Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Tatsuji Matsuoka"'
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240673 (2020)
Some monoclonal antibodies undergo liquid-liquid phase separation owing to self-attractive associations involving electrostatic and other soft interactions, thereby rendering monoclonal antibodies unsuitable as therapeutics. To mitigate the phase sep
Externí odkaz:
https://doaj.org/article/aa611d665e184356865ac1643d7f6f33
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 10, p e0240673 (2020)
PLoS ONE, Vol 15, Iss 10, p e0240673 (2020)
Some monoclonal antibodies undergo liquid-liquid phase separation owing to self-attractive associations involving electrostatic and other soft interactions, thereby rendering monoclonal antibodies unsuitable as therapeutics. To mitigate the phase sep
Autor:
Nobuaki Watanabe, Shin-ichi Inaba, Chizuko Yahara, Kazuishi Kubota, Masakazu Tamura, Kiyoaki Yonesu, Futoshi Nara, Tomohiro Honda, Tatsuji Matsuoka
Publikováno v:
The Journal of Biological Chemistry
CS-0777 is a selective sphingosine 1-phosphate (S1P) receptor 1 modulator with potential benefits in the treatment of autoimmune diseases, including multiple sclerosis. CS-0777 is a prodrug that requires phosphorylation to an active S1P analog, simil
Autor:
Hidehiko Furukawa, Hara Ayako, Makoto Yamashita, Tatsuji Matsuoka, Kazuishi Kubota, Shuku Yoshida, Chigusa Yoshimura, Kimihisa Ichikawa, Yasuteru Iijima, Junko Kawaguchi, Kaori Nakahara, Toshiaki Ohtsuka, Yohei Ozeki, Hideyuki Haruyama, Yoko Fujita
Publikováno v:
Journal of Biological Chemistry. 279:37832-37841
The 2-5A system is one of the major pathways for antiviral and antitumor functions that can be induced by interferons (IFNs). The 2-5A system is modulated by 5'-triphosphorylated, 2',5'-phosphodiester-linked oligoadenylates (2-5A), which are synthesi
Autor:
Tomoko Yoneyama-Takazawa, Takamitsu Sasaki, Kazuishi Kubota, Toshiyuki Kosaka, Yorihisa Tanaka, Tatsuji Matsuoka, Ikuya Sato
Publikováno v:
Journal of Mass Spectrometry. 38:1281-1287
We have developed a method for protein identification with peptide mass fingerprinting and sequence tagging using nano liquid chromatography (LC)/Fourier transform ion cyclotron resonance mass spectrometry (FTICR-MS). To achieve greater sensitivity,
Publikováno v:
Mycoscience. 36:193-197
Thetrans-4-hydroxy-(l)-proline productivity and morphological characteristics of strains isolated from two different conidium-producing structures inClonostachys cylindrospora were compared.trans-4-Hydroxy-(l)-proline was found to be produced only by
Autor:
Gerald W. Hart, Jeffrey C. Culhane, Felicia A. Etzkorn, Natasha E. Zachara, Gai Yan, Zhi Xie, Jiang Qian, Heng Zhu, Seth Blackshaw, Mary Katherine Tarrant, Hee Sool Rho, Yoshitaka Ichikawa, Yu Lin Jiang, Jun Seop Jeong, Christopher Gross, Tatsuji Matsuoka, Philip A. Cole
Publikováno v:
Nature chemical biology
Protein serine-threonine kinase casein kinase II (CK2) is involved in a myriad of cellular processes including cell growth and proliferation through its phosphorylation of hundreds of substrates, yet how CK2 function is regulated is poorly understood
Autor:
Kenji Mori, Tatsuji Matsuoka, Hiromasa Kiyota, Akira Horiguchi, Takeshi Kitahara, Hitoshi Kurata, Yasuhiro Warita
Publikováno v:
ChemInform. 25
An efficient two-step procedure to prepare conjugated dienes from allylic alcohols is developed without the formation of regioisomers and rearranged products
Autor:
Nobufusa Serizawa, Tatsuji Matsuoka
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1084:35-40
Pravastatin (CS-514) is a tissue selective inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (EC 1.1.1.34), a key enzyme in cholesterol biosysthesis. This compound is obtained by hydroxylation of ML-236B (mevastatin) in Streptomyces carbop
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 59:555-557
Studies were done on fermentative production of hydroxyproline, a useful chiral source of the side chain moiety of carbapenems. Various microorganisms were screened using an automatic screening-robot system, AminoQuant (Hewlett-Packard), and we found