Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Tatsuya Kusudo"'
Autor:
Takako Mukai, Tatsuya Kusudo
Publikováno v:
PeerJ, Vol 11, p e14785 (2023)
Background Brown adipose tissue (BAT) dissipates caloric energy as heat and plays a role in glucose and lipid metabolism. Therefore, augmentation and activation of BAT are the focus of new treatment strategies against obesity, a primary risk factor o
Externí odkaz:
https://doaj.org/article/ec83db51c6ea4422b7cb267b4bd795d4
Publikováno v:
FEBS Open Bio, Vol 7, Iss 7, Pp 1009-1016 (2017)
Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence worldwide and has been identified as a risk factor for cirrhosis and hepatocellular carcinoma. However, there is no effective pharmacologic treatment for NAFLD. FABP1 is a liver‐s
Externí odkaz:
https://doaj.org/article/fb22317f70ef4eb0a974f4ed3b7eb923
Autor:
Hitoshi Yamashita, Tatsuya Kusudo, Tamaki Takeuchi, Shanlou Qiao, Kaname Tsutsumiuchi, Ting Wang, Youxue Wang
Publikováno v:
Journal of Functional Foods, Vol 19, Iss , Pp 320-329 (2015)
Evodiamine is a major alkaloid extracted from the fruit of Evodia fructus, which reduces diet-induced obesity in young animals. We investigated the effects of long-term dietary supplementation with evodiamine on obesity, insulin resistance and longev
Externí odkaz:
https://doaj.org/article/1916dc303b534e488a78aece64cd358b
Autor:
Ting Wang, Tatsuya Kusudo, Tamaki Takeuchi, Yukari Yamashita, Yasuhide Kontani, Yuko Okamatsu, Masayuki Saito, Nozomu Mori, Hitoshi Yamashita
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83264 (2013)
Evodiamine, an alkaloid extracted from the dried unripe fruit of the tree Evodia rutaecarpa Bentham (Rutaceae), reduces obesity and insulin resistance in obese/diabetic mice; however, the mechanism underlying the effect of evodiamine on insulin resis
Externí odkaz:
https://doaj.org/article/b7325fd956934d2ea75e3078ffd6b170
Autor:
Yuki Endo, Michihiro Hashimoto, Tatsuya Kusudo, Tadashi Okada, Tamaki Takeuchi, Ayumi Goto, Hitoshi Yamashita
Publikováno v:
Genes to cells : devoted to molecularcellular mechanismsREFERENCES. 27(3)
Thermogenic brown and beige adipocytes express uncoupling protein 1 (UCP1) and stimulate energy metabolism, protecting against obesity and metabolic diseases such as type 2 diabetes and hyperlipidemia. Cellular repressor of E1A-stimulated genes 1 (CR
Autor:
Naoya Kataoka, Yongxue Li, Aya Nozaki, Hitoshi Yamashita, Tatsuya Kusudo, Michihiro Hashimoto
Publikováno v:
The Journal of Biochemistry. 165:47-55
Brown adipocytes play a critical role for adaptive thermogenesis to regulate body temperature in cold or to circumvent diet-induced obesity. In this study, we investigated the role of cellular repressor of E1A-stimulated genes 1 (CREG1) on brown adip
Publikováno v:
FEBS Open Bio
Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence worldwide and has been identified as a risk factor for cirrhosis and hepatocellular carcinoma. However, there is no effective pharmacologic treatment for NAFLD. FABP1 is a liver‐s
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1866(7)
Brown adipose tissue (BAT) plays a critical role in lipid metabolism and may protect from hyperlipidemia; however, its beneficial effect appears to depend on the ambient temperature of the environment. In this study, we investigated the effects of un
Autor:
Naoki Osato, Wataru Nomura, Takako Mukai, Haruya Takahashi, Huei-Fen Jheng, Shigeto Seno, Kazuo Inoue, Yu Sheng Yeh, Hideo Matsuda, Tatsuya Kusudo, Mari Iwase, Sigenobu Matsumura, Tsuyoshi Goto, Teruo Kawada, Soshi Tokiwa
Publikováno v:
J Biol Chem
Browning of adipose tissue is induced by specific stimuli such as cold exposure and consists of up-regulation of thermogenesis in white adipose tissue. Recently, it has emerged as an attractive target for managing obesity in humans. Here, we performe
Autor:
Tatsuya Kusudo, Kaname Tsutsumiuchi, Hitoshi Yamashita, Tamaki Takeuchi, Ting Wang, Shanlou Qiao, Youxue Wang
Publikováno v:
Journal of Functional Foods, Vol 19, Iss, Pp 320-329 (2015)
Evodiamine is a major alkaloid extracted from the fruit of Evodia fructus, which reduces diet-induced obesity in young animals. We investigated the effects of long-term dietary supplementation with evodiamine on obesity, insulin resistance and longev