Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Tatiana V. Golovkina"'
Autor:
Elena A. Komarova, Roman V. Kondratov, John R. Goldblum, Kaihua Wang, Tatiana V. Golovkina, Andrei V. Gudkov, Konstantin Christov
Publikováno v:
Oncogene. 23:3265-3271
Ionizing radiation (IR) induces p53-dependent apoptosis in radiosensitive tissues, suggesting that p53 is a determinant of radiation syndromes. In fact, p53-deficient mice survive doses of IR that cause lethal hematopoietic syndrome in wild-type anim
Autor:
Pavel G. Komarov, Kaihua Wang, Tatiana V. Golovkina, Nickolay Neznanov, Dmitry V. Kuprash, Vadim I. Krivokrysenko, Andrei V. Gudkov, Elena A. Komarova, Mikhail V. Chernov, Sergei A. Nedospasov, Stanley L. Hazen, Elena Feinstein, Oskar W. Rokhlin, Marie Luise Brennan
Publikováno v:
The FASEB Journal. 19:1030-1032
Chronic inflammation is known to promote cancer, suggesting that negative regulation of inflammation is likely to be tumor suppressive. We found that p53 is a general inhibitor of inflammation that acts as an antagonist of nuclear factor kappaB (NFka