The haloarchaeal MCM proteins: bioinformatic analysis and targeted mutagenesis of the β7-β8 and β9-β10 hairpin loops and conserved zinc binding domain cysteines

Autor: Stuart A. MacNeill, Tatjana P Kristensen, Reeja Maria Cherian, Fiona C. Gray

Publikováno v: Frontiers in Microbiology, Vol 5 (2014)
Frontiers in Microbiology
Kristensen, T P, Cherian, R M, Gray, F C & Macneill, S A 2014, ' The haloarchaeal MCM proteins : bioinformatic analysis and targeted mutagenesis of the β7-β8 and β9-β10 hairpin loops and conserved zinc binding domain cysteines ', Frontiers in Microbiology, vol. 5, 123 . https://doi.org/10.3389/fmicb.2014.00123

The hexameric MCM complex is the catalytic core of the replicative helicase in eukaryotic and archaeal cells. Here we describe the first in vivo analysis of archaeal MCM protein structure and function relationships using the genetically tractable hal

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http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00123/full