Zobrazeno 1 - 10
of 715
pro vyhledávání: '"Tatsuo Kanda"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5454 (2024)
The human genome encodes at least 500 protein kinases, and among them, there are at least 90 tyrosine kinases [...]
Externí odkaz:
https://doaj.org/article/240040dca2624f34b6e15d45b23d9214
Autor:
Mitsuhiko Moriyama, Tatsuo Kanda, Yutaka Midorikawa, Hiroshi Matsumura, Ryota Masuzaki, Hitomi Nakamura, Masahiro Ogawa, Shunichi Matsuoka, Toshikatu Shibata, Motomi Yamazaki, Kazumichi Kuroda, Hisashi Nakayama, Tokio Higaki, Kazunori Kanemaru, Toshio Miki, Masahiko Sugitani, Tadatoshi Takayama
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-21 (2022)
Abstract Recently, we reported that extent of proliferation of atypical hepatocytes (atypical hepatocytes) was most important histological risk factor for development of hepatocellular carcinoma (HCC) from chronic hepatitis C or liver cirrhosis. Here
Externí odkaz:
https://doaj.org/article/27e6f2d8468c4fb0b2d055a0dbb1b956
Autor:
Rei Hirano, Tatsuo Kanda, Masayuki Honda, Shuhei Arima, Mai Totsuka, Ryota Masuzaki, Shini Kanezawa, Reina Sasaki-Tanaka, Naoki Matsumoto, Hiroaki Yamagami, Tomotaka Ishii, Masahiro Ogawa, Shuzo Nomura, Mariko Fujisawa, Kei Saito, Masaharu Takahashi, Hiroaki Okamoto, Hirofumi Kogure
Publikováno v:
Reports, Vol 6, Iss 4, p 55 (2023)
Hepatitis E virus (HEV) genotypes 3 and 4 are zoonotic strains that are primarily transmitted through the consumption of undercooked pork or game meat. They also cause asymptomatic infections, acute hepatitis, acute-on-chronic liver failure, chronic
Externí odkaz:
https://doaj.org/article/5797b42f91c5498b914ee10db476e080
Autor:
Like Zhang, Xia Jiang, Guiqi Wang, Tatsuo Kanda, Osamu Yokosuka, Congjie Zhai, Lei Zhang, Peng Liu, Zengren Zhao, Zhongxin Li
Publikováno v:
Infectious Agents and Cancer, Vol 17, Iss 1, Pp 1-12 (2022)
Abstract Background The most common type of cancer of the digestive system is hepatocellular carcinoma. In China, many patients harbour HBV. The lin28B/Let-7c/MYC axis is associated with the occurrence of many cancers. Therefore, we aimed to illumina
Externí odkaz:
https://doaj.org/article/8d62706f8c8148189eb8a47d2d0b9138
Autor:
Tatsuo Kanda, Reina Sasaki-Tanaka, Naoki Matsumoto, Shuhei Arima, Shini Kanezawa, Masayuki Honda, Mai Totsuka, Tomotaka Ishii, Ryota Masuzaki, Masahiro Ogawa, Hiroaki Yamagami, Hirofumi Kogure
Publikováno v:
Medicina, Vol 59, Iss 9, p 1506 (2023)
Background and Objectives: Muscle cramps are often observed in patients with liver diseases, especially advanced liver fibrosis. The exact prevalence of muscle cramps in outpatients with liver diseases in Japan is unknown. Patients and Methods: This
Externí odkaz:
https://doaj.org/article/09727aa6ab524cb78c2e7d9fc3e2e119
Autor:
Kazufumi Kobayashi, Sadahisa Ogasawara, Aya Takahashi, Yuya Seko, Hidemi Unozawa, Rui Sato, Shunji Watanabe, Michihisa Moriguchi, Naoki Morimoto, Satoshi Tsuchiya, Kenji Iwai, Masanori Inoue, Keita Ogawa, Takamasa Ishino, Terunao Iwanaga, Takafumi Sakuma, Naoto Fujita, Hiroaki Kanzaki, Keisuke Koroki, Masato Nakamura, Naoya Kanogawa, Soichiro Kiyono, Takayuki Kondo, Tomoko Saito, Ryo Nakagawa, Eiichiro Suzuki, Yoshihiko Ooka, Shingo Nakamoto, Akinobu Tawada, Tetsuhiro Chiba, Makoto Arai, Tatsuo Kanda, Hitoshi Maruyama, Kengo Nagashima, Jun Kato, Norio Isoda, Takeshi Aramaki, Yoshito Itoh, Naoya Kato
Publikováno v:
Liver Cancer, Pp 1-13 (2021)
Background and Aims: The prognosis of patients with advanced hepatocellular carcinoma (HCC) is expected to improve as multiple molecular target agents (MTAs) are now available. However, the impact of the availability of sequential MTAs has not been f
Externí odkaz:
https://doaj.org/article/3d27bd60476f43d0ad39fa2137391db5
Autor:
Yuko Kusakabe, Tetsuhiro Chiba, Motohiko Oshima, Shuhei Koide, Ola Rizq, Kazumasa Aoyama, Junjie Ao, Tatsuya Kaneko, Hiroaki Kanzaki, Kengo Kanayama, Takahiro Maeda, Tomoko Saito, Ryo Nakagawa, Kazufumi Kobayashi, Soichiro Kiyono, Masato Nakamura, Sadahisa Ogasawara, Eiichiro Suzuki, Shingo Nakamoto, Shin Yasui, Rintaro Mikata, Ryosuke Muroyama, Tatsuo Kanda, Hitoshi Maruyama, Jun Kato, Naoya Mimura, Anqi Ma, Jian Jin, Yoh Zen, Masayuki Otsuka, Atsushi Kaneda, Atsushi Iwama, Naoya Kato
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Both EZH2 and its homolog EZH1 function as histone H3 Lysine 27 (H3K27) methyltransferases and repress the transcription of target genes. Dysregulation of H3K27 trimethylation (H3K27me3) plays an important role in the development and progres
Externí odkaz:
https://doaj.org/article/8eb58697caf4466e8a01b8253f2d212f
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-8 (2021)
Abstract Hepatocellular carcinoma (HCC) is one of the most common malignancy-related deaths. p53 mutation in HCC associates with worse clinicopathologic features including therapeutic limitation. A combination of targeted therapy may have some advant
Externí odkaz:
https://doaj.org/article/3e23d0b8a3bc45bab032fe4d6ec552a6
Autor:
Reina Sasaki-Tanaka, Toshikatsu Shibata, Mitsuhiko Moriyama, Hirofumi Kogure, Asuka Hirai-Yuki, Hiroaki Okamoto, Tatsuo Kanda
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9708 (2023)
The hepatitis A virus (HAV) infection causes acute hepatitis. HAV also induces acute liver failure or acute-on-chronic liver failure; however, no potent anti-HAV drugs are currently available in clinical situations. For anti-HAV drug screening, more
Externí odkaz:
https://doaj.org/article/2f1e0ef5a2d14cd083b9ff621ce5c65e
Autor:
Tatsuo Kanda
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6218 (2023)
In this Special Issue, “Molecular Mechanism of Chronic Viral and Non-viral Liver Diseases”, invaluable articles have been published [...]
Externí odkaz:
https://doaj.org/article/9316cb98507b46bd85b31bc19e63d991