Cis-natural antisense transcripts (cis-NATs) are transcribed from the same genomic locus as their partner gene but from the opposite DNA strand and overlap with the partner gene transcript. Here, we developed a simple and convenient program
Externí odkaz:
https://doaj.org/article/be2471143ee647f58a9585074de508c9
Autor:
Takahito Suzuki, Satoshi Sakai, Kosuke Ota, Mika Yoshida, Chiharu Uchida, Hiroyuki Niida, Takafumi Suda, Masatoshi Kitagawa, Tatsuya Ohhata
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 17011 (2023)
Long non-coding RNAs (lncRNAs) play a critical role in a variety of human diseases such as cancer. Here, to elucidate a novel function of a lncRNA called LINC00173, we investigated its binding partner, target gene, and its regulatory mechanism in lun
Externí odkaz:
https://doaj.org/article/9e856b4e1c8b4746baf0b9230e8093b2
Autor:
Tatsuya Ohhata, Kazuki Yamazawa, Asuka Miura-Kamio, Saori Takahashi, Satoshi Sakai, Yuka Tamura, Chiharu Uchida, Kyoko Kitagawa, Hiroyuki Niida, Ichiro Hiratani, Hisato Kobayashi, Hiroshi Kimura, Anton Wutz, Masatoshi Kitagawa
Publikováno v:
Cell Reports, Vol 34, Iss 13, Pp 108912- (2021)
Summary: The fine-scale dynamics from euchromatin (EC) to facultative heterochromatin (fHC) has remained largely unclear. Here, we focus on Xist and its silencing initiator Tsix as a paradigm of transcription-mediated conversion from EC to fHC. In mo
Externí odkaz:
https://doaj.org/article/4b9d9f2858de47159760643071866902
Autor:
Hiroyuki Niida, Ryoichi Matsunuma, Ryo Horiguchi, Chiharu Uchida, Yuka Nakazawa, Akira Motegi, Koji Nishimoto, Satoshi Sakai, Tatsuya Ohhata, Kyoko Kitagawa, Shinichi Moriwaki, Hideo Nishitani, Ayako Ui, Tomoo Ogi, Masatoshi Kitagawa
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Repair of cyclobutane pyrimidine dimers requires access to DNA by the nucleotide excision repair machinery. Here the authors show that HBO1 facilitates accumulation of SNF2H and ACF1 to make chromatin more accessible after ultraviolet damage.
Externí odkaz:
https://doaj.org/article/7b24a512b5c14b5d8915f3a1439eca2b
Autor:
Hiroyuki Niida, Ryoichi Matsunuma, Ryo Horiguchi, Chiharu Uchida, Yuka Nakazawa, Akira Motegi, Koji Nishimoto, Satoshi Sakai, Tatsuya Ohhata, Kyoko Kitagawa, Shinichi Moriwaki, Hideo Nishitani, Ayako Ui, Tomoo Ogi, Masatoshi Kitagawa
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-3 (2018)
Nature Communications 8: Article number: 16102 (2017); Published online 18 July 2017; Updated 20 April 2018 The original version of this Article contained an error in Fig. 1b, in which the cells were incorrectly labelled as ‘HeLa’, rather than th
Externí odkaz:
https://doaj.org/article/b76aa05dd11344338f7436e36f9c1b98
Autor:
Masashi Mikamo, Kyoko Kitagawa, Satoshi Sakai, Chiharu Uchida, Tatsuya Ohhata, Koji Nishimoto, Hiroyuki Niida, Sayuri Suzuki, Keiichi I. Nakayama, Naoki Inui, Takafumi Suda, Masatoshi Kitagawa
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 2, p 474 (2018)
Idiopathic pulmonary fibrosis (IPF) is a progressive disease with poor prognosis and no curative therapies. SCF-Skp2 E3 ligase is a target for cancer therapy, but there have been no reports about Skp2 as a target for IPF. Here we demonstrate that Skp
Externí odkaz:
https://doaj.org/article/58e6dd9106764011b4617ddf7f333755
Autor:
Masatoshi Kitagawa, Takafumi Suda, Akira Motegi, Kyoko Kitagawa, Tatsuya Ohhata, Chiharu Uchida, Hiroyuki Niida, Koji Nishimoto
Supplementary Figure S1. Depletion of HDAC3 increases UV sensitivity and delays CPD removal. Supplementary Figure S2. HDAC3 does not interact with NER factors in the presence or absence UV irradiation. Supplementary Figure S3. HDAC3 facilitates XPC a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef00ff6612e6f2480f46705cbfcb2d01
https://doi.org/10.1158/1541-7786.22527261.v1
https://doi.org/10.1158/1541-7786.22527261.v1
Autor:
Masatoshi Kitagawa, Takafumi Suda, Haruhiko Sugimura, Yojiro Kotake, Hiroyuki Niida, Chiharu Uchida, Koji Nishimoto, Masashi Mikamo, Kyoko Kitagawa, Tatsuya Ohhata, Satoshi Sakai, Masanori Harada
Table S1: Sequences of oligonucleotides, Table S2: Patient characteristics, Table S3: Univariate and Multivariate analysis of SCC; Supplementary Table S4. Correlation of NKX2-1 and YB-1 expression in NSCLCs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631978cf784c8e4f13d473c3755d7523
https://doi.org/10.1158/1541-7786.22512163
https://doi.org/10.1158/1541-7786.22512163
Autor:
Masatoshi Kitagawa, Takafumi Suda, Akira Motegi, Kyoko Kitagawa, Tatsuya Ohhata, Chiharu Uchida, Hiroyuki Niida, Koji Nishimoto
Recent studies have demonstrated that lysine acetylation of histones is crucial for nucleotide excision repair (NER) by relaxing the chromatin structure, which facilitates the recruitment of repair factors. However, few studies have focused on the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40789c2e85d2884bcd7ce78864fc5b6e
https://doi.org/10.1158/1541-7786.c.6545373.v1
https://doi.org/10.1158/1541-7786.c.6545373.v1