Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tatiana Svermova"'
Autor:
Mengjia Li, Haocheng Shou, Guillermo Martínez Corrales, Tatiana Svermova, Alessandra Vieira Franco, Nazif Alic
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109962- (2024)
Summary: Transcription factors can reprogram gene expression to promote longevity. Here, we investigate the role of Drosophila Xbp1. Xbp1 is activated by splicing of its primary transcript, Xbp1u, to generate Xbp1s, a key activator of the endoplasmic
Externí odkaz:
https://doaj.org/article/f18ff14b1908400a871d83a7709ddfbe
Autor:
Adam J Dobson, Richard Boulton-McDonald, Lara Houchou, Tatiana Svermova, Ziyu Ren, Jeremie Subrini, Mireya Vazquez-Prada, Mimoza Hoti, Maria Rodriguez-Lopez, Rita Ibrahim, Afroditi Gregoriou, Alexis Gkantiragas, Jürg Bähler, Marina Ezcurra, Nazif Alic
Publikováno v:
PLoS Genetics, Vol 15, Iss 7, p e1008212 (2019)
Ageing populations pose one of the main public health crises of our time. Reprogramming gene expression by altering the activities of sequence-specific transcription factors (TFs) can ameliorate deleterious effects of age. Here we explore how a circu
Externí odkaz:
https://doaj.org/article/d40fec961f234fed9ed5b2f38dc33346
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111459 (2014)
Endothelial dysfunction associated with systemic inflammation can contribute to organ injury/failure following cardiac surgery requiring cardiopulmonary bypass (CPB). Roundabout protein 4 (Robo4), an endothelial-expressed transmembrane receptor and r
Externí odkaz:
https://doaj.org/article/3a531596277b41c78bc612b8314449ca
Autor:
Guillermo Martínez Corrales, Mengjia Li, Tatiana Svermova, Alex Goncalves, Diana Voicu, Adam J. Dobson, Tony D. Southall, Nazif Alic
Publikováno v:
Nat Aging
A transient, homeostatic transcriptional response can result in transcriptional memory, programming subsequent transcriptional outputs. Transcriptional memory has great but unappreciated potential to alter animal ageing as animals encounter a multitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c16d6a9851aabff623283fa66b4d7233
https://europepmc.org/articles/PMC7614430/
https://europepmc.org/articles/PMC7614430/
Publikováno v:
Cardiovascular Diagnosis and Therapy. 8:121-136
Background: Efficacy of drug-eluting balloons (DEB) for treatment of de novo coronary lesions remains controversial. The present systematic review and meta-analysis of randomised controlled trials assessed DEB with bare-metal stents (BMS) and also DE
Autor:
Anne Burke-Gaffney, Tatiana Svermova, Jasarat Chowdhury, John Wort, Zacharoula Nikolakopoulou
Publikováno v:
4.3 Pulmonary Circulation and Pulmonary Vascular Diseases.
Roundabout (Robo) receptors 1 and 4 and their ligand Slit2, are novel regulators of endothelial cell (EC) function. Robo1/4 can have co-operative and/or opposing effects on cell function. Expression levels vary between EC and it is likely that functi