Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tatsuro Teraoka"'
Autor:
Toshiya Inaba, Yoshio Hosoi, Yasushi Nagata, Kenji Kamiya, Mitsuru Nenoi, Atsushi Enomoto, Keiji Tanimoto, Chihiro Yanagawa, Yosuke Kawate, Shohei Ujita, Tatsuro Teraoka, Yurie Nishi, Akiko Sawa, Tetsuji Yamaguchi, Kaoru Tanaka, Shinya Ariyasu, Bing Wang, Shin Aoki, Megumi Sasatani, Ippei Takahashi, Akinori Morita
Figure S1. 5CHQ suppresses etoposide-induced apoptosis in wt-p53-expressing cells; Figure S2. Effect of 5CHQ on p53's DNA-binding to CDKN1A and BBC3 promoter oligonucleotides; Figure S3. 5CHQ by itself activates p53-mediated transcription; Figure S4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac26aee2d2df683bf490d032861b068
https://doi.org/10.1158/1535-7163.22504455
https://doi.org/10.1158/1535-7163.22504455
Autor:
Toshiya Inaba, Yoshio Hosoi, Yasushi Nagata, Kenji Kamiya, Mitsuru Nenoi, Atsushi Enomoto, Keiji Tanimoto, Chihiro Yanagawa, Yosuke Kawate, Shohei Ujita, Tatsuro Teraoka, Yurie Nishi, Akiko Sawa, Tetsuji Yamaguchi, Kaoru Tanaka, Shinya Ariyasu, Bing Wang, Shin Aoki, Megumi Sasatani, Ippei Takahashi, Akinori Morita
Inhibiting p53-dependent apoptosis by inhibitors of p53 is an effective strategy for preventing radiation-induced damage in hematopoietic lineages, while p53 and p21 also play radioprotective roles in the gastrointestinal epithelium. We previously id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f80c5904732d5ceff13879de639d816
https://doi.org/10.1158/1535-7163.c.6537741
https://doi.org/10.1158/1535-7163.c.6537741
Autor:
Shinya Ariyasu, Kenji Kamiya, Yasushi Nagata, Chihiro Yanagawa, Yurie Nishi, Bing Wang, Mitsuru Nenoi, Tetsuji Yamaguchi, Toshiya Inaba, Keiji Tanimoto, Atsushi Enomoto, Kaoru Tanaka, Yoshio Hosoi, Akinori Morita, I. Takahashi, Megumi Sasatani, Tatsuro Teraoka, Yosuke Kawate, Shin Aoki, Shohei Ujita, Akiko Sawa
Publikováno v:
Molecular Cancer Therapeutics. 17(2):432-442
Inhibiting p53-dependent apoptosis by inhibitors of p53 is an effective strategy for preventing radiation-induced damage in hematopoietic lineages, while p53 and p21 also play radioprotective roles in the gastrointestinal epithelium. We previously id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c357b9cc7ae5712599e289fb583f7c07
https://repo.lib.tokushima-u.ac.jp/111999
https://repo.lib.tokushima-u.ac.jp/111999
Publikováno v:
BIBM
Radiation therapy is one of the main treatments for cancer. However, it may cause various side effects owing to the apoptosis activity of the p53 protein in normal cells. Therefore, to avoid the side effects, it is important to protect normal cells a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::254098e75b64358ae25968163b9eef61
https://doi.org/10.1109/bibm.2018.8621142
https://doi.org/10.1109/bibm.2018.8621142
Publikováno v:
BCB
In this paper, we propose new methods to make the rankings of candidates for p53 inhibitors, considering both radioprotective function and cytotoxicity. We use features about compound's structure including fingerprints, machine learning methods and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31aeb74bba0b32a83e8f5cd4c7cefcd1
https://doi.org/10.1145/3233547.3233630
https://doi.org/10.1145/3233547.3233630
Autor:
Ujita, Shohei, Mmorita, Akinori, Aoki, Shin, Nishi, Yurie, Tatsuro, Teraoka, Sasatani, Megumi, Wang, Bing, Takahashi, Ippei, Tanaka, Kaoru, Yamakawa, Tomoaki, Nenoi, Mitsuru, Kamiya, Kenji, Inaba, Toshiya
Development of radioprotectors is a very important strategy for reducing radiation risk. We have explored compounds that target a zinc-binding site (ZBS) in p53 , and found that 5-chloro-8-quinolinol (5CHQ) has a unique p53-agonistic activity that sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::32a1c52d531d4fb593bcf1fe6e712db0
https://repo.qst.go.jp/records/72229
https://repo.qst.go.jp/records/72229
Publikováno v:
BIBM
Radiation therapy and some chemotherapeutic agents mainly target the DNA of growing cancer cells, whereas these therapies have adverse side effects, including p53-induced apoptosis of normal tissues and cells. It is considered that p53 would be a tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e57061f7c511143141e8c7da67dd5ed
https://doi.org/10.1109/bibm.2015.7359941
https://doi.org/10.1109/bibm.2015.7359941