Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Tatsuo Itakura"'
Autor:
Maria Fernanda Suarez, Tatsuo Itakura, Satyabrata Pany, Shinwu Jeong, Shravan K. Chintala, Michael B. Raizman, Steven Riesinger, Tsvetelina Lazarova, José Echenique, Horacio M. Serra, W. Daniel Stamer, M. Elizabeth Fini
Publikováno v:
Stresses, Vol 3, Iss 3, Pp 629-652 (2023)
Elevated intraocular pressure (IOP), the major risk factor for glaucoma, is caused by decreased outflow through the trabecular meshwork (TM). The pathophysiology of ocular hypertension has been linked to stress pathways, including fibrosis, calcifica
Externí odkaz:
https://doaj.org/article/d7b8cb97eb0046e480769cd972be43a1
Autor:
Andrew Webster, Shravan K Chintala, Jasmine Kim, Michelle Ngan, Tatsuo Itakura, Noorjahan Panjwani, Pablo Argüeso, Joseph T Barr, Shinwu Jeong, M Elizabeth Fini
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204288 (2018)
Water soluble "vital" dyes are commonly used clinically to evaluate health of the ocular surface; however, staining mechanisms remain poorly understood. Recent evidence suggests that sublethal damage stimulates vital dye uptake by individual living c
Externí odkaz:
https://doaj.org/article/bd50d6f17f2341efb6b31a56250f4033
Autor:
Nitin Patel, Tatsuo Itakura, Shinwu Jeong, Chun-Peng Liao, Pradip Roy-Burman, Ebrahim Zandi, Susan Groshen, Jacek Pinski, Gerhard A Coetzee, Mitchell E Gross, M Elizabeth Fini
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117758 (2015)
Prostate cancer (PCa) is the second-leading cause of cancer-related mortality, after lung cancer, in men from developed countries. In its early stages, primary tumor growth is dependent on androgens, thus generally can be controlled by androgen depri
Externí odkaz:
https://doaj.org/article/ffbac6972cdd427fb5688afa9e5b89dc
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57843 (2013)
Members of the large G protein-coupled receptor (GPCR) clan are implicated in many physiological and disease processes, making them important therapeutic drug targets. In the present study, we follow up on results of a pilot study suggesting a functi
Externí odkaz:
https://doaj.org/article/30505addeabd4fa083ea197500693da2
Autor:
Jose M. Gonzalez, Ted S. Acott, W. Daniel Stamer, James C. Tan, Shravan K. Chintala, Tatsuo Itakura, Yuchen Wang, Andrew Webster, Cheryl M. Craft, M. Elizabeth Fini, Shinwu Jeong, Janice A. Vranka, Kirill A. Martemyanov, Maria Sibug Saber
Publikováno v:
J Ocul Pharmacol Ther
Purpose: GPR158 is a newly characterized family C G-protein-coupled receptor, previously identified in functional screens linked with biological stress, including one for susceptibility to ocular hypertension/glaucoma induced by glucocorticoid stress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::954c7801002d2c3084e30bb7f6bd3b09
https://doi.org/10.1089/jop.2018.0135
https://doi.org/10.1089/jop.2018.0135
Autor:
Tatsuo Itakura, Corinne Ponchel, Aditi Bauskar, M. Elizabeth Fini, Shinwu Jeong, Adriana J. LaGier, Gabriel M Gordon, Nitin Patel
Publikováno v:
Wound Repair and Regeneration. 24:89-99
The goal of this study was to develop and validate a simple but quantitative cell-based assay to identify compounds that might be used pharmaceutically to give tissue repair a more regenerative character. The cornea was used as the model, and some sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::556d9ab92a17c7ec3b9e0d8d92ea8909
https://doi.org/10.1111/wrr.12390
https://doi.org/10.1111/wrr.12390
Autor:
Charles W. Flowers, Valerie Yu, Dhruva Bhattacharya, Mingwu Wang, Shravan K. Chintala, Tatsuo Itakura, Joseph T. Barr, Andrew Webster, M. Elizabeth Fini, Aditi Bauskar, Shinwu Jeong, Mark R. Wilson, Martin Heur
Publikováno v:
The ocular surface. 16(4)
Purpose To investigate the relationship between tear concentration of the homeostatic protein clusterin (CLU) and dry eye signs and symptoms, and to characterize tear CLU protein. Methods Two independent studies were conducted, one in Tucson (44 subj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be01c5c3f9ecfa7d1af23243ec1d2792
https://pubmed.ncbi.nlm.nih.gov/30077709
https://pubmed.ncbi.nlm.nih.gov/30077709
Autor:
Michelle Ngan, Jasmine Kim, Shinwu Jeong, Pablo Argüeso, Andrew Webster, Shravan K. Chintala, Tatsuo Itakura, Joseph T. Barr, M. Elizabeth Fini, Noorjahan Panjwani
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204288 (2018)
“Vital” dyes such as fluorescein and rose bengal are used clinically to evaluate ocular surface health; however, staining mechanisms remain poorly understood. Recent evidence suggests that sublethal cell damage stimulates fluorescein dye uptake.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fac5fd342532e0b00d9377fe6d8afa2f
http://europepmc.org/articles/PMC6179211?pdf=render
http://europepmc.org/articles/PMC6179211?pdf=render
Autor:
Stephen G. Schwartz, W. Daniel Stamer, M. Elizabeth Fini, Tatsuo Itakura, Nitin Patel, Francis W. Price, Marianne O. Price, Xiaoyi Gao, Shinwu Jeong, Rohit Varma
Elevation of intraocular pressure (IOP) due to therapeutic use of glucocorticoids is called steroid-induced ocular hypertension (SIOH); this can lead to steroid-induced glaucoma (SIG). Glucocorticoids initiate signaling cascades ultimately affecting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09166f0d5c428fb430a6a684fa9175a7
https://europepmc.org/articles/PMC5237612/
https://europepmc.org/articles/PMC5237612/
Autor:
Keisuke Hikosaka, Tadayoshi Uezato, Bo Wang, Wataru Kimura, Xiao Dong Xue, Naoyuki Miura, Mohammad Tofael Kabir Sharkar, Zhi Yang, Tomoki Tamakoshi, Tatsuo Itakura, Abhishek Chandra
Publikováno v:
Life Sciences. 87:17-25
Aims Foxp2 is expressed in the lung during mouse development. A monoclonal anti-mouse Foxp2 antibody was created to determine the expression pattern in the developing lung. Next, transcriptional control of two lung genes, CC10 and surfactant protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::799e781715c29ad56fc51219c8fd93c2
https://doi.org/10.1016/j.lfs.2010.05.009
https://doi.org/10.1016/j.lfs.2010.05.009