Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Tatsuya, Arai"'
Autor:
Daisuke Sasaki, Tatsuya Arai, Yue Yang, Masahiro Kuramochi, Wakako Furuyama, Asuka Nanbo, Hiroshi Sekiguchi, Nobuhiro Morone, Kazuhiro Mio, Yuji C. Sasaki
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101712- (2024)
Single-molecule intramolecular dynamics were successfully measured for three variants of SARS-CoV-2 spike protein, alpha: B.1.1.7, delta: B.1.617, and omicron: B.1.1.529, with a time resolution of 100 μs using X-rays. The results were then compared
Externí odkaz:
https://doaj.org/article/e11640f8ec6b41749adcc6e2be830094
Autor:
Kazuhiro Mio, Tatsunari Ohkubo, Daisuke Sasaki, Mayui Sugiura, Kayoko Kawaguchi, Kazutaka Araki, Keizaburo Taninaka, Masaki Sakaguchi, Shunsuke Nozawa, Tatsuya Arai, Yuji C. Sasaki
Publikováno v:
Membranes, Vol 14, Iss 4, p 75 (2024)
Protein dynamics play important roles in biological functions, which accompany allosteric structure changes. Diffracted X-ray blinking (DXB) uses monochromatic X-rays and nanocrystal probes. The intramolecular motion of target proteins is analyzed fr
Externí odkaz:
https://doaj.org/article/4338b407ac3f4b2b83dc2cf75de5ef2a
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Many psychrophilic microorganisms synthesize ice-binding proteins (IBPs) to survive the cold. The functions of IBPs are evaluated by the effect of the proteins on the nonequilibrium water freezing-point depression, which is called “thermal
Externí odkaz:
https://doaj.org/article/5552710c34c6481aad72fb0792671f7e
Autor:
Jaewon Chang, Tatsuya Arai, Masahiro Kuramochi, Rena Inamasu, Zhuoqi Lee, Tatsunari Ohkubo, Kazuhiro Mio, Yuji C. Sasaki
Publikováno v:
Biochemistry and Biophysics Reports, Vol 31, Iss , Pp 101298- (2022)
Acceleration of societal ageing has increased the global incidence of geriatric diseases such as Alzheimer's disease (AD), and the demands for proper diagnosis and monitoring of those diseases are also increasing daily. We utilized diffracted X-ray b
Externí odkaz:
https://doaj.org/article/8bb1c04dc7014d2598abd691f8461b48
Autor:
Kazuhiro Mio, Tatsunari Ohkubo, Daisuke Sasaki, Tatsuya Arai, Mayui Sugiura, Shoko Fujimura, Shunsuke Nozawa, Hiroshi Sekiguchi, Masahiro Kuramochi, Yuji C. Sasaki
Publikováno v:
Membranes, Vol 13, Iss 8, p 708 (2023)
The transient receptor potential vanilloid type 1 (TRPV1) is a multimodal receptor which responds to various stimuli, including capsaicin, protons, and heat. Recent advances in cryo-electron microscopy have revealed the structures of TRPV1. However,
Externí odkaz:
https://doaj.org/article/66186bc20f344ab89a24b7591ee82655
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Antifreeze proteins (AFPs) inhibit ice growth by adsorbing onto specific ice planes. Microbial AFPs show diverse antifreeze activity and ice plane specificity, while sharing a common molecular scaffold. To probe the molecular mechanisms resp
Externí odkaz:
https://doaj.org/article/42ba24df757847b982ec72a948e08652
Publikováno v:
Clinical Case Reports, Vol 8, Iss 12, Pp 2954-2960 (2020)
Abstract Mycoplasma pneumonia with mild CNS involvements should be considered of MERS, even in adult. From the case series, splenial single lesions by MRI and prodromal fever with varied neurological manifestations recovered completely by antibiotics
Externí odkaz:
https://doaj.org/article/19ed752b6a5e4050867d78c5582b720f
Autor:
Masahiro Kuramochi, Yige Dong, Yue Yang, Tatsuya Arai, Rio Okada, Yoichi Shinkai, Motomichi Doi, Kouki Aoyama, Hiroshi Sekiguchi, Kazuhiro Mio, Sakae Tsuda, Yuji C. Sasaki
Publikováno v:
Biochemistry and Biophysics Reports, Vol 29, Iss , Pp 101224- (2022)
The dynamic properties of protein molecules are involved in the relationship between their structure and function. Time-resolved X-ray observation enables capturing the structures of biomolecules with picometre-scale precision. However, this techniqu
Externí odkaz:
https://doaj.org/article/d51b7b0d33ea4dc7a01a263f0631b0b5
Autor:
Tatsuya Arai, Rena Inamasu, Hiroki Yamaguchi, Daisuke Sasaki, Ayana Sato-Tomita, Hiroshi Sekiguchi, Kazuhiro Mio, Sakae Tsuda, Masahiro Kuramochi, Yuji C. Sasaki
Publikováno v:
Structural Dynamics, Vol 8, Iss 4, Pp 044302-044302-10 (2021)
In recent years, real-time observations of molecules have been required to understand their behavior and function. To date, we have reported two different time-resolved observation methods: diffracted x-ray tracking and diffracted x-ray blinking (DXB
Externí odkaz:
https://doaj.org/article/ad9c3f53563d489c91231ad7292e49e4
Autor:
Rena Inamasu, Hiroki Yamaguchi, Tatsuya Arai, Jaewon Chang, Masahiro Kuramochi, Kazuhiro Mio, Yuji C. Sasaki
Publikováno v:
Polymer Journal.
Research on polymer surfaces has shown that the mobilities of polymer chains, which affect the aggregation state and thus the physical properties of the material, differ between the surface and bulk. However, the mobilities of the surface polymers ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc70991db2b65893da8dbc548a340f51
https://doi.org/10.1038/s41428-023-00762-z
https://doi.org/10.1038/s41428-023-00762-z