Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Tatiane Freitas, Borgati"'
Autor:
Tatiane Freitas Borgati, Maria Fernanda Alves do Nascimento, Juma Fortunato Bernardino, Lunamaura Claudia Oliveira Martins, Alex Gutterres Taranto, Alaíde Braga de Oliveira
Publikováno v:
Journal of Tropical Medicine, Vol 2017 (2017)
A total of 28 lapachol-related naphthoquinones with four different scaffolds were synthesized and spectroscopically characterized. In vitro antiplasmodial activity was assayed against the chloroquine-resistant Plasmodium falciparum W2 strain by the p
Externí odkaz:
https://doaj.org/article/e483b30961e94aa49b5b7a4b4e7faa53
Autor:
Ricardo Toshio Fujiwara, Raquel Martins de Almeida, Tatiane Freitas Borgati, Almodvar Baldaia, Sebastião Rodrigo Ferreira, Isabel V. Antolínez, Luiz C. A. Barbosa
Publikováno v:
Chemistrybiodiversity. 17(6)
Leishmaniasis is a neglected disease, caused by a parasite of Leishmania genus and widespread in the tropical and subtropical areas of the world. Currents drugs are limited due to their toxicity and parasite resistance. Therefore, the discovery of ne
Autor:
Tatiane Freitas Borgati, Guilherme Rocha Pereira, Geraldo Célio Brandão, Alaíde Braga de Oliveira, José Dias Souza Filho
Publikováno v:
Orbital: The Electronic Journal of Chemistry, Vol 4, Iss 1, Pp 21-22 (2012)
The goal of this project is synthesize and characterization of derivatives of lupeol and evaluated antimalarial activity. Historically, plants are important source of antimalarial medicines, highlighting quinine (1) (Figure 1), an important alkaloid
Externí odkaz:
https://doaj.org/article/87a51c73f155453297ccddd216fa098a
Autor:
Douglas Costa Gontijo, Nivaldo L. Speziali, José Dias de Souza Filho, Maria Fernanda Alves do Nascimento, Tatiane Freitas Borgati, Alaíde Braga de Oliveira
Publikováno v:
Chemistry & Biodiversity. 16
Bioguided fractionation of Xylopia sericea antiplasmodial dichloromethane leaves extract led to the isolation of (-)-7-oxo-ent-kaur-16-en-19-oic acid (C20 H28 O3 ) that was identified by a combination of 1D and 2D NMR experiments (COSY, HMBC, HSQC, H
Publikováno v:
Journal of the Brazilian Chemical Society v.30 n.6 2019
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 30, Issue: 6, Pages: 1138-1149, Published: 23 MAY 2019
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 30, Issue: 6, Pages: 1138-1149, Published: 23 MAY 2019
A complete and unambiguous assignment of 1H and 13C nuclear magnetic resonance (NMR) signals of 29 naphthoquinones is reported on the basis of one- and two-dimensional NMR techniques (1H, 13C, 1H-1H correlated spectroscopy (COSY) and 1H-13C heteronuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d57d84d49166989417a0380afc0fc7e
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532019000601138
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532019000601138
Autor:
Douglas, Costa Gontijo, Maria, Fernanda Alves do Nascimento, Tatiane Freitas, Borgati, Nivaldo Lúcio, Speziali, José, Dias de Souza Filho, Alaíde, Braga de Oliveira
Publikováno v:
Chemistrybiodiversity. 16(7)
Bioguided fractionation of Xylopia sericea antiplasmodial dichloromethane leaves extract led to the isolation of (-)-7-oxo-ent-kaur-16-en-19-oic acid (C
Autor:
Tatiane Freitas Borgati, Alaíde Braga de Oliveira, Carlos Alberto Tagliati, Larissa Camila Ribeiro de Souza, Maria Fernanda Alves do Nascimento
Publikováno v:
Toxicology and Applied Pharmacology. 401:115074
The natural naphthoquinones lapachol, α- and β-lapachone are found in Bignoniaceous Brazilian plant species of the Tabebuia genus (synonym Handroanthus) and are recognized for diverse bioactivities, including as antimalarial. The aim of the present
Autor:
Alex Gutterres Taranto, Alaíde Braga de Oliveira, Tatiane Freitas Borgati, Maria Fernanda Alves do Nascimento, Lunamaura Claudia Oliveira Martins, Juma Fortunato Bernardino
Publikováno v:
Journal of Tropical Medicine, Vol 2017 (2017)
Journal of Tropical Medicine
Journal of Tropical Medicine
A total of 28 lapachol-related naphthoquinones with four different scaffolds were synthesized and spectroscopically characterized. In vitro antiplasmodial activity was assayed against the chloroquine-resistant Plasmodium falciparum W2 strain by the p
Autor:
Alaíde Braga de Oliveira, Renata Cristina de Paula, Dayane Aparecida Morais Fernandes, Tatiane Freitas Borgati, Guilherme R. Pereira, Luciana Ferreira Soares, Geraldo Célio Brandão, Júlio César Dias Lopes, Maria Fernanda Alves do Nascimento, Juliana Braga de Oliveira Santos, José Dias de Souza Filho
Publikováno v:
Repositório Institucional da UFOP
Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP
Journal of the Brazilian Chemical Society v.28 n.10 2017
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 28, Issue: 10, Pages: 1850-1856, Published: OCT 2017
Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP
Journal of the Brazilian Chemical Society v.28 n.10 2017
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 28, Issue: 10, Pages: 1850-1856, Published: OCT 2017
Lupeol, a triterpene frequently found in Asteraceae plant species, showed moderate to low activity in different strains of Plasmodium falciparum, the most virulent malaria etiological agents. In this work, lupeol was isolated from Parahancornia fasci
Autor:
Lucas M. Arantes, Maria Fernanda Alves do Nascimento, Alex Gutterres Taranto, Juliana Braga de Oliveira Santos, Luciana Ferreira Soares, Fernando de Pilla Varotti, Alaíde Braga de Oliveira, Guilherme R. Pereira, Márlia Regina C. Ferreira, Renata Cristina de Paula, Tatiane Freitas Borgati, Geraldo Célio Brandão
Publikováno v:
Journal of the Brazilian Chemical Society.
We herein report the synthesis of hybrid kauranoid molecules of type 1,2,3-triazole-1,4-disubstituted aiming to improve the antimalarial activity of kaurenoic and xylopic acids. The CuI-catalyzed cycloaddition of azides and kauranoid terminal alkynes