Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Tatjana Sjakste"'
Autor:
Tatjana Sjakste, Elina Leonova, Rudolfs Petrovs, Ilva Trapina, Marion S. Röder, Nikolajs Sjakste
Publikováno v:
PeerJ, Vol 8, p e8569 (2020)
Background The concept of chromatin domains attached to the nuclear matrix is being revisited, with nucleus described as a set of topologically associating domains. The significance of the tightly bound to DNA proteins (TBP), a protein group that rem
Externí odkaz:
https://doaj.org/article/11260d4bd3f148bdb3aa8e19b93a8c56
Autor:
Natalia Paramonova, Ilva Trapina, Kristine Dokane, Jolanta Kalnina, Tatjana Sjakste, Nikolajs Sjakste
Publikováno v:
Medicina, Vol 56, Iss 4, p 154 (2020)
Background and objectives: Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, leading to demyelination of neurons and potentially debilitating physical and mental symptoms. The disease is more prevalent in women
Externí odkaz:
https://doaj.org/article/06b3b972005547ab88a1d7656df7444e
Autor:
Tatjana Sjakste, Natalia Paramonova, Ingrida Rumba-Rozenfelde, Ilva Trapina, Olga Sugoka, Nikolajs Sjakste
Publikováno v:
Pediatrics and Neonatology, Vol 55, Iss 5, Pp 393-403 (2014)
The ubiquitin proteasome system plays an exceptional biological role in the antigen processing and immune response and it could potentially be involved in pathogenesis of many immunity-related diseases, including juvenile idiopathic arthritis (JIA).
Externí odkaz:
https://doaj.org/article/14c5a2f211524c0783bb069315bcfcce
Autor:
Lawrence Shi-Shin Wu, Tatjana Sjakste, Raimundas Sakalauskas, Brigita Sitkauskiene, Natalia Paramonova, Edita Gasiuniene, Ren-Long Jan, Jiu-Yao Wang
Publikováno v:
Pediatrics and Neonatology, Vol 53, Iss 5, Pp 276-282 (2012)
Asthma is one of the most common chronic respiratory diseases with an increasing prevalence and financial burden worldwide. This disease affects individuals in all countries and all ethnic groups; however, prevalence rates of asthma have been reporte
Externí odkaz:
https://doaj.org/article/845db1cdbc4c4f35835709f974499c03
Autor:
Sarmite Kupca, Tatjana Sjakste, Natalija Paramonova, Olga Sugoka, Irena Rinkuza, Ilva Trapina, Ilva Daugule, Alfred J. Sipols, Ingrida Rumba-Rozenfelde
Publikováno v:
Journal of Obesity, Vol 2013 (2013)
The aim of this study was to ascertain possible associations between childhood obesity, its anthropometric and clinical parameters, and three loci of proteasomal genes rs2277460 (PSMA6 c.-110C>A), rs1048990 (PSMA6 c.-8C>G), and rs2348071 (PSMA3 c. 54
Externí odkaz:
https://doaj.org/article/aba7d1e1b14645b69fff7ea0d2b3f191
Autor:
Kristine Dislere, Ilva Trapina, Tatjana Sjakste, Jolanta Kalnina, Kristine Dokane, Nikolajs Sjakste, Natalia Paramonova
Publikováno v:
Experimental and Therapeutic Medicine. 21
Several polymorphisms in genes related to the ubiquitin-proteasome system exhibit an association with pathogenesis and prognosis of various human autoimmune diseases. Our previous study reported the association between multiple sclerosis (MS) and the
Autor:
Natalia, Paramonova, Jolanta, Kalnina, Kristine, Dokane, Kristine, Dislere, Ilva, Trapina, Tatjana, Sjakste, Nikolajs, Sjakste
Publikováno v:
Experimental and Therapeutic Medicine
Several polymorphisms in genes related to the ubiquitin-proteasome system exhibit an association with pathogenesis and prognosis of various human autoimmune diseases. Our previous study reported the association between multiple sclerosis (MS) and the
Autor:
Tatjana Sjakste, Elina Leonova, Gunars Duburs, Larisa Baumane, Egils Bisenieks, Sergejs Isajevs, Nikolajs Sjakste, Brigita Vīgante, Evita Rostoka, Kristīne Ošiņa
Publikováno v:
Archives of Industrial Hygiene and Toxicology. 68:212-227
Studies on the pathogenesis of diabetes mellitus complications indicate that the compounds reducing free radicals and enhancing DNA repair could be prospective as possible remedies. Carbatonides, the disodium-2,6-dimethyl-1,4- dihydropyridine-3,5-bis
Autor:
Lubov Ignatovich, Calvin Yu-Chian Chen, Nikolajs Sjakste, Tatjana Sjakste, Elina Leonova, Mara Grube, Karlis Shvirksts
Publikováno v:
Toxicological & Environmental Chemistry. 99:601-612
Ftorafur is an antimetabolite antitumour drug successfully used for treatment of various tumours. It is generally accepted that ftorafur is converted to 5-fluoruracil. However, some data indicate direct interactions of the compound with DNA. To test
Publikováno v:
Biopolymers and Cell, Vol 32, Iss 3, Pp 184-189 (2016)
The ryanodine receptor 1 (RYR1) is a calcium ion channel in the sarcoplasmic reticulum of skeletal muscle. Multiple polymorphic loci have been identified in the RYR1 gene in human and animals and some of them are associated with certain phenotypes. H