Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tatsuo Adachi"'
Autor:
Tatsuo Adachi, Yoshikazu Nakamura
Publikováno v:
Molecules, Vol 24, Iss 23, p 4229 (2019)
Aptamers are short, single-stranded oligonucleotides that bind to specific target molecules. The shape-forming feature of single-stranded oligonucleotides provides high affinity and excellent specificity toward targets. Hence, aptamers can be used as
Externí odkaz:
https://doaj.org/article/704aba8471b348dc85d7870797f828d1
Publikováno v:
Nature Computational Science. 2:378-386
Nucleic acid aptamers are generated by an in vitro molecular evolution method known as systematic evolution of ligands by exponential enrichment (SELEX). Various candidates are limited by actual sequencing data from an experiment. Here we developed R
Autor:
Yoshikazu Nakamura, Tatsuo Adachi
Publikováno v:
Molecules, Vol 24, Iss 23, p 4229 (2019)
Molecules
Molecules
Aptamers are short, single-stranded oligonucleotides that bind to specific target molecules. The shape-forming feature of single-stranded oligonucleotides provides high affinity and excellent specificity toward targets. Hence, aptamers can be used as
Autor:
Aya Yokota, Yoshikazu Nakamura, Michiaki Hamada, Ryoga Ishida, Hidehito Yoshihara, Kazuteru Aoki, Tatsuo Adachi
Publikováno v:
Nucleic Acids Research
Aptamers are short single-stranded RNA/DNA molecules that bind to specific target molecules. Aptamers with high binding-affinity and target specificity are identified using an in vitro procedure called high throughput systematic evolution of ligands
Publikováno v:
長崎国際大学論叢 = Nagasaki International University Review. 15:175-183
カイコ(Bombyx mori)の幼虫体液中にはカイコ由来培養細胞の増殖を抑制する活性があることを見出した。また、カイコ体液によって増殖を阻害された細胞中には脂肪滴の形成が認められた。
Autor:
Takefumi Kuranaga, Kenji Hamase, Kenichi Ishii, Tatsuo Adachi, Masayuki Inoue, Manabu Souma, Jyunichiro Yasukawa, Atmika Paudel, Makoto Urai, Motoki Murai, Hiroshi Tomoda, Hiroki Kurihara, Jie Su, Hiroshi Hamamoto, Takashi Katsu, Ryuji Uchida, Maki K. Yamada, Takuya Kaji, Kazuhisa Sekimizu
Publikováno v:
Nature Chemical Biology. 11:127-133
To obtain therapeutically effective new antibiotics, we first searched for bacterial culture supernatants with antimicrobial activity in vitro and then performed a secondary screening using the silkworm infection model. Through further purification o
Autor:
Yutaka Suzuki, Kenichi Ishii, Hiroshi Hamamoto, Kazuhisa Sekimizu, Jyunichiro Yasukawa, Tatsuo Adachi
Publikováno v:
Infection and Immunity. 82:1500-1510
We performed a genomewide analysis using a next-generation sequencer to investigate the effect of pulmonary surfactant on gene expression in Staphylococcus aureus , a clinically important opportunistic pathogen. RNA sequence (RNA-seq) analysis of bac
Publikováno v:
Journal of Invertebrate Pathology. 117:61-67
Injection of culture supernatant of Serratia marcescens, a Gram-negative bacterium pathogenic to a wide range of host animals including insects and mammals, into the hemolymph of silkworm (Bombyx mori) larvae led to continuous flow of the hemolymph (
Publikováno v:
Drug discoveriestherapeutics. 9(4)
Some peptides that are highly conserved between insects and mammals have anti-tumor action. Screening for inhibitors of cell growth from animal fluids may provide useful clues to anti-tumor drugs. Inducers of autophagy also have anti-tumor activity.
Autor:
Kiminori Itoh, Kyoichi Sasaki, Hideki Kawai, Tatsuo Adachi, Xiao Min Chen, Masayuki Murabayashi, Toshihiko Nagamura
Publikováno v:
Talanta. 65:1071-1077
A composite optical waveguide (OWG) composed of a 10-18nm thick titanium dioxide (TiO(2)) film sputtered on a conventional K(+)-doped optical waveguide was first applied to detect transient absorption of organic dyes in ultrathin polymer films upon e