Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Tatjana ALBREKTSEN"'
Autor:
Brit B. Sørensen, Usha R. Pendurthi, Gertrud M. Hjortoe, Lars Christian Petersen, Samir K. Mandal, Peder Lisby Nørby, Tatjana Albrektsen, L. Vijaya Mohan Rao
Publikováno v:
Blood. 103:3029-3037
Tissue factor (TF), the cellular receptor for factor VIIa (FVIIa), besides initiating blood coagulation, is believed to play an important role in tissue repair, inflammation, angiogenesis, and tumor metastasis. Like TF, the chemokine interleukin-8 (I
Autor:
L. Anders Svensson, Per Sauerberg, Klaus Stensgaard Frederiksen, Jan Fleckner, Ingrid Pettersson, Steen B. Mortensen, Karsten Wassermann, Lars Ynddal, Lone Jeppesen, Tatjana Albrektsen, Jan Nehlin, Paul Stanley Bury, Erik M. Wulff, John Patrick Mogensen, Nanni Din
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:257-260
Using a known dual PPARα/γ activator (5) as a structural template, SAR evaluations led to the identification of triple PPARα/γ/δ activators (18–20) with equal potency and efficacy on all three receptors. These compounds could become useful too
Autor:
Susanne Mandrup, Leif K. Larsen, Maria Sandberg Boysen, Jane Nøhr, Søren Sindberg Jensen, Tatjana Albrektsen, Pia Kiilerich, Karsten Kristiansen, Luc E. G. Rietveld, Lars Grøntved, Jan Fleckner, Hendrik G. Stunnenberg, Torben Helledie
Publikováno v:
Journal of Biological Chemistry, 277, 26821-26830
Journal of Biological Chemistry, 277, 30, pp. 26821-26830
Helledie, T, Grøntved, L, Jensen, S S, Kiilerich, P, Rietveld, L, Albrektsen, T, Boysen, M S, Nøhr, J, Larsen, L K, Fleckner, J, Stunnenberg, H G, Kristiansen, K & Mandrup, S 2002, ' The gene encoding the Acyl-CoA-binding protein is activated by peroxisome proliferator-activated receptor gamma through an intronic response element functionally conserved between humans and rodents. ', Journal of Biological Chemistry, vol. 277, no. 30, pp. 26821-30 . https://doi.org/10.1074/jbc.M111295200
Journal of Biological Chemistry, 277, 30, pp. 26821-26830
Helledie, T, Grøntved, L, Jensen, S S, Kiilerich, P, Rietveld, L, Albrektsen, T, Boysen, M S, Nøhr, J, Larsen, L K, Fleckner, J, Stunnenberg, H G, Kristiansen, K & Mandrup, S 2002, ' The gene encoding the Acyl-CoA-binding protein is activated by peroxisome proliferator-activated receptor gamma through an intronic response element functionally conserved between humans and rodents. ', Journal of Biological Chemistry, vol. 277, no. 30, pp. 26821-30 . https://doi.org/10.1074/jbc.M111295200
Udgivelsesdato: 2002-Jul-26 The acyl-CoA-binding protein (ACBP) is a 10-kDa intracellular protein that specifically binds acyl-CoA esters with high affinity and is structurally and functionally conserved from yeast to mammals. In vitro studies indica
Publikováno v:
Biochemical Journal. 359:393-402
Adipocyte differentiation is co-ordinately regulated by several transcription factors and is accompanied by changes in the expression of a variety of genes. Using mRNA differential display analysis, we have isolated a novel mRNA, DD16, specifically i
Autor:
Jan Fleckner, Tatjana Albrektsen
Publikováno v:
Molecular Pharmacology. 59:567-575
Thiazolidinediones (TZDs) are a new class of compounds that improve the insulin sensitivity in patients with non-insulin-dependent diabetes mellitus (NIDDM) as well as in rodent models of NIDDM. These compounds act as high-affinity ligands for a memb
Publikováno v:
Current Pharmaceutical Biotechnology. 1:63-71
The discovery of the important metabolic and physiological role played by a family of transcription factors, the peroxisome proliferator activated receptors (PPAR), has opened up for a new understanding of the mode of action for the lipid lowering dr
Autor:
Stefan Rehnmark, Nobuteru Usuda, Dorothee Feltkamp, Hebe M. Guardiola-Diaz, Stefan E.H. Alexson, Jan-Åke Gustafsson, Tatjana Albrektsen
Publikováno v:
Journal of Biological Chemistry. 274:23368-23377
Brown adipose tissue (BAT) hyperplasia is a fundamental physiological response to cold; it involves an acute phase of mitotic cell growth followed by a prolonged differentiation phase. Peroxisome proliferator-activated receptors (PPARs) are key regul
Autor:
Brit B. Sørensen, Tatjana Albrektsen, Gertrud M. Hjortø, Lars Christian Petersen, Marianne Kjalke, Søren E. Bjørn
Publikováno v:
Thrombosis and Haemostasis. 98:909-911
Factor VIIa/tissue factor-dependent gene regulation and pro-coagulant activity: Effect of factor VIIa concentration
Publikováno v:
Molecular Endocrinology. 12:864-881
Transcriptional regulation of gene expression by nuclear receptors requires negatively and positively acting cofactors. Recent models for receptor activation propose that certain receptors in the absence of ligands can recruit corepressors while liga
Autor:
Lars C, Petersen, Tatjana, Albrektsen, Gertrud M, Hjortø, Marianne, Kjalke, Søren E, Bjørn, Brit B, Sørensen
Publikováno v:
Thrombosis and haemostasis. 98(4)