Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Tatjana Keesen, de Souza Lima"'
1
Immune hallmarks of rheumatoid arthritis management: A brief review
Autor: Rephany Fonseca Peixoto, Carlos Ewerton Maia Rodrigues, Pedro Henrique de Sousa Palmeira, Fernando Cézar Comberlang Queiroz Davis dos Santos, Tatjana Keesen de Souza Lima, Alessandra de Sousa Braz
Publikováno v: Cytokine. 158
The purpose of this review was to examine current evidence on immunomodulation mediated by conventional drugs and the use of novel biological agents for the treatment of rheumatoid arthritis (RA). Currently, treatment is focused on maximizing quality
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8fdd28a118e3c1c9c8aef94971ed0a
https://pubmed.ncbi.nlm.nih.gov/35985174
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2
Antiproliferative, antileishmanial and antimicrobial studies on Cnidoscolus quercifolius Pohl (Euphorbiaceae)
Autor: Harley da Silva Alves, Antônio Carlos Santos Rocha Júnior, Geovana Ferreira Guedes Silvestre, Tatjana Keesen de Souza Lima, Ana Lúcia Tasca Gois Ruiz, Anna Flávia Costa Fernandes
Publikováno v: Natural Product Research. 35:5339-5343
Cnidoscolus quercifolius is an Euphorbiaceae endemic to the northeast region of Brazil, which is used in folk medicine as anti-inflammatory, analgesic and antibiotic. An ethanolic extract was prepared with the leaves from C. quercifolius, and also pa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa621cc7bad10c80760c59d0fafded48
https://doi.org/10.1080/14786419.2020.1758089
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3
Design, Antileishmanial Activity, and QSAR Studies of a Series of Piplartine Analogues
Autor: Damião Pergentino de Sousa, Carlos da Silva Maia Bezerra Filho, Yunierkis P. Castillo, Daniel P. Bezerra, Tamires Cardoso Lima, Flávio Rogério da Nóbrega, Larisse Virgolino da Silva, Tatjana Keesen de Souza Lima
Publikováno v: Journal of Chemistry, Vol 2019 (2019)
Piplartine is an alkamide found in different Piper species and possesses several biological activities, including antiparasitic properties. Thus, the aim of the present study was to evaluate a series of 32 synthetic piplartine analogues against the L
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200a6886cb57589f6013a3e5a942c2a6
https://doi.org/10.1155/2019/4785756
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6
Akademický článek
Toll receptors type-2 and CR3 expression of canine monocytes and its correlation with immunohistochemistry and xenodiagnosis in visceral leishmaniasis.
Autor: Izabela Ferreira Gontijo de Amorim, Sydnei Magno da Silva, Maria Marta Figueiredo, Eliane Perlatto Moura, Rodrigo Soares de Castro, Tatjana Keesen de Souza Lima, Nelder de Figueiredo Gontijo, Marilene Suzan Marques Michalick, Kenneth John Gollob, Wagner Luiz Tafuri
Publikováno v: PLoS ONE, Vol 6, Iss 11, p e27679 (2011)
The aim of the present study was to investigate TLR2 expression in peripheral blood monocytes from dogs naturally infected with Leishmania (Leishmania) infantum to determine whether it correlates with CD11b/CD18 (CR3) expression, and to evaluate the
Externí odkaz: https://doaj.org/article/9e3749d1e0c8499290ac4b9a23be6b5c
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8
Synthesis of New Cyclic Imides Derived from Safrole, Structure- and Ligand-based Approaches to Evaluate Potential New Multitarget Agents Against Species of Leishmania
Autor: Tatjana Keesen de Souza Lima, Juliana da Câmara Rocha, Normando Alexandre da Silva Costa, Petrônio Filgueiras de Athayde-Filho, Marcus Tullius Scotti, Bruno Freitas Lira, Cristiane Cosmo Silva Luis, Luciana Scotti, José Alixandre de Sousa Luis
Publikováno v: Medicinal chemistry (Shariqah (United Arab Emirates)). 16(1)
Background: Leishmaniasis is a neglected disease that does not have adequate treatment. It affects around 12 million people around the world and is classified as a neglected disease by the World Health Organization. In this context, strategies to obt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50fe6d770aa388ffef74c9f1bdecb225
https://pubmed.ncbi.nlm.nih.gov/31208311
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9
Structure- and Ligand-Based Approaches to Evaluate Aporphynic Alkaloids from Annonaceae as Multi-Target Agent Against Leishmania donovani
Autor: Luciana Scotti, Tatjana Keesen de Souza Lima, Ana Silvia Suassuna Carneiro Lúcio, Marcus Tullius Scotti, Juliana da Câmara Rocha, José Maria Barbosa Filho, Josean Fechine Tavares, Vitor Prates Lorenzo
Publikováno v: Current pharmaceutical design. 22(34)
Background: Leishmaniasis is a neglected disease that affects 15 million people around the world. Many limitations are associated to the treatment as high cost and toxicity. Several classes of natural substances with proven leishmanicidal activity we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf98d25952f6f13b668e708d3f3754f
https://pubmed.ncbi.nlm.nih.gov/27174814
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10
Violacein induces cell death by triggering mitochondrial membrane hyperpolarization in vitro
Autor: Angélica Maria de Sousa Leal, Tatjana Keesen de Souza Lima, Jana Dara Freires de Queiroz, Lucymara Fassarella Agnez-Lima, Silvia Regina Batistuzzo de Medeiros
Publikováno v: BMC Microbiology
Background Violacein is a purple pigment from Chromobacterium violaceum that possesses diverse biological and pharmacological properties. Among these, pro-oxidant and antioxidant activities have been suggested. However, the cytotoxic mechanisms induc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e59d119c22176d85915a1c348cb0209
http://europepmc.org/articles/PMC4457087
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