Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Tatsiana, Castor"'
Autor:
Tobias Harm, Xiaoqing Fu, Moritz Frey, Kristina Dittrich, Adrian Brun, Tatsiana Castor, Oliver Borst, Karin Anne Lydia Müller, Tobias Geisler, Dominik Rath, Michael Lämmerhofer, Meinrad Paul Gawaz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Coronary artery disease (CAD) often leads to adverse events resulting in significant disease burdens. Underlying risk factors often remain inapparent prior to disease incidence and the cardiovascular (CV) risk is not exclusively explained by
Externí odkaz:
https://doaj.org/article/93ab7b9776024ab59fb957d8bedb2885
Autor:
Anne-Katrin Rohlfing, Kyra Kolb, Manuel Sigle, Melanie Ziegler, Alexander Bild, Patrick Münzer, Jessica Sudmann, Valerie Dicenta, Tobias Harm, Mailin-Christin Manke, Sascha Geue, Marcel Kremser, Madhumita Chatterjee, Chunguang Liang, Hendrik von Eysmondt, Thomas Dandekar, David Heinzmann, Manina Günter, Saskia von Ungern-Sternberg, Manuela Büttcher, Tatsiana Castor, Stine Mencl, Friederike Langhauser, Katharina Sies, Diyaa Ashour, Mustafa Caglar Beker, Michael Lämmerhofer, Stella E. Autenrieth, Tilman E. Schäffer, Stefan Laufer, Paulina Szklanna, Patricia Maguire, Matthias Heikenwalder, Karin Anne Lydia Müller, Dirk M. Hermann, Ertugrul Kilic, Ralf Stumm, Gustavo Ramos, Christoph Kleinschnitz, Oliver Borst, Harald F. Langer, Dominik Rath, Meinrad Gawaz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
ACKR3 is a critical regulator of platelet-mediated thrombosis and organ injury following ischemia/reperfusion. Platelet ACKR3 surface expression is independently associated with all-cause mortality in patients with cardiovascular diseases.
Externí odkaz:
https://doaj.org/article/bff45f142b4844968bc8a69ceae8231a
Autor:
Tobias Harm, Moritz Frey, Kristina Dittrich, Andreas Goldschmied, Anne-Katrin Rohlfing, Xiaoqing Fu, Adrian Brun, Tatsiana Castor, Dominik Rath, Karin Müller, Michael Lammerhofer, Meinrad Gawaz
Publikováno v:
Thrombosis and Haemostasis. 123:585-596
Background Platelets are key players in the pathophysiology of coronary artery disease (CAD) and platelet hyperreactivity leads to increased risk of developing adverse cardiovascular events. Further, significant changes in the platelet lipidome occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74fe9399460d93efc9e1fecda9319902
https://doi.org/10.1055/s-0043-1764353
https://doi.org/10.1055/s-0043-1764353
Autor:
Carolin, Langnau, Henrik, Janing, Hüseyin, Kocaman, Sarah, Gekeler, Manina, Günter, Álvaro, Petersen-Uribe, Philippa, Jaeger, Barbara, Koch, Klaus-Peter, Kreisselmeier, Tatsiana, Castor, Dominik, Rath, Meinrad Paul, Gawaz, Stella E, Autenrieth, Karin Anne Lydia, Mueller
Publikováno v:
Biomarkers. 28:97-110
Patients with cardiovascular disease (CVD) and acute SARS-CoV-2 infection might show an altered immune response during COVID-19.Twenty-three patients with CVD and SARS-CoV-2 infection were prospectively enrolled and received a cardiological assessmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad6cb747a20899ae3eae39bd13581a7
https://doi.org/10.1080/1354750x.2022.2148745
https://doi.org/10.1080/1354750x.2022.2148745
Autor:
Ioana Alesutan, Jakob Voelkl, Martina Feger, Denise V. Kratschmar, Tatsiana Castor, Sobuj Mia, Michael Sacherer, Robert Viereck, Oliver Borst, Christina Leibrock, Meinrad Gawaz, Makoto Kuro-o, Stefan Pilz, Andreas Tomaschitz, Alex Odermatt, Burkert Pieske, Carsten A. Wagner, Florian Lang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Vascular calcification resulting from hyperphosphatemia is a major determinant of mortality in chronic kidney disease (CKD). Vascular calcification is driven by aldosterone-sensitive osteogenic transformation of vascular smooth muscle cells
Externí odkaz:
https://doaj.org/article/c635e27a35b04458b69aff88f7a050b4
Autor:
Annalena Fink, Anne-Katrin Rohlfing, Valerie Dicenta, David Schaale, Marcel Kremser, Zoi Laspa, Manuel Sigle, Xiaoqing Fu, Andreas Pelzer, Melina Fischer, Patrick Münzer, Tatsiana Castor, Karin Anne Lydia Müller, Oliver Borst, Michael Lämmerhofer, Meinrad Paul Gawaz
Publikováno v:
Thrombosis and Haemostasis.
