Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Tatsuo Yagura"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 109, Iss 4, Pp 573-582 (2009)
Our previous study showed that organobismuth compounds induce apoptosis in human promyelocytic leukemia cells, although solid tumor cell lines were relatively resistant. Herein, we investigated the primary cellular target of these compounds in HeLa c
Externí odkaz:
https://doaj.org/article/b7be0e5507104197887a7fe30edbc17b
Autor:
Katsuya Iuchi, Tatsuo Yagura
Publikováno v:
Toxicology in Vitro. 50:172-178
We previously showed that heterocyclic organobismuth compounds have excellent antimicrobial and antitumor potential. These compounds structurally consist of either six- or eight-membered rings. Previous research has shown that bi-chlorodibenzo[c,f][1
Autor:
Tatsuo Yagura, Katsuya Iuchi
Publikováno v:
Experimental Cell Research. 342:135-144
Ku protein is a heterodimer composed of two subunits, and is capable of both sequence-independent and sequence-specific DNA binding. The former mode of DNA binding plays a crucial role in DNA repair. The biological role of Ku protein during apoptosis
Autor:
Tatsuo Yagura, Kosuke Hashimoto, Masanori Sawa, Kamila Moor, SameerahS. Alzahrani, Hidetoshi Sato, BibinB. Andriana, Satoru Kato
Publikováno v:
Advanced Science, Engineering and Medicine. 6:889-891
Publikováno v:
Journal of Pharmacological Sciences, Vol 109, Iss 4, Pp 573-582 (2009)
Our previous study showed that organobismuth compounds induce apoptosis in human promyelocytic leukemia cells, although solid tumor cell lines were relatively resistant. Herein, we investigated the primary cellular target of these compounds in HeLa c
Publikováno v:
Biochemical Pharmacology. 76:974-986
We have synthesized novel heterocyclic organobismuth compounds that have potent antibacterial properties. In this study, we examined their anticancer activity and addressed the cellular mechanisms involved. Heterocyclic organobismuth compounds showed
Autor:
Toshiaki Kotani, Hitomi Suzuki, Fumiaki Yamao, Daisuke Nagai, Tatsuo Yagura, Kensuke Asahi, Nobumasa Kataoka
Publikováno v:
Antimicrobial Agents and Chemotherapy. 49:2729-2734
Bismuth compounds are known for their low levels of toxicity in mammals, and various types of bismuth salts have been used to treat medical disorders. As part of our program to probe this aspect of bismuth chemistry, cyclic organobismuth compounds 1
Publikováno v:
Life Sciences. 73:2335-2344
Mechanisms for hyperleptinemia elicited by a serotonin (5-hydroxytryptamine, 5-HT) precursor, 5-hydroxytryptophan (5-HTP), were investigated. 5-HTP elicited apparent increases in serum leptin levels of mice. Administration of 5-HTP did not alter expr
Publikováno v:
Cell Structure and Function. 27:117-125
In order to elucidate the mechanism controlling the biogenesis of the Golgi complex, we have studied whether the expression of a resident membrane protein p138 of the Golgi complex is dependent upon the cell cycle. The protein level of p138 in human
Publikováno v:
Plant and Cell Physiology. 41:1347-1353
The reaction center (RC) and the core (RC-LH1) complex were isolated and purified from Rhodobium marinum; together with the LH1 complex [Meckenstock et al. (1992a) FEBS Lett. 311: 128], a complete set of RC, LH1 and RC-LH1 from the same wild-type str