Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Tatiana V. Kudryashova"'
Autor:
Tetsuo Toyama, Tatiana V. Kudryashova, Asako Ichihara, Stefania Lenna, Agnieszka Looney, Yuanjun Shen, Lifeng Jiang, Leyla Teos, Theodore Avolio, Derek Lin, Ulas Kaplan, Grace Marden, Vrinda Dambal, Dmitry Goncharov, Horace Delisser, Robert Lafyatis, Francesca Seta, Elena A. Goncharova, Maria Trojanowska
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-20 (2023)
Abstract Pulmonary arterial hypertension (PAH) is a life-threatening condition characterized by a progressive increase in pulmonary vascular resistance leading to right ventricular failure and often death. Here we report that deficiency of transcript
Externí odkaz:
https://doaj.org/article/eaede2ae9a2148b3a1f591eaf455e313
Autor:
Neha Hafeez, Anna Kirillova, Yunshan Yue, Rashmi J. Rao, Neil J. Kelly, Wadih El Khoury, Yassmin Al Aaraj, Yi‐Yin Tai, Adam Handen, Ying Tang, Danli Jiang, Ting Wu, Yingze Zhang, Dennis McNamara, Tatiana V. Kudryashova, Elena A. Goncharova, Dmitry Goncharov, Thomas Bertero, Mehdi Nouraie, Gang Li, Wei Sun, Stephen Y. Chan
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 7 (2023)
Background Pulmonary arterial hypertension (PAH) is a complex, fatal disease where disease severity has been associated with the single nucleotide polymorphism (SNP) rs2856830, located near the human leukocyte antigen DPA1 (HLA‐DPA1) gene. We aimed
Externí odkaz:
https://doaj.org/article/9664f574fd8840f292c4a425b64c4fd2
Autor:
Lifeng Jiang, Dmitry A. Goncharov, Yuanjun Shen, Derek Lin, Baojun Chang, Andressa Pena, Horace DeLisser, Elena A. Goncharova, Tatiana V. Kudryashova
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Hyper-proliferation of pulmonary arterial vascular smooth muscle cells (PAVSMC) is an important pathological component of pulmonary vascular remodeling in pulmonary arterial hypertension (PAH). Lipogenesis is linked to numerous proliferative diseases
Externí odkaz:
https://doaj.org/article/799f9b0d8c38417b80f6504cc3558567
Autor:
Yuanjun Shen, Dmitry A. Goncharov, Theodore Avolio, Arnab Ray, Evelyn Okorie, Horace DeLisser, Ana L. Mora, Rebecca Vanderpool, Tatiana V. Kudryashova, Elena A. Goncharova
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Pulmonary arterial hypertension (PAH) is a progressive fatal disease with no cure. Inhibition of integrin-linked kinase (ILK) reverses experimental pulmonary hypertension (PH) in male mice, but its effect on severe experimental PH in either male or f
Externí odkaz:
https://doaj.org/article/4601f709d4114b24a25bb465d5235762
Autor:
Dina K. Gaynullina, Tatiana V. Kudryashova, Alexander V. Vorotnikov, Rudolf Schubert, Olga S. Tarasova
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 6037 (2021)
Previously, the abundance of p42/44 and p38 MAPK proteins had been shown to be higher in arteries of 1- to 2-week-old compared to 2- to 3-month-old rats. However, the role of MAPKs in vascular tone regulation in early ontogenesis remains largely unex
Externí odkaz:
https://doaj.org/article/0bbc7a80728344ec9e07c66f5397e52e
Autor:
Tatiana V. Kudryashova, Yuanjun Shen, Andressa Pena, Emily Cronin, Evelyn Okorie, Dmitry A. Goncharov, Elena A. Goncharova
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2957 (2018)
Increased growth and proliferation of distal pulmonary artery vascular smooth muscle cells (PAVSMC) is an important pathological component of pulmonary arterial hypertension (PAH). Transforming Growth Factor-β (TGF-β) superfamily plays a critical r
Externí odkaz:
https://doaj.org/article/8853fca8a13c44fbae0ce4a4d4a1a078
Publikováno v:
Circulation research. 131(9)
Publikováno v:
Circulation Research. 132:1486-1488
Autor:
Bryce Piper, Srimathi Bogamuwa, Tanvir Hossain, Daniela Farkas, Lorena Rosas, Adam Green, Geoffrey Newcomb, Nuo Sun, Jeffrey C. Horowitz, Aneel R Bhagwani, Hu Yang, Tatiana V. Kudryashova, Mauricio Rojas, Ana L. Mora, Pearlly Yan, Rama K. Mallampalli, Elena A. Goncharova, David M. Eckmann, Laszlo Farkas
Publikováno v:
bioRxiv
Pulmonary arterial hypertension (PAH) is a devastating and progressive disease with limited treatment options. Endothelial dysfunction plays a central role in development and progression of PAH, yet the underlying mechanisms are incompletely understo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9640edb699bc62966ed67a5744c80d1
https://europepmc.org/articles/PMC9915659/
https://europepmc.org/articles/PMC9915659/
Autor:
Yuanjun Shen, Dmitry A. Goncharov, Andressa Pena, Jeffrey Baust, Andres Chavez Barragan, Arnab Ray, Analise Rode, Timothy N. Bachman, Baojun Chang, Lifeng Jiang, Paul Dieffenbach, Laura E. Fredenburgh, Mauricio Rojas, Horace DeLisser, Ana L. Mora, Tatiana V. Kudryashova, Elena A. Goncharova
Publikováno v:
Science Signaling. 15
Increased proliferation and survival of cells in small pulmonary arteries (PAs) drive pulmonary arterial hypertension (PAH). Because cell growth mediated by the mTOR-containing mTORC1 complex is inhibited by tuberous sclerosis complex 2 (TSC2), we in