Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Tatjana, Williams"'
Autor:
Monique Jänsch, Lubomir T. Lubomirov, Maximilian Trum, Tatjana Williams, Joachim Schmitt, Kai Schuh, Fatimunnisa Qadri, Lars S. Maier, Michael Bader, Oliver Ritter
Publikováno v:
FEBS Open Bio, Vol 13, Iss 1, Pp 118-132 (2023)
Recent evidence demonstrated that alterations in the QT interval duration on the ECG are not only determined by mutations in genes for ion channels, but also by modulators of ion channels. Changes in the QT interval duration beyond certain thresholds
Externí odkaz:
https://doaj.org/article/8069512204c84c57aff6a458cf969748
Autor:
Maria Shoykhet, Orsela Dervishi, Philipp Menauer, Matthias Hiermaier, Sina Moztarzadeh, Colin Osterloh, Ralf J. Ludwig, Tatjana Williams, Brenda Gerull, Stefan Kääb, Sebastian Clauss, Dominik Schüttler, Jens Waschke, Sunil Yeruva
Publikováno v:
JCI Insight, Vol 8, Iss 6 (2023)
Arrhythmogenic cardiomyopathy (AC) is a familial heart disease partly caused by impaired desmosome turnover. Thus, stabilization of desmosome integrity may provide new treatment options. Desmosomes, apart from cellular cohesion, provide the structura
Externí odkaz:
https://doaj.org/article/2beededbb67b40438a622d5e5d48e306
Autor:
Miriam Zink, Anne Seewald, Mareike Rohrbach, Andreas Brodehl, Daniel Liedtke, Tatjana Williams, Sarah J. Childs, Brenda Gerull
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9530 (2022)
Arrhythmogenic cardiomyopathy (ACM) is an inherited heart muscle disease caused by heterozygous missense mutations within the gene encoding for the nuclear envelope protein transmembrane protein 43 (TMEM43). The disease is characterized by myocyte lo
Externí odkaz:
https://doaj.org/article/35d6def1145d4b15abc89c047ae62d2e
Autor:
Maria Shoykhet, Sebastian Trenz, Ellen Kempf, Tatjana Williams, Brenda Gerull, Camilla Schinner, Sunil Yeruva, Jens Waschke
Publikováno v:
JCI Insight, Vol 5, Iss 18 (2020)
Arrhythmogenic cardiomyopathy (AC) is a heart disease often caused by mutations in genes coding for desmosomal proteins, including desmoglein-2 (DSG2), plakoglobin (PG), and desmoplakin (DP). Therapy is based on symptoms and limiting arrhythmia, beca
Externí odkaz:
https://doaj.org/article/046bc78228534ea894a7626e9670aea9
Autor:
Moritz Hundertmark, Tatjana Williams, Anja Vogel, Maria Moritz, Peter Bramlage, Nikolaos Pagonas, Oliver Ritter, Benjamin Sasko
Publikováno v:
Case Reports in Infectious Diseases, Vol 2019 (2019)
A rare consequence of dog bites is the infection with Capnocytophaga canimorsus, and only a few cases have been documented. We describe a 41-year-old, formerly healthy woman who died from septic shock and multiorgan failure. It is the first case of a
Externí odkaz:
https://doaj.org/article/2d1d41016efe4eabbd8aa7bdbba32ac9
Autor:
Ruping Chen, Simone Buchmann, Amos Kroth, Anahi-Paula Arias-Loza, Michael Kohlhaas, Nicole Wagner, Gianna Grüner, Alexander Nickel, Alexandra Cirnu, Tatjana Williams, Christoph Maack, Süleyman Ergün, Stefan Frantz, Brenda Gerull
Publikováno v:
Circulation Research. 132
Background: Nuclear envelope proteins play an important role in the pathogenesis of hereditary cardiomyopathies. Recently, a new form of arrhythmic cardiomyopathy caused by a homozygous mutation (p.L13R) in the inner nuclear membrane protein LEMD2 wa
Autor:
Monique Jänsch, Lubomir T. Lubomirov, Maximilian Trum, Tatjana Williams, Joachim Schmitt, Kai Schuh, Fatimunnisa Qadri, Lars S. Maier, Michael Bader, Oliver Ritter
Publikováno v:
FEBS open bioReferences.
Recent evidence demonstrated that alterations in the QT interval duration on the ECG are not only determined by mutations in genes for ion channels, but also by modulators of ion channels. Changes in the QT interval duration beyond certain thresholds
Autor:
Miriam, Zink, Anne, Seewald, Mareike, Rohrbach, Andreas, Brodehl, Daniel, Liedtke, Tatjana, Williams, Sarah J, Childs, Brenda, Gerull
Publikováno v:
International journal of molecular sciences. 23(17)
Arrhythmogenic cardiomyopathy (ACM) is an inherited heart muscle disease caused by heterozygous missense mutations within the gene encoding for the nuclear envelope protein transmembrane protein 43 (
Autor:
Maximilian Trum, F Qadri, Lars S. Maier, M Bader, Oliver Ritter, M Jaensch, Tatjana Williams, Kai Schuh, Joachim P. Schmitt
Publikováno v:
European Heart Journal. 42
Background 35.3% of deaths in 2019 in Germany are caused by cardiovascular diseases (Destatis). 95% of these people were 60 years and older. To increase survival rate in elderly patients we investigate the relevance of altered expression of neuronal
Mutations in ILK, encoding integrin-linked kinase, are associated with arrhythmogenic cardiomyopathy
Autor:
Tatjana Williams, Daniel Liedtke, Henry J. Duff, Nicole M. Munsie, Jan M. Friedman, Saman Rezazadeh, William T. Gibson, Brenda Gerull, Raechel A. Ferrier, Steven J.M. Jones, Yaoqing Shen, Amy L. Stiegler, Titus J. Boggon, Andreas Brodehl, Tracey Oh, Sarah J. Childs
Publikováno v:
Transl Res
Arrhythmogenic cardiomyopathy is a genetic heart muscle disorder characterized by fibro-fatty replacement of cardiomyocytes leading to life-threatening ventricular arrhythmias, heart failure and sudden cardiac death. Mutations in genes encoding cardi