Zobrazeno 1 - 10
of 250
pro vyhledávání: '"Tatsuya IOKA"'
Autor:
Kei Furuya, Masao Nakajima, Ryouichi Tsunedomi, Yuki Nakagami, Ming Xu, Hiroto Matsui, Yukio Tokumitsu, Yoshitaro Shindo, Yusaku Watanabe, Shinobu Tomochika, Noriko Maeda, Michihisa Iida, Nobuaki Suzuki, Shigeru Takeda, Shoichi Hazama, Tatsuya Ioka, Yoshinobu Hoshii, Tomio Ueno, Hiroaki Nagano
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background To improve the prognosis of patients with metastatic colorectal cancer (mCRC), investigating predictive biomarkers of their prognosis and chemotherapeutic responsiveness is necessary. This study aimed to analyze the clinical signi
Externí odkaz:
https://doaj.org/article/6147b1272ad342a6a9b324c9d9762daa
Autor:
Ikuo Nakamura, Etsuro Hatano, Hideo Baba, Keiko Kamei, Hiroshi Wada, Junzo Shimizu, Masashi Kanai, Kenichi Yoshimura, Hiroaki Nagano, Tatsuya Ioka
Publikováno v:
Annals of Gastroenterological Surgery, Vol 7, Iss 6, Pp 1009-1020 (2023)
Abstract Purpose Gemcitabine, cisplatin, and S‐1 chemotherapy was superior to gemcitabine and cisplatin chemotherapy for progression‐free survival and overall survival for unresectable and recurrent biliary tract cancer in a randomized phase III
Externí odkaz:
https://doaj.org/article/a82617ae42c94aab918ef237a4d2e2aa
Autor:
Hiroto Matsui, Yoshitaro Shindo, Daisaku Yamada, Hiroyuki Ogihara, Yukio Tokumitsu, Masao Nakajima, Michihisa Iida, Nobuaki Suzuki, Shigeru Takeda, Yuki Nakagami, Shogo Kobayashi, Hidetoshi Eguchi, Tatsuya Ioka, Yoshihiko Hamamoto, Hiroaki Nagano
Publikováno v:
BMC Surgery, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Since clinically relevant postoperative pancreatic fistula (CR-POPF) can cause intra-abdominal hemorrhage and abscesses, leading to surgery-related deaths after pancreaticoduodenectomy (PD), its preoperative prediction is importan
Externí odkaz:
https://doaj.org/article/89624868656446229dbc2fb4defa9a8c
Publikováno v:
Annals of Gastroenterological Surgery, Vol 7, Iss 4, Pp 565-571 (2023)
Abstract Biliary tract cancer (BTCs) is a heterogeneous malignancy divided into cholangiocarcinoma, gallbladder cancer, and ampullary cancer. Due to little or no symptoms, most patients with BTCs are diagnosed with unresectable or metastatic disease.
