Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Tatsuro Naganuma"'
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 2, Pp 100329- (2023)
Coordinated lipid metabolism contributes to maintaining skin homeostasis by regulating skin barrier formation, immune reactions, thermogenesis, and perception. Several reports have documented the changes in lipid composition in dermatitis, including
Externí odkaz:
https://doaj.org/article/7dd039adcd0b411992876d39ace1958e
Autor:
Keisuke Mori, Takashi Obara, Naoya Seki, Masatoshi Miyamoto, Tatsuro Naganuma, Takuya Kitamura, Akio Kihara
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 7, Pp 1104-1114 (2020)
The yeast protein Mpo1 belongs to a protein family that is widely conserved in bacteria, fungi, protozoa, and plants, and is the only protein of this family whose function has so far been elucidated. Mpo1 is an Fe2+-dependent dioxygenase that catalyz
Externí odkaz:
https://doaj.org/article/fdc2c49e2f124982962a5dc3dcb27133
Autor:
Tatsuro Naganuma, Akio Kihara
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101823 (2014)
Fatty acids (FAs) are diverse molecules, and such diversity is important for lipids to exert their functions under several environmental conditions. FA elongation occurs at the endoplasmic reticulum and produces a variety of FA species; the FA elonga
Externí odkaz:
https://doaj.org/article/14c7acd5094547a29be3d3746a45e137
Publikováno v:
Biological and Pharmaceutical Bulletin. 45:998-1007
Epithelial tissues are mainly composed of epithelial cells, covering both internal and external surfaces of our body. To maintain epithelial homeostasis, cellular functions, such as proliferation, migration, and differentiation, are flexibly regulate
Autor:
Ai Ota, Hiroya Morita, Tatsuro Naganuma, Masatoshi Miyamoto, Keisuke Jojima, Koki Nojiri, Junko Matsuda, Akio Kihara
Publikováno v:
Journal of Biological Chemistry. 299:104603
Autor:
Ari Morimoto, Keitaro Fukuda, Yoshihiro Ito, Umi Tahara, Takashi Sasaki, Aiko Shiohama, Hiroshi Kawasaki, Eiryo Kawakami, Tatsuro Naganuma, Makoto Arita, Hiroyuki Sasaki, Haruhiko Koseki, Takeshi Matsui, Masayuki Amagai
Publikováno v:
The Journal of investigative dermatology. 142(11)
TMEM79 is a predisposing gene for atopic dermatitis. Tmem79-deficient mice develop spontaneous dermatitis in a biphasic pattern. The first-phase dermatitis is unique because it occurs independent of microbiota status, whereas the second-phase dermati
Autor:
Akio Kihara, Keisuke Mori, Tatsuro Naganuma, Naoya Seki, Takuya Kitamura, Masatoshi Miyamoto, Takashi Obara
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 7, Pp 1104-1114 (2020)
J Lipid Res
J Lipid Res
The yeast protein Mpo1 belongs to a protein family that is widely conserved in bacteria, fungi, protozoa, and plants, and is the only protein of this family whose function has so far been elucidated. Mpo1 is an Fe2+-dependent dioxygenase that catalyz
Autor:
Takayuki Sassa, Tsukasa Kanetake, Akio Kihara, Shuyu Takagi, Satoko Hattori, Takuya Kitamura, Tatsuro Naganuma, Tsuyoshi Miyakawa
Publikováno v:
Journal of Biological Chemistry. 291:11676-11688
The fatty aldehyde dehydrogenase (FALDH) ALDH3A2 is the causative gene of Sjogren Larsson syndrome (SLS). To date, the molecular mechanism underlying the symptoms characterizing SLS has been poorly understood. Using Aldh3a2(-/-) mice, we found here t
Autor:
Akira Utsunomiya, Makoto Arita, Tatsuro Naganuma, Takenao Chino, Natsuko Utsunomiya, Atsushi Tokuriki, Noriyuki Suzuki, Ayako Ohara, V.H. Luong, Noritaka Oyama, Minoru Hasegawa, Koichi Saito, Kiyoshi Higashi, Daisuke Tsuruta, Manabu Sugai, Koji Sugawara
Publikováno v:
Journal of Investigative Dermatology. 140:838-849.e9
Dermokine is a chiefly skin-specific secreted glycoprotein localized in the upper epidermis, and its family consists of three splice variants in mice and five in humans. To investigate the pathophysiological impact of dermokine, we generated mice def
Publikováno v:
Biochemical journal. 465:79-87
Aldehyde dehydrogenases (ALDHs) catalyse the conversion of toxic aldehydes into non-toxic carboxylic acids. Of the 21 ALDHs in mice, it is the ALDH3 family members (ALDH3A1, ALDH3A2, ALDH3B1, ALDH3B2 and ALDH3B3) that are responsible for the removal