Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Tatsuhiko, Ozawa"'
Autor:
Abdul Hayee, Eiji Kobayashi, Chihiro Motozono, Hiroshi Hamana, Ha Thi Viet My, Takuya Okada, Naoki Toyooka, Satoshi Yamaguchi, Tatsuhiko Ozawa, Hiroyuki Kishi
Publikováno v:
Cells, Vol 13, Iss 20, p 1711 (2024)
The MHC class I-related 1 (MR1) molecule is a non-polymorphic antigen-presenting molecule that presents several metabolites to MR1-restricted T cells, including mucosal-associated invariant T (MAIT) cells. MR1 ligands bind to MR1 molecules by forming
Externí odkaz:
https://doaj.org/article/686f5558a3f74a8d8717db0ad332b392
Autor:
Yuka Hayashi, Kazuto Tajiri, Tatsuhiko Ozawa, Kiyohiko Angata, Takashi Sato, Akira Togayachi, Izuru Nagashima, Hiroki Shimizu, Aiko Murayama, Nozomu Muraishi, Hisashi Narimatsu, Ichiro Yasuda
Publikováno v:
Medicina, Vol 60, Iss 8, p 1334 (2024)
Background and Objectives: The measurement of hepatitis B surface antigen (HBsAg) is essential for managing chronic hepatitis B virus infection (CHB). HBsAg consists of three different surface envelope proteins: large, middle, and small HB surface pr
Externí odkaz:
https://doaj.org/article/d225c1ca822a4cefa9945607cf336618
Autor:
Kohdai Yamada, Fumiya Soga, Soh Tokunaga, Hikaru Nagaoka, Tatsuhiko Ozawa, Hiroyuki Kishi, Eizo Takashima, Tatsuya Sawasaki
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Polypeptide tags and biotin labelling technologies are widely used for protein analyses in biochemistry and cell biology. However, many peptide tag epitopes contain lysine residues (or amino acids) that are masked after biotinylation. Here,
Externí odkaz:
https://doaj.org/article/2aa11100aa0b4e0fb6b83a1af538ddcd
Autor:
Hiroyuki Takeda, Tatsuhiko Ozawa, Hiroki Zenke, Yoh Ohnuki, Yuri Umeda, Wei Zhou, Honoka Tomoda, Akihiko Takechi, Kimiyoshi Narita, Takaaki Shimizu, Takuya Miyakawa, Yuji Ito, Tatsuya Sawasaki
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
The VNAR (Variable New Antigen Receptor) is the smallest single-domain antibody derived from the variable domain of IgNAR of cartilaginous fishes. Despite its biomedical and diagnostic potential, research on VNAR has been limited due to the difficult
Externí odkaz:
https://doaj.org/article/a00f4a3c1cfb4e7bb5f0d140f48f362c
Autor:
Takamasa Katagiri, Jorge Luis Espinoza, Mizuho Uemori, Honoka Ikeda, Kohei Hosokawa, Ken Ishiyama, Takeshi Yoroidaka, Tatsuya Imi, Hiroyuki Takamatsu, Tatsuhiko Ozawa, Hiroyuki Kishi, Yasuhiko Yamamoto, Mahmoud Ibrahim Elbadry, Yoshinori Yoshida, Kazuhisa Chonabayashi, Katsuto Takenaka, Koichi Akashi, Yasuhito Nannya, Seishi Ogawa, Shinji Nakao
Publikováno v:
eJHaem, Vol 3, Iss 3, Pp 669-680 (2022)
Abstract The phenotypic changes in hematopoietic stem progenitor cells (HSPCs) with somatic mutations of malignancy‐related genes in patients with acquired aplastic anemia (AA) are poorly understood. As our initial study showed increased CXCR4 expr
Externí odkaz:
https://doaj.org/article/d29be8cd58114bf5b769d39c97fb15bd
Autor:
Tatsuhiko Ozawa, Hideki Tani, Yuki Anraku, Shunsuke Kita, Emiko Igarashi, Yumiko Saga, Noriko Inasaki, Hitoshi Kawasuji, Hiroshi Yamada, so-Ichiro Sasaki, Mayu Somekawa, Jiei Sasaki, Yoshihiro Hayakawa, Yoshihiro Yamamoto, Yoshitomo Morinaga, Nobuyuki Kurosawa, Masaharu Isobe, Hideo Fukuhara, Katsumi Maenaka, Takao Hashiguchi, Hiroyuki Kishi, Isao Kitajima, Shigeru Saito, Hideki Niimi
