Antifungal activity of naphthoquinoidal compounds in vitro against fluconazole-resistant strains of different Candida species: a special emphasis on mechanisms of action on Candida tropicalis.

Autor: João B A Neto, Cecília R da Silva, Maria A S Neta, Rosana S Campos, Janaína T Siebra, Rose A C Silva, Danielle M Gaspar, Hemerson I F Magalhães, Manoel O de Moraes, Marina D P Lobo, Thalles B Grangeiro, Tatiane S C Carvalho, Emilay B T Diogo, Eufrânio N da Silva Júnior, Felipe A R Rodrigues, Bruno C Cavalcanti, Hélio V N Júnior

Publikováno v: PLoS ONE, Vol 9, Iss 5, p e93698 (2014)

In recent decades, the incidence of candidemia in tertiary hospitals worldwide has substantially increased. These infections are a major cause of morbidity and mortality; in addition, they prolong hospital stays and raise the costs associated with tr

Externí odkaz: https://doaj.org/article/31386306c94d459888cc87fb24b0f1df

Naphthoquinone Derivatives as Scaffold to Develop New Drugs for Tuberculosis Treatment

Autor: Tatiane S. C. Carvalho, Priscila Cristina Bartolomeu Halicki, Pedro Eduardo Almeida da Silva, Maria do Carmo F. R. Pinto, Laís A. Ferreira, Paula F. Carneiro, Kelly C. G. de Moura, Daniela Fernandes Ramos, Karina Pena Del Rio

Publikováno v: Frontiers in Microbiology, Vol 9 (2018)
Frontiers in Microbiology

Despite being a curable disease, tuberculosis (TB) remains a public health problem worldwide mainly due to lengthy treatment, as well as its toxic effects, TB/HIV co-infection and the emergence of resistant Mycobacterium tuberculosis strains. These b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e78139a6ad074ef18271ffb6e3152ffc
http://journal.frontiersin.org/article/10.3389/fmicb.2018.00673/full

Antifungal Activity of Naphthoquinoidal Compounds In Vitro against Fluconazole-Resistant Strains of Different Candida Species: A Special Emphasis on Mechanisms of Action on Candida tropicalis

Autor: Hemerson Iury Ferreira Magalhães, Emilay B. T. Diogo, Tatiane S. C. Carvalho, Marina Duarte Pinto Lobo, Rosana de Sousa Campos, Hélio Vitoriano Nobre Júnior, João Batista de Andrade Neto, Thalles B. Grangeiro, Bruno C. Cavalcanti, Rose Anny Costa Silva, Felipe A. R. Rodrigues, Danielle Macedo Gaspar, Manoel Odorico de Moraes, Janaína T. Siebra, Cecília Rocha da Silva, Maria A. S. Neta, Eufrânio N. da Silva Júnior

Publikováno v: PLoS ONE, Vol 9, Iss 5, p e93698 (2014)
Repositório Institucional da Universidade Federal do Ceará (UFC)
Universidade Federal do Ceará (UFC)
instacron:UFC
PLoS ONE

In recent decades, the incidence of candidemia in tertiary hospitals worldwide has substantially increased. These infections are a major cause of morbidity and mortality; in addition, they prolong hospital stays and raise the costs associated with tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1abbd2f6ee28c63e5c05b762b643b1f
https://doi.org/10.1371/journal.pone.0093698