Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Tatiana V. Denisenko"'
Publikováno v:
Discover Oncology, Vol 12, Iss 1, Pp 1-11 (2021)
Abstract In order to maintain a functional mitochondrial network, cells have developed a quality control mechanism, namely mitophagy. This process can be induced through different pathways. The most studied is the so-called PINK1/Parkin pathway, whic
Externí odkaz:
https://doaj.org/article/19c9a79233374fc6bd88c22958758d8b
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Mitochondria in addition to be a main cellular power station, are involved in the regulation of many physiological processes, such as generation of reactive oxygen species, metabolite production and the maintenance of the intracellular Ca2+ homeostas
Externí odkaz:
https://doaj.org/article/14ef586f915d47deb69ea6f748beb04e
Autor:
Vladimir L. Katanaev, Alexey Baldin, Tatiana V. Denisenko, Denis N. Silachev, Anna E. Ivanova, Gennadiy T. Sukhikh, Lee Jia, Lev A. Ashrafyan
Publikováno v:
Trends in Molecular Medicine. 29:468-480
Publikováno v:
Discover Oncology, Vol 12, Iss 1, Pp 1-11 (2021)
Discover. Oncology
Discover. Oncology
In order to maintain a functional mitochondrial network, cells have developed a quality control mechanism, namely mitophagy. This process can be induced through different pathways. The most studied is the so-called PINK1/Parkin pathway, which is asso
Autor:
Tatiana V. Denisenko, Vladimir Gogvadze, Maria A. Yapryntseva, A D Pivnyuk, Boris Zhivotovsky, Anna S. Gorbunova, T A Prikazchikova
Publikováno v:
Biochemistry. Biokhimiia. 85(10)
BNIP3 is a member of Bcl-2 protein family involved in regulation of various forms of cell death. However, its role in these processes remains unclear and varies depending on the type of cancer cells and environmental factors (pH, O2 level, etc.). Her
Publikováno v:
Cell Death and Disease, Vol 9, Iss 2, Pp 1-14 (2018)
Cell Death & Disease
Cell Death & Disease
The most common type of lung cancer is adenocarcinoma (ADC), comprising around 40% of all lung cancer cases. In spite of achievements in understanding the pathogenesis of this disease and the development of new approaches in its treatment, unfortunat
Publikováno v:
Cancers
Cancers, Vol 12, Iss 3390, p 3390 (2020)
Cancers, Vol 12, Iss 3390, p 3390 (2020)
Simple Summary Bcl-2/adenovirus E1B 19kDa interacting protein 3 (BNIP3) is a pro-apoptotic BH3-only protein of the Bcl-2 family. Its function in various biological processes was described. Although potential involvement of BNIP3 in cancer progression
Publikováno v:
Cancers
The tumor suppressor p53 as the "guardian of the genome" plays an essential role in numerous signaling pathways that control the cell cycle, cell death and in maintaining the integrity of the human genome. p53, depending on the intracellular localiza
Autor:
Vitaliy O. Kaminskyy, Pyotr A. Tyurin-Kuzmin, Boris Zhivotovsky, Irina V. Sorokina, Vladimir Gogvadze, Tatiana V. Denisenko, Gabriela Imreh
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Evading cell death is a major driving force for tumor progression that is one of the main problems in current cancer research. Mitotic catastrophe (MC) represents attractive platform compromising tumor resistance to current therapeutic modalities. MC
Autor:
Gabriela Imreh, Irina V. Sorokina, Boris Zhivotovsky, Vladimir Gogvadze, Tatiana V. Denisenko
Publikováno v:
The international journal of biochemistrycell biology. 81
Mitotic catastrophe (MC) is a sequence of events resulting from premature or inappropriate entry of cells into mitosis that can be caused by chemical or physical stresses. There are several observations permitting to define MC as an oncosuppressive m