Zobrazeno 1 - 2
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pro vyhledávání: '"Tatsushi Samejima"'
Autor:
Masahiro Noji, Tatsushi Samejima, Keiichi Yamaguchi, Masatomo So, Keisuke Yuzu, Eri Chatani, Yoko Akazawa-Ogawa, Yoshihisa Hagihara, Yasushi Kawata, Kensuke Ikenaka, Hideki Mochizuki, József Kardos, Daniel E. Otzen, Vittorio Bellotti, Johannes Buchner, Yuji Goto
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Noji et al. test link between protein folding and misfolding upon heating and agitation. They show that folding and amyloid formation are separated by the supersaturation barrier of a protein, breakdown of which shifts the protein to the amyloid path
Externí odkaz:
https://doaj.org/article/ed4d8eeda119466189e820b1da445527
Autor:
Yuji Goto, Hideki Mochizuki, Yasushi Kawata, Tatsushi Samejima, Eri Chatani, Keisuke Yuzu, Masahiro Noji, Keiichi Yamaguchi, Vittorio Bellotti, Johannes Buchner, Masatomo So, Kensuke Ikenaka, Yoshihisa Hagihara, József Kardos, Yoko Akazawa-Ogawa, Daniel E. Otzen
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Noji, M, Samejima, T, Yamaguchi, K, So, M, Yuzu, K, Chatani, E, Akazawa-Ogawa, Y, Hagihara, Y, Kawata, Y, Ikenaka, K, Mochizuki, H, Kardos, J, Otzen, D E, Bellotti, V, Buchner, J & Goto, Y 2021, ' Breakdown of supersaturation barrier links protein folding to amyloid formation ', Communications Biology, vol. 4, no. 1, 120 . https://doi.org/10.1038/s42003-020-01641-6
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Noji, M, Samejima, T, Yamaguchi, K, So, M, Yuzu, K, Chatani, E, Akazawa-Ogawa, Y, Hagihara, Y, Kawata, Y, Ikenaka, K, Mochizuki, H, Kardos, J, Otzen, D E, Bellotti, V, Buchner, J & Goto, Y 2021, ' Breakdown of supersaturation barrier links protein folding to amyloid formation ', Communications Biology, vol. 4, no. 1, 120 . https://doi.org/10.1038/s42003-020-01641-6
The thermodynamic hypothesis of protein folding, known as the “Anfinsen’s dogma” states that the native structure of a protein represents a free energy minimum determined by the amino acid sequence. However, inconsistent with the Anfinsen’s d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4f8ce8e90e3abf591e1a429105ba35
https://hdl.handle.net/20.500.14094/90008224
https://hdl.handle.net/20.500.14094/90008224