Introduction Hemolysis results in release of free hemoglobin and hemin liberation from erythrocytes. Hemin has been described to induce platelet activation and to trigger thrombosis. Methods We evaluated the effect of hemin on platelet function and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60f88d58e50775ee3e58611d3f7d5a0e
https://doi.org/10.1055/s-0043-1768057
https://doi.org/10.1055/s-0043-1768057
Autor:
Sabina Honisch, Birgit Fehrenbacher, Aleksandra Lebedeva, Ioana Alesutan, Tatsiana Castor, Saad Alkahtani, Saud Alarifi, Martin Schaller, Christos Stournaras, Florian Lang
Publikováno v:
Neurosignals, Vol 23, Iss 1, Pp 1-10 (2015)
Background: Chorein, a protein supporting activation of phosphoinositide 3 kinase (PI3K), participates in the regulation of actin polymerization and cell survival. A loss of function mutation of the chorein encoding gene VPS13A (vacuolar protein sort
Externí odkaz:
https://doaj.org/article/f84d3d88d30443cd83e3d0d263f4ec91
Autor:
Martina Feger, Ioana Alesutan, Tatsiana Castor, Sobuj Mia, Katharina Musculus, Jakob Voelkl, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 37, Iss 3, Pp 955-964 (2015)
Background/Aims: Consequences of obstructive nephropathy include tissue fibrosis, a major pathophysiological mechanism contributing to development of end-stage renal disease. Transforming growth factor β 1 (Tgfβ1) is involved in the progression of
Externí odkaz:
https://doaj.org/article/317261a53bdf4e8897ad624f59e20dac
SGK1-Sensitive Regulation of Cyclin-Dependent Kinase Inhibitor 1B (p27) in Cardiomyocyte Hypertrophy
Autor:
Jakob Voelkl, Tatsiana Castor, Katharina Musculus, Robert Viereck, Sobuj Mia, Martina Feger, Ioana Alesutan, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 37, Iss 2, Pp 603-614 (2015)
Background/Aims: The serum- and glucocorticoid-inducible kinase SGK1 participates in the orchestration of cardiac hypertrophy and remodeling. Signaling linking SGK1 activity to cardiac remodeling is, however, incompletely understood. SGK1 phosphoryla
Externí odkaz:
https://doaj.org/article/94a5ff984c8e48c0a919ae037013231b
Autor:
Ioana Alesutan, Katharina Musculus, Tatsiana Castor, Kousi Alzoubi, Jakob Voelkl, Florian Lang
Publikováno v:
Kidney & Blood Pressure Research, Vol 40, Iss 5, Pp 490-499 (2015)
Background/Aims: Excessive phosphate concentrations trigger vascular calcification, an active process promoted by osteoinduction of vascular smooth muscle cells (VSMCs) with increased expression and activity of transcription factor RUNX2 (Core-bindin
Externí odkaz:
https://doaj.org/article/16ddce98083f4308a5b5adbcdf7369d4