Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Tatsuo Tanimoto"'
Autor:
Erin Moshier, Masakatsu Kotsuma, Klaas Nicolay, Sotirios Tsimikas, Zahi A. Fayad, Jessica S. Mounessa, Esad Vucic, Sarayu Ramachandran, Karen Brown, Matthew J. Moon, James H.F. Rudd, Edward A. Fisher, Jan Bucerius, Claudia Calcagno, Michelle Roytman, James Lin, Stephen D. Dickson, Tatsuo Tanimoto, Katsumi Hayashi, Valentin Fuster
Publikováno v:
JACC: Cardiovascular Imaging. 5:819-828
Objectives The aim of this study was to noninvasively detect the anti-inflammatory properties of the novel liver X receptor agonist R211945. Background R211945 induces reversal cholesterol transport and modulates inflammation in atherosclerotic plaqu
Autor:
Naoki Terasaka, Ken Kitayama, Tadashi Koieyama, Tatsuo Tanimoto, Atsuhiro Miyazaki, Kayoko Ito, Naoyuki Maeda, Naoko Ubukata, Toshimori Inaba, Naomi Kasanuki
Publikováno v:
Atherosclerosis. 190:239-247
The objective of the present study was to determine whether a novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor, pactimibe sulfate (CS-505), could reduce atherosclerotic lesions beyond and independent of the reduction achieved by cholestero
Autor:
Tatsuo Tanimoto
Publikováno v:
Folia Pharmacologica Japonica. 129:267-270
Autor:
Tatsuo Tanimoto, Tomoyuki Fujioka, Teiichiro Koga, Naoki Terasaka, Ken Kitayama, Toshimori Inaba
Publikováno v:
European Journal of Pharmacology. 540:121-130
Pactimibe sulfate, [7-(2,2-dimethylpropanamido)-4,6-dimethyl-1-octylindolin-5-yl]acetic acid hemisulfate, a novel Acyl-coenzyme A:cholesterol acyltransferase (ACAT) inhibitor, was investigated in vitro and in vivo to characterize its potential. Pacti
Publikováno v:
Journal of Biological Chemistry. 277:42997-43001
Sphingosine 1-phosphate (S1P) and vascular endothelial growth factor (VEGF) elicit numerous biological responses including cell survival, growth, migration, and differentiation in endothelial cells mediated by the endothelial differentiation gene, a
Autor:
Yuji Saito, Yukihiro Hojo, Ryan Hoefen, Kei Yamamoto, Reto Asmis, Tatsuo Tanimoto, Christopher P. Baines, Judith Haendeler, Bradford C. Berk
Publikováno v:
Circulation Research. 91:712-718
c-Jun NH 2 -terminal kinase (JNK) is activated by a number of cellular stimuli including reactive oxygen species (ROS). Previous studies have demonstrated that fluid shear stress (flow) inhibits cytokine-induced JNK activation in endothelial cells (E
Autor:
Kazuyuki Minagawa, Shuichi Kouzuki, Toshiyuki Kamigauchi, Yoshihiro Terui, Kikuo Ishii, Hiroyoshi Tani, Tatsuo Tanimoto
Publikováno v:
The Journal of Antibiotics. 55:239-248
Stachybotrys sp. RF-7260 was found to produce stachyflins, novel anti-influenza virus agents, under solid-state fermentation conditions. Feeding DL-lysine to a culture of Stachybotrys sp. RF-7260 induced the formation of the novel compounds, SQ-02-S-
Publikováno v:
Mycoscience. 42:627-630
To recover degenerate schizostatin production in aSchizophyllum commune isolate, SANK 17785, we examined schizostatin production of 30 single-basidiospore isolates obtained from a basidiocarp of SANK 17785. One of the isolates showed high productivit
Autor:
Takahiro Yamaguchi, Kazuyuki Minagawa, Keisuke Matsushima, Tatsuo Tanimoto, Hiroyoshi Tani, Kazuhide Nomura, Yoshimi Kawamura, Shuichi Kouzuki, Kikuo Ishii, Toshiyuki Kamigauchi
Publikováno v:
The Journal of Antibiotics. 54:890-895
In the course of screening for yeast squalene synthase inhibitors, bisabosqual A was isolated from the culture broth of Stachybotrys sp. RF-7260. The related compounds bisabosquals B, C and D were also isolated from Stachybotrys ruwenzoriensis RF-685
Autor:
Tsuyoshi Hosoya, Yoshio Tsujita, Yuko Kurihara, Tatsuo Tanimoto, Kaori Onodera, Yasuyuki Takamatsu
Publikováno v:
Mycoscience. 38:305-311
In search for new zaragozic acids and their derivatives that are potent inhibitors of squalene synthase, discomycetes of the order Leotiales were cultured and their fermentation broth was assayed. Three strains in 2 unidentified species ofMollisia we