Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Tatsushi Yoshida"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Venetoclax has been approved recently for treatment of Acute myeloid leukemia (AML). Venetoclax is a BH3-mimetic and induces apoptosis via Bcl-2 inhibition. However, venetoclax’s effect is still restrictive and a novel strategy is needed.
Externí odkaz:
https://doaj.org/article/6c92633f6f8543138884a45123f04d5d
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract High transfection efficiency is the most important point for experiments of DNA and RNA introduction into cells. Decrease of cell viability during the transfection procedure is a crucial issue, resulting in transfection failure. However, the
Externí odkaz:
https://doaj.org/article/4a0c471400274bf5986b51642f0702ab
Autor:
Akifumi Matsumoto, Tatsushi Yoshida, Takahiro Shima, Kenta Yamasaki, Kenjiro Tadagaki, Noriko Kondo, Yasumichi Kuwahara, Dong-Er Zhang, Tsukasa Okuda
Publikováno v:
BBA Advances, Vol 2, Iss , Pp 100047- (2022)
The fusion protein RUNX1-ETO is an oncogenic transcription factor generated by t(8;21) chromosome translocation, which is found in FAB-M2-type acute myeloid leukemia (AML). RUNX1-ETO is known to dysregulate the normal RUNX1 transcriptional network, w
Externí odkaz:
https://doaj.org/article/4123691a17da41c0880e4d3e26cd54c0
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1202 (2020)
Parkinson’s disease (PD) is a common neurodegenerative disorder. Recent identification of genes linked to familial forms of PD has revealed that post-translational modifications, such as phosphorylation and ubiquitination of proteins, are key facto
Externí odkaz:
https://doaj.org/article/fead9747287549dbb851c97315549754
Autor:
Toshiyuki Sakai, Miki Wakada, Shusuke Yasuda, Ahmed E. Goda, Kimihiro Yano, Tatsushi Yoshida, Mano Horinaka, Hiroya Taniguchi
PDF file, 77K, ROS is not involved in the apoptosis induced by methylglyoxal with TRAIL.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351eb56df5c1453e8dd5298308967399
https://doi.org/10.1158/1535-7163.22498057.v1
https://doi.org/10.1158/1535-7163.22498057.v1
Autor:
Toshiyuki Sakai, Miki Wakada, Shusuke Yasuda, Ahmed E. Goda, Kimihiro Yano, Tatsushi Yoshida, Mano Horinaka, Hiroya Taniguchi
Methylglyoxal is an essential component in glycolysis and is known to be an inducer of apoptosis. Glyoxalase I (GLO1) metabolizes and inactivates methylglyoxal. GLO1 is known to be overexpressed in cancer cells and causes resistance to anticancer age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b07cabc7be41864f544c05dec1b0136
https://doi.org/10.1158/1535-7163.c.6535780.v1
https://doi.org/10.1158/1535-7163.c.6535780.v1
Autor:
Toshiyuki Sakai, Miki Wakada, Shusuke Yasuda, Ahmed E. Goda, Kimihiro Yano, Tatsushi Yoshida, Mano Horinaka, Hiroya Taniguchi
PDF file, 171K, Expression of TRAIL receptors when treated with methylglyoxal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0105f39aa949f35bbbd1119ed783ec75
https://doi.org/10.1158/1535-7163.22498060
https://doi.org/10.1158/1535-7163.22498060
Autor:
Baolin Zhang, Sun Young Moon, Tahira Khan, Junjie Chen, Leslie A. Rivera Rosado, Yaqin Zhang, Tatsushi Yoshida
Supplementary Data from Blockade of Rac1 Activity Induces G1 Cell Cycle Arrest or Apoptosis in Breast Cancer Cells through Downregulation of Cyclin D1, Survivin, and X-Linked Inhibitor of Apoptosis Protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f88374b1e2c0226344cf4f9bbcf85b
https://doi.org/10.1158/1535-7163.22484651
https://doi.org/10.1158/1535-7163.22484651
Autor:
Baolin Zhang, Sun Young Moon, Tahira Khan, Junjie Chen, Leslie A. Rivera Rosado, Yaqin Zhang, Tatsushi Yoshida
Rac1 GTPase regulates a variety of signaling pathways that are implicated in malignant phenotypes. Here, we show that selective inhibition of Rac1 activity by the pharmacologic inhibitor NSC23766 suppressed cell growth in a panel of human breast canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71af925b0c79af6029e276b8fc09e025
https://doi.org/10.1158/1535-7163.c.6531512
https://doi.org/10.1158/1535-7163.c.6531512
Autor:
Toshiyuki Sakai, Toshikazu Yoshikawa, Keisho Kataoka, Miki Wakada, Masako Konishi, Ahmed E. Goda, Takashi Yasuda, Mano Horinaka, Tatsushi Yoshida, Hiroya Taniguchi
Supplementary Figure 2 from Baicalein Overcomes Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Resistance via Two Different Cell-Specific Pathways in Cancer Cells but not in Normal Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af15439d207987c0e7a5a55a4bacac51
https://doi.org/10.1158/0008-5472.22375568
https://doi.org/10.1158/0008-5472.22375568