Environmental Triazole Induces Cross-Resistance to Clinical Drugs and Affects Morphophysiology and Virulence of Cryptococcus gattii and C. neoformans

Autor: Gustavo José Cota de Freitas, Marliete Carvalho Costa, Guilhem Janbon, Lorena Vívien Neves de Oliveira, Frédérique Moyrand, Gabriella Freitas Ferreira, Hellem Cristina Silva Carneiro, Thais Furtado Ferreira Magalhães, Rafael Wesley Bastos, Karen Maia Rocha, Vanessa S. D. Carvalho, Cláudia Emanuela Viana Rocha, Tatiane Alves de Paixão, Daniel Assis Santos

Publikováno v: Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2018, 62 (1), pp.e01179-17. ⟨10.1128/AAC.01179-17⟩
Antimicrobial Agents and Chemotherapy, 2018, 62 (1), pp.e01179-17. ⟨10.1128/AAC.01179-17⟩

Cryptococcus gattii and Cryptococcus neoformans are environmental fungi that cause cryptococcosis, which is usually treated with amphotericin B and fluconazole. However, therapeutic failure is increasing because of the emergence of resistant strains.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae1627f74b4a2223df1d4b4e7592324
https://pubmed.ncbi.nlm.nih.gov/29109169