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Many potent neutralizing SARS-CoV-2 antibodies have been developed and used for therapies. However, the effectiveness of many antibodies has been reduced against recently emerging SARS-CoV-2 variants, especially the Omicron variant. We identified a h
Externí odkaz:
https://doaj.org/article/8f1dc584acce4456861e83257e43534d
Autor:
Eiji Kobayashi, Yusuke Kamihara, Miho Arai, Akinori Wada, Shohei Kikuchi, Ryo Hatano, Noriaki Iwao, Takeshi Susukida, Tatsuhiko Ozawa, Yuichi Adachi, Hiroyuki Kishi, Nam H. Dang, Taketo Yamada, Yoshihiro Hayakawa, Chikao Morimoto, Tsutomu Sato
Publikováno v:
Cells, Vol 12, Iss 16, p 2059 (2023)
Chimeric-antigen-receptor (CAR) T-cell therapy for CD19-expressing B-cell malignancies is already widely adopted in clinical practice. On the other hand, the development of CAR-T-cell therapy for T-cell malignancies is in its nascent stage. One of th
Externí odkaz:
https://doaj.org/article/1ec32c8167b84f72b40d5d1c2b7c58d2
Autor:
Shohei Kikuchi, Akinori Wada, Yusuke Kamihara, Kosuke Okazaki, Paras Jawaid, Mati Ur Rehman, Eiji Kobayashi, Takeshi Susukida, Tomoki Minemura, Yoshimi Nabe, Noriaki Iwao, Tatsuhiko Ozawa, Ryo Hatano, Mitsugu Yamada, Hiroyuki Kishi, Yuji Matsuya, Mineyuki Mizuguchi, Yoshihiro Hayakawa, Nam H. Dang, Yasumitsu Sakamoto, Chikao Morimoto, Tsutomu Sato
Publikováno v:
Cells, Vol 12, Iss 7, p 1100 (2023)
DPP8/9 inhibition induces either pyroptotic or apoptotic cell death in hematological malignancies. We previously reported that treatment with the DPP8/9 inhibitor 1G244 resulted in apoptotic cell death in myeloma, and our current study further evalua
Externí odkaz:
https://doaj.org/article/97715b8185fb4d6d8d5fbfbf732d6cff
Autor:
Hideki Tani, Miyuki Kimura, Long Tan, Yoshihiro Yoshida, Tatsuhiko Ozawa, Hiroyuki Kishi, Shuetsu Fukushi, Masayuki Saijo, Kaori Sano, Tadaki Suzuki, Hitoshi Kawasuji, Akitoshi Ueno, Yuki Miyajima, Yasutaka Fukui, Ippei Sakamaki, Yoshihiro Yamamoto, Yoshitomo Morinaga
Publikováno v:
Virology Journal, Vol 18, Iss 1, Pp 1-10 (2021)
Abstract Background SARS-CoV-2 is a novel coronavirus that emerged in 2019 and is now classified in the genus Coronavirus with closely related SARS-CoV. SARS-CoV-2 is highly pathogenic in humans and is classified as a biosafety level (BSL)-3 pathogen
Externí odkaz:
https://doaj.org/article/9678dbea64ed41378bfd3ca4c8b2dedc
Autor:
Yuta Hamamoto, Kazuhisa Ouhara, Syuichi Munenaga, Mikio Shoji, Tatsuhiko Ozawa, Jyunzo Hisatsune, Isamu Kado, Mikihito Kajiya, Shinji Matsuda, Toshihisa Kawai, Noriyoshi Mizuno, Tsuyoshi Fujita, Shintaro Hirata, Kotaro Tanimoto, Koji Nakayama, Hiroyuki Kishi, Eiji Sugiyama, Hidemi Kurihara
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-15 (2020)
Abstract Background Porphyromonas gingivalis (Pg) infection causes periodontal disease and exacerbates rheumatoid arthritis (RA). It is reported that inoculation of periodontopathogenic bacteria (i.e., Pg) can alter gut microbiota composition in the
Externí odkaz:
https://doaj.org/article/deb727fd6e114bc2903d27401e179854