Externí odkaz:
https://doaj.org/article/cb39ddc8a93542da9268d6b4afe3ba10
Autor:
Yutaka Fujiwara, Yasutoshi Kuboki, Masayuki Furukawa, Nobumasa Mizuno, Hiroki Hara, Tatsuya Ioka, Makoto Ueno, Yasuo Takahashi, Shunji Takahashi, Shinji Takeuchi, Christine Lihou, Tao Ji, Chenwei Tian, Toshio Shimizu
Publikováno v:
Cancer Medicine, Vol 12, Iss 9, Pp 10597-10611 (2023)
Abstract Background FIGHT‐102 was a phase 1, dose‐escalation, dose‐expansion study of pemigatinib in Japanese patients with advanced solid tumors. Here, we report safety, tolerability, and preliminary efficacy of pemigatinib from FIGHT‐102. M
Externí odkaz:
https://doaj.org/article/9baedb4c4d12487081450e5da764609a
Autor:
Kou Kanesada, Ryouichi Tsunedomi, Shoichi Hazama, Hiroyuki Ogihara, Yoshihiko Hamamoto, Yoshitaro Shindo, Hiroto Matsui, Yukio Tokumitsu, Shin Yoshida, Michihisa Iida, Nobuaki Suzuki, Shigeru Takeda, Tatsuya Ioka, Hiroaki Nagano
Publikováno v:
Cancer Medicine, Vol 12, Iss 4, Pp 4294-4305 (2023)
Abstract Objective Irinotecan is a useful anticancer drug for colorectal cancer treatment. UGT1A1*28 and *6 gene polymorphisms are known risk factors for irinotecan‐associated toxicity. However, severe adverse effects due to irinotecan have been ob
Externí odkaz:
https://doaj.org/article/d2d4ebd49a3344b5a97523696e1028b6
Autor:
Yuki Nakagami, Shoichi Hazama, Nobuaki Suzuki, Shin Yoshida, Shinobu Tomochika, Hiroto Matsui, Yoshitaro Shindo, Yukio Tokumitsu, Satoshi Matsukuma, Yusaku Watanabe, Michihisa Iida, Ryouichi Tsunedomi, Shigeru Takeda, Tomonobu Fujita, Yutaka Kawakami, Hiroyuki Ogihara, Yoshihiko Hamamoto, Tatsuya Ioka, Tsuyoshi Tanabe, Tomio Ueno, Hiroaki Nagano
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background We recently reported the relapse-free survival (RFS) significance of the combination of CD4+ and forkhead box P3+ (FOXP3) T-cell densities identified by immunohistochemistry in patients with stage I, II, and III colorectal cancer
Externí odkaz:
https://doaj.org/article/a65fed79f92a4ae7a05efc75f2782f64
Autor:
Yuichiro Doki, Makoto Ueno, Chih‐Hung Hsu, Do‐Youn Oh, Keunchil Park, Noboru Yamamoto, Tatsuya Ioka, Hiroki Hara, Manabu Hayama, Masahiro Nii, Keiko Komuro, Mariko Sugimoto, Makoto Tahara
Publikováno v:
Cancer Medicine, Vol 11, Iss 13, Pp 2550-2560 (2022)
Abstract Background Agents targeting the programmed cell death‐1 pathway have demonstrated encouraging activity across multiple solid tumor types. The dose expansion phase of this phase I study evaluated the safety, tolerability, and antitumor acti
Externí odkaz:
https://doaj.org/article/72cee212174440e8a67e123a8cdd7829
Autor:
Tanios Bekaii-Saab, Takuji Okusaka, David Goldstein, Do-Youn Oh, Makoto Ueno, Tatsuya Ioka, Weijia Fang, Eric C. Anderson, Marcus S. Noel, Michele Reni, Hye Jin Choi, Jonathan S. Goldberg, Sang Cheul Oh, Chung-Pin Li, Josep Tabernero, Jian Li, Emma Foos, Cindy Oh, Eric Van Cutsem
Publikováno v:
EClinicalMedicine, Vol 58, Iss , Pp 101897- (2023)
Summary: Background: Compared with normal cells, tumour cells contain elevated levels of reactive oxygen species (ROS). Increased levels of the antioxidant protein NAD(P)H:quinone oxidoreductase 1 (NQO1) and phosphorylated signal transducer and activ
Externí odkaz:
https://doaj.org/article/5dbeea00320a4570827b5add5de5eb9c
Autor:
Ryouichi Tsunedomi, Kiyoshi Yoshimura, Yuta Kimura, Mitsuo Nishiyama, Nobuyuki Fujiwara, Satoshi Matsukuma, Shinsuke Kanekiyo, Hiroto Matsui, Yoshitaro Shindo, Yusaku Watanabe, Yukio Tokumitsu, Shin Yoshida, Michihisa Iida, Nobuaki Suzuki, Shigeru Takeda, Tatsuya Ioka, Shoichi Hazama, Hiroaki Nagano
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Cancer stem cells (CSCs) are thought to play important roles in carcinogenesis, recurrence, metastasis, and therapy-resistance. We have successfully induced cancer stem-like sphere cells (CSLCs) which possess enhanced chemoresista
Externí odkaz:
https://doaj.org/article/4ba9390be14d4630a56ccd087fcb0797