Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Tatsuro Ishida"'
Autor:
Makoto Nishimori, Naomi Hayasaka, Kazunori Otsui, Nobutaka Inoue, Junko Asakura, Manabu Nagao, Ryuji Toh, Tatsuro Ishida, Ken-ichi Hirata, Tomoyuki Furuyashiki, Masakazu Shinohara
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Stress has garnered significant attention as a prominent risk factor for inflammation-related diseases, particularly cardiovascular diseases (CVDs). However, the precise mechanisms underlying stress-driven CVDs remain elusive, thereby impedi
Externí odkaz:
https://doaj.org/article/87b82116fc46422dbb4882fe053c3956
Autor:
Katsuhiro Murakami, Amane Harada, Ryuji Toh, Takuya Kubo, Keiko Miwa, Jeeeun Kim, Maria Kiriyama, Takuya Iino, Youichi Nishikawa, Shin-Nosuke Uno, Kohei Akatsuchi, Manabu Nagao, Tatsuro Ishida, Ken-ichi Hirata
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract High-density lipoprotein (HDL) cholesterol efflux capacity (CEC), which is a conventional metric of HDL function, has been associated with coronary heart disease risk. However, the CEC assay requires cultured cells and takes several days to
Externí odkaz:
https://doaj.org/article/1de9aa4def1445c6b15847a2a21ee1b1
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0265637 (2022)
BackgroundRecent studies have suggested that chronic kidney disease is associated with cardiovascular disease, dementia, and frailty, all of which cause disability and early death. We investigated whether increased activity of urinary N-acetyl-β-glu
Externí odkaz:
https://doaj.org/article/34a170f4143748e3abd306e26a0c102b
Publikováno v:
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-8 (2018)
Abstracts Background Lecithin:cholesterol acyltransferase (LCAT) plays an important role in cholesterol esterification in serum. Serum LCAT activity is elevated in patients with serum high triglyceride and low high-density lipoprotein-cholesterol (HD
Externí odkaz:
https://doaj.org/article/4f01928d6eb84fec9c2029e4ef353d27
Autor:
Takuya Iino, Ryuji Toh, Manabu Nagao, Masakazu Shinohara, Amane Harada, Katsuhiro Murakami, Yasuhiro Irino, Makoto Nishimori, Sachiko Yoshikawa, Yutaro Seto, Tatsuro Ishida, Ken-ichi Hirata
Publikováno v:
Nutrients, Vol 13, Iss 9, p 3112 (2021)
Recently we established a cell-free assay to evaluate “cholesterol uptake capacity (CUC)” as a novel concept for high-density lipoprotein (HDL) functionality and demonstrated the feasibility of CUC for coronary risk stratification, although its r
Externí odkaz:
https://doaj.org/article/e0a4630b087643dcacba5b7cef4e43d5
Autor:
Shigeyasu Tsuda, Masakazu Shinohara, Toshihiko Oshita, Manabu Nagao, Nobuaki Tanaka, Takeshige Mori, Tetsuya Hara, Yasuhiro Irino, Ryuji Toh, Tatsuro Ishida, Ken-ichi Hirata
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract High-density lipoprotein (HDL) interacts with various cells, particularly macrophages, in functional cell-HDL interactions. Here, we found that HDL protein quality and lipid quality play critical roles in HDL functions. HDL fractions from he
Externí odkaz:
https://doaj.org/article/3b7d6c0118994f47908cc9a7e8a96bc3
Autor:
Manabu Nagao, Ryuji Toh, Yasuhiro Irino, Hideto Nakajima, Toshihiko Oshita, Shigeyasu Tsuda, Tetsuya Hara, Masakazu Shinohara, Tatsuro Ishida, Ken‐ichi Hirata
Publikováno v:
FEBS Open Bio, Vol 7, Iss 9, Pp 1402-1409 (2017)
Low levels of plasma high‐density lipoprotein (HDL) cholesterol are associated with an increased risk of heart failure, regardless of the presence or absence of coronary artery disease. However, the direct effects of HDL on failing myocardium have
Externí odkaz:
https://doaj.org/article/3289ada030db4e5c940b3247e80ecb3a
Autor:
Yuichiro Nagano, Hiromasa Otake, Takayoshi Toba, Koji Kuroda, Yuto Shinkura, Natsuko Tahara, Yoshiro Tsukiyama, Kenichi Yanaka, Hiroyuki Yamamoto, Akira Nagasawa, Hiroyuki Onishi, Yoichiro Sugizaki, Ryo Takeshige, Amane Harada, Katsuhiro Murakami, Maria Kiriyama, Toshihiko Oshita, Yasuhiro Irino, Hiroyuki Kawamori, Tatsuro Ishida, Ryuji Toh, Toshiro Shinke, Ken‐ichi Hirata
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 9 (2019)
Background We evaluated the importance of high‐density lipoprotein (HDL) functionality for target‐lesion revascularization in patients treated with coronary stents using a rapid cell‐free assay system to evaluate the functional capacity of HDL
Externí odkaz:
https://doaj.org/article/e136bce62f8640bca3a6be3a80b61cb8
Autor:
Tetsuya Hara, Tatsuro Ishida, Yoko Kojima, Hanayo Tanaka, Tomoyuki Yasuda, Masakazu Shinohara, Ryuji Toh, Ken-ichi Hirata
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 1, Pp 57-67 (2011)
Previous studies have shown that targeted deletion of endothelial lipase (EL) markedly increases the plasma high density lipoprotein cholesterol (HDL-C) level in mice. However, little is known about the functional quality of HDL particles after EL in
Externí odkaz:
https://doaj.org/article/84766d8ab7e14d56863af907f87dde0e
Autor:
Kenneth C-W. Yu, Christopher David, Sujata Kadambi, Andreas Stahl, Ken-Ichi Hirata, Tatsuro Ishida, Thomas Quertermous, Allen D. Cooper, Sungshin Y. Choi
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 9, Pp 1614-1623 (2004)
Both LPL and HL are synthesized in parenchymal cells, are secreted, and bind to endothelial cells. To learn where endothelial lipase (EL) is synthesized in adult animals, the localization of EL in mouse and rat liver was studied by immunohistochemica
Externí odkaz:
https://doaj.org/article/9cdf21377a3a4abca351ffbffee8eaa2