Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Tatiana Y. Besschetnova"'
Cell autonomous ANTXR1-mediated regulation of extracellular matrix components in primary fibroblasts
Publikováno v:
Matrix Biology. 62:105-114
Our previous studies of Antxr1 knockout mice suggested that fibrotic skin abnormalities in these mice are associated with increased VEGF signaling. Here, based on studies of primary fibroblasts isolated from skin of Antx1+/+ and Antxr1−/− mice at
Publikováno v:
Journal of Orthopaedic Research. 35:1461-1469
BMP2 is widely used for promotion of bone repair and regeneration. However, bone formation induced by BMP2 is quite variable. Bone forming progenitor cells in different locations appear to respond to BMP2 in different ways, and repair outcomes can va
Publikováno v:
International Journal of Experimental Pathology. 97:296-302
Studies of proliferative hemangiomas have led to the discovery that interactions of endothelial cells with extracellular matrix and/or Vascular Endothelial Growth Factor (VEGF)‐A stimulate the expression of VEGFR1, the VEGF decoy receptor, and supp
Autor:
Tatiana Y. Besschetnova, Negin Katebi, Takaharu Ichimura, Joseph V. Bonventre, Bjorn R. Olsen, Brad St. Croix
Publikováno v:
Matrix biology : journal of the International Society for Matrix Biology
It is well known that angiogenesis is linked to fibrotic processes in fibroproliferative diseases, but insights into pathophysiological processes are limited, due to lack of understanding of molecular mechanisms controlling endothelial and fibroblast
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 35(7)
BMP2 is widely used for promotion of bone repair and regeneration. However, bone formation induced by BMP2 is quite variable. Bone forming progenitor cells in different locations appear to respond to BMP2 in different ways, and repair outcomes can va
Autor:
Jing Zhou, Bjorn R. Olsen, Tatiana Y. Besschetnova, Jagesh V. Shah, Elona Kolpakova-Hart, Yinghua Guan
Publikováno v:
Current Biology. 20(2):182-187
SummaryThe primary cilium acts as a transducer of extracellular stimuli into intracellular signaling [1, 2]. Its regulation, particularly with respect to length, has been defined primarily by genetic experiments and human disease states in which mole
Fibrosis is responsible for chronic progressive kidney failure, which is present in a large number of adults in the developed world. It is increasingly appreciated that acute kidney injury (AKI), resulting in aberrant incomplete repair, is a major co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed4958a375a6f6ee673e4389a2ce05d
https://europepmc.org/articles/PMC3928013/
https://europepmc.org/articles/PMC3928013/
Publikováno v:
Methods in Cell Biology ISBN: 9780123813770
The primary cilium is a specialized organelle that projects from the surface of many cell types. Unlike its motile counterpart it cannot beat but does transduce extracellular stimuli into intracellular signals and acts as a specialized subcellular co
Autor:
Anthony L. Shrout, David J. Montefusco, Tatiana Y. Besschetnova, Frances M. Antommattei, Robert M. Weis, Abdalin E. Asinas
All cells possess transmembrane signaling systems that function in the environment of the lipid bilayer. In the Escherichia coli chemotaxis pathway, the binding of attractants to a two-dimensional array of receptors and signaling proteins simultaneou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e5311b41696b131691920d37032f00
https://europepmc.org/articles/PMC2527904/
https://europepmc.org/articles/PMC2527904/
Autor:
Annick Turbe-Doan, Courtney J. Haycraft, Haiyan Qiu, David R. Beier, Rolf W. Stottmann, Allyson L. Chesebro, Pamela V. Tran, Bradley K. Yoder, Bruce J. Herron, Paul Scherz, Tatiana Y. Besschetnova, Jagesh V. Shah
Characterization of previously described intraflagellar transport (IFT) mouse mutants has led to the proposition that normal primary cilia are required for mammalian cells to respond to the sonic hedgehog (SHH) signal. Here we describe an N-ethyl-N-n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ced6d44ddf539c5211ec3973f19a5e7
https://europepmc.org/articles/PMC4817720/
https://europepmc.org/articles/PMC4817720/