Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Tatsuya IWANAGA"'
Autor:
Hitomi Kurokawa, Kentaro Kato, Tatsuya Iwanaga, Tatsuki Sugi, Atsushi Sudo, Kyousuke Kobayashi, Haiyan Gong, Hitoshi Takemae, Frances C Recuenco, Taisuke Horimoto, Hiroomi Akashi
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22492 (2011)
cAMP-dependent protein kinase (PKA) has been implicated in the asexual stage of the Toxoplasma gondii life cycle through assaying the effect of a PKA-specific inhibitor on its growth rate. Since inhibition of the host cell PKA cannot be ruled out, a
Externí odkaz:
https://doaj.org/article/c3963847f8c8482a85c39c030262e1a9
Publikováno v:
IEEJ Transactions on Industry Applications. 141:138-146
Autor:
Taisuke Horimoto, Norasuthi Bangphoomi, Chieko Shioda, Kazuyuki Uchida, Yukari Ishihara, Shumpei Tsuda, Tatsuya Iwanaga, Akiko Takenaka-Uema, Kentaro Kato, Keita Sugiura, Shin Murakami, Kohei Saeki, Hiroomi Akashi
Publikováno v:
The Journal of Veterinary Medical Science
The biological function of a nonstructural protein, NSm, of Akabane virus (AKAV) is unknown. In this study, we generated a series of NSm deletion mutant viruses by reverse genetics and compared their phenotypes. The mutant in which the NSm coding reg
Publikováno v:
Parasitology International. 61:224-234
Inhibitors of cellular protein kinases have been reported to inhibit the development of Apicomplexan parasites, suggesting that the functions of protozoan protein kinases are critical for their life cycle. However, the specific roles of these protein
Autor:
Keizo Sato, Kazumi Sasamoto, Yoshihiro Mitani, Tatsuya Iwanaga, Yosuke Muramoto, Tomohiro Karakawa, Tetsuji Nabeshima, Kazuhiko Ishida, Kazuko Nakagawa, Masataka Kitamado, Kumiko Maruyama
Publikováno v:
Biochemical and Biophysical Research Communications. 370:93-97
Electron spin resonance using spin-trapping is a useful technique for detecting direct reactive oxygen species, such as superoxide ( O 2 · - ). However, the widely used spin trap 2,2-dimethyl-3,4-dihydro-2H-pyrrole N-oxide (DMPO) has several fundame
Autor:
Taisuke Horimoto, Hitoshi Takemae, Kyousuke Kobayashi, Kentaro Kato, Hiroomi Akashi, Tatsuki Sugi, Tatsuya Iwanaga, Haiyan Gong, Frances C. Recuenco, Hitomi Kurokawa
Publikováno v:
Journal of Veterinary Medical Science. 73:1377-1379
Bumped kinase inhibitors (BKIs) target analog-sensitive kinases, which the genomes of mammals rarely encode. Previously, we demonstrated that a BKI effectively suppressed the in vitro replication of Toxoplasma gondii, the causative pathogen of toxopl
Autor:
Hitoshi Takemae, Taisuke Horimoto, Noreen Grace V. Fundador, Fumi Murakoshi, Yukiko Enomoto-Rogers, Frances C. Recuenco, Tatsuki Sugi, Haiyan Gong, Atsuko Inomata, Akiko Ishiwa, Tadahisa Iwata, Kyousuke Kobayashi, Kentaro Kato, Tatsuya Iwanaga
Publikováno v:
Scientific Reports
Here, we assessed the sulfated derivative of the microbial polysaccharide gellan gum and derivatives of λ and κ-carrageenans for their ability to inhibit Plasmodium falciparum 3D7 and Dd2 growth and invasion of red blood cells in vitro. Growth inhi
Autor:
Hitoshi Takemae, Frances C. Recuenco, Ryo Takano, Haiyan Gong, Akiko Ishiwa, Hiroomi Akashi, Tatsuya Iwanaga, Kyousuke Kobayashi, Kentaro Kato, Taisuke Horimoto, Tatsuki Sugi
Publikováno v:
Scientific Reports
CORRIGENDUM: Analyses of Interactions Between Heparin and the Apical Surface Proteins of Plasmodium falciparum
Autor:
Hitoshi Takemae, Hiroomi Akashi, Kyousuke Kobayashi, Akiko Ishiwa, Taisuke Horimoto, Haiyan Gong, Tatsuki Sugi, Frances C. Recuenco, Kentaro Kato, Tatsuya Iwanaga, Ryo Takano
Publikováno v:
Scientific Reports
Heparin, a sulfated glycoconjugate, reportedly inhibits the blood-stage growth of the malaria parasite Plasmodium falciparum. Elucidation of the inhibitory mechanism is valuable for developing novel invasion-blocking treatments based on heparin. Mero
Autor:
Atsuko Inomata, Akiko Ishiwa, Fumi Murakoshi, Taisuke Horimoto, Frances C. Recuenco, Hitoshi Takemae, Hiroomi Akashi, Haiyan Gong, Tatsuki Sugi, Kyousuke Kobayashi, Tatsuya Iwanaga, Kentaro Kato
Publikováno v:
Scientific Reports
Toxoplasma rhoptry neck protein 4 (TgRON4) is a component of the moving junction macromolecular complex that plays a central role during invasion. TgRON4 is exposed on the cytosolic side of the host cell during invasion, but its molecular interaction