Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Tatsuya, Mitsumoto"'
Autor:
Kensuke Satomoto, Isamu Suzuki, Koji Mita, Atsushi Wakita, Hiroshi Yamagata, Tatsuya Mitsumoto, Shuichi Hamada
Publikováno v:
Genes and Environment, Vol 44, Iss 1, Pp 1-7 (2022)
Abstract Background The repeated-dose liver micronucleus (RDLMN) assay has been well-developed and applied because of its simplicity and the ease of integration into general toxicity studies which is the preferred method from the 3R’s point of view
Externí odkaz:
https://doaj.org/article/e6673651f7634250afa629763e88b950
Autor:
Shuichi Hamada, Miyuki Shigano, Yumi Wako, Kazufumi Kawasako, Kensuke Satomoto, Tatsuya Mitsumoto, Takayuki Fukuda, Wakako Ohyama, Takeshi Morita, Makoto Hayashi
Publikováno v:
Genes and Environment, Vol 44, Iss 1, Pp 1-9 (2022)
Abstract Background Currently, revisions to the ICH S1 guidance on rodent carcinogenicity testing are being proposed. Application of this approach would reduce the use of animals in accordance with the 3Rs principles (reduce/refine/replace). The meth
Externí odkaz:
https://doaj.org/article/dcffae53b6f441a4900b515615998fe7
Autor:
Shinji Takasu, Yuji Ishii, Moeka Namiki, Kenji Nakamura, Tatsuya Mitsumoto, Norifumi Takimoto, Takehiko Nohmi, Kumiko Ogawa
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
The safety of flavoring agents has been evaluated according to classification by chemical structure and using a decision tree approach. The genotoxic potential found in some flavoring agents has highlighted the importance of efficient toxicity studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6089f633596b5db0b4cf32464cafe3b
https://pubmed.ncbi.nlm.nih.gov/36464108
https://pubmed.ncbi.nlm.nih.gov/36464108
Autor:
Hiroshi Yamagata, Tsubasa Saito, Takezo Okamoto, Kensuke Satomoto, Tatsuya Mitsumoto, Atsushi Wakita, Maki Nakamura, Takahiro Hayashi, Yuichi Kuroiwa
Publikováno v:
Journal of toxicologic pathology. 35(4)
The carcinogenicity of 2,2'-[1,2-ethanediylbis(oxymethylene)]bis-oxirane (ethylene glycol diglycidyl ether; EGDE), 3-hydroxy-2-naphthoic acid (HNA), and acetoacetanilide (AAA) was investigated using a medium-term rat liver bioassay for an occupationa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af086c1ef8e844a45f12bf9dac270da3
https://pubmed.ncbi.nlm.nih.gov/36406173
https://pubmed.ncbi.nlm.nih.gov/36406173
Autor:
Yuji Ishii, Kenji Nakamura, Tatsuya Mitsumoto, Norifumi Takimoto, Moeka Namiki, Shinji Takasu, Kumiko Ogawa
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 161
Madder color (MC), a natural dye isolated from Rubia tinctorum, is a potent carcinogen that targets the outer stripe of outer medulla (OSOM) in the kidneys of rats. To clarify the role of MC components in renal carcinogenesis, we examined distributio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed6348a45b9de637a2077389215cfbb3
https://pubmed.ncbi.nlm.nih.gov/35139434
https://pubmed.ncbi.nlm.nih.gov/35139434
Lack of genotoxic mechanisms in isoeugenol-induced hepatocellular tumorigenesis in male B6C3F1 mice.
Autor:
Yuji Ishii, Moeka Namiki, Shinji Takasu, Kenji Nakamura, Norifumi Takimoto, Tatsuya Mitsumoto, Kumiko Ogawa
Publikováno v:
Japanese Journal of Food Chemistry & Safety; 2023, Vol. 30 Issue 1, p9-22, 14p
Publikováno v:
Regulatory Toxicology and Pharmacology. 127:105076
Myrrh is a flavoring agent and food additive. Here, we performed a subchronic toxicity study of Myrrh in male and female F344 rats by feeding at 5,000, 15,000 and 50,000 ppm for 90 days. No deaths or clinical signs were observed. Suppression of body
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab67e86a05e2527dd5561e0b69bcefe9
https://doi.org/10.1016/j.yrtph.2021.105076
https://doi.org/10.1016/j.yrtph.2021.105076
Autor:
Tiejiao, Zhang, Yosuke, Tachiya, Yuichi, Sakaguchi, Katsuhiko, Mitsumoto, Tatsuya, Mitsumoto, Nobuyoshi, Ohya, Masayuki, Sasaki
Publikováno v:
福岡醫學雜誌. 101(11):238-246
Objective : The aim of this study was to determine an appropriate threshold value for delineation of the target volume in PET/CT and to investigate whether we could delineate a target volume by phantom studies. Methods : A phantom consisted of six sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::66ed9955be3ecfc2b496aadc874164ca
http://hdl.handle.net/2324/18984
http://hdl.handle.net/2324/18984
Autor:
Yuichi Sakaguchi, Noriko Mizoguchi, Nobuyoshi Ohya, Yoshihiko Onizuka, Koichiro Abe, Tatsuya Mitsumoto, Koichiro Kaneko, Katsuhiko Mitsumoto, Kazuhiko Himuro, Shingo Baba, Masayuki Sasaki
Publikováno v:
Annals of Nuclear Medicine. 24(8):585-591
We evaluated the partial volume effect in PET/CT images and developed a simple correction method to address this problem. Six spheres and the background in the phantom were filled with F-18 and we thus obtained 4 different sphere-to-background (SB) r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a86973d7d52d1dc45eccb7d0b86908
http://hdl.handle.net/2324/26103
http://hdl.handle.net/2324/26103
Autor:
Nobuyoshi Ohya, Yosuke Tachiya, Masayuki Sasaki, Yuichi Sakaguchi, Tiejiao Zhang, Katsuhiko Mitsumoto, Tatsuya Mitsumoto
Publikováno v:
Annals of Nuclear Medicine. 24(7):507-514
The aim of this study was to investigate the utility of gated PET/CT and CT attenuation correction (AC) for the quantitation of radioactivity. An ellipse phantom containing six spheres, ranging from 10 to 37 mm in diameter, was filled with 36.7 kBq/m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8683ca90facfc3a13d5a20f6b28d618c
http://hdl.handle.net/2324/26102
http://hdl.handle.net/2324/26102