Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Tatiana R. Martins"'
Autor:
Diana Fontinha, Daniel Simão, Beatrice Greco, Sofia P. Rebelo, Claude Oeuvray, Paula M. Alves, Lassina Badolo, Francisca Arez, Catarina Brito, Marta Machado, Miguel Prudêncio, Tatiana R. Martins, Thomas Spangenberg, Manuel J.T. Carrondo, Matthias Rottmann, Christoph Fischli
Publikováno v:
ACS Infectious Diseases. 5:1831-1842
The restricted pipeline of drugs targeting the liver stage of Plasmodium infection reflects the scarcity of cell models that mimic the human hepatic phenotype and drug metabolism, as well as Plasmodium hepatic infection. Using stirred-tank culture sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1b0b4df487514d486ee3166477da673
https://doi.org/10.1021/acsinfecdis.9b00144
https://doi.org/10.1021/acsinfecdis.9b00144
Autor:
Tatiana R. Martins, Catarina Brito, Sofia P. Rebelo, Paula M. Alves, Catarina Pinto, Nuno Lopes
Publikováno v:
Methods in Pharmacology and Toxicology ISBN: 9781071601709
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3fca5a590c7d05326de65c737e54c7e
https://doi.org/10.1007/978-1-0716-0171-6_8
https://doi.org/10.1007/978-1-0716-0171-6_8
Autor:
Francisca, Arez, Sofia P, Rebelo, Diana, Fontinha, Daniel, Simão, Tatiana R, Martins, Marta, Machado, Christoph, Fischli, Claude, Oeuvray, Lassina, Badolo, Manuel J T, Carrondo, Matthias, Rottmann, Thomas, Spangenberg, Catarina, Brito, Beatrice, Greco, Miguel, Prudêncio, Paula M, Alves
Publikováno v:
ACS infectious diseases. 5(11)
The restricted pipeline of drugs targeting the liver stage of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d860d2f27d8ac4f2d5ace93fc8f42657
https://pubmed.ncbi.nlm.nih.gov/31479238
https://pubmed.ncbi.nlm.nih.gov/31479238
Autor:
Sofia P. Rebelo, Nathalie Harrer, Paula M. Alves, Marta Estrada, Catarina Brito, Tatiana R. Martins, Catarina Pinto, Pablo Loza-Alvarez, Wolfgang Sommergruber, Emilio J. Gualda, José Cabeçadas
Publikováno v:
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Universitat Politècnica de Catalunya (UPC)
The tumour microenvironment (TME) shapes disease progression and influences therapeutic response. Most aggressive solid tumours have high levels of myeloid cell infiltration, namely tumour associated macrophages (TAM). Recapitulation of the interacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b94cf22f499117031b139db3f32cd52
http://hdl.handle.net/2117/346424
http://hdl.handle.net/2117/346424
Autor:
Teresa Cunha-Oliveira, Claudia V. Pereira, Rui F. Simões, Filomena S. G. Silva, Tatiana R. Martins, Renata Couto, Teresa L. Serafim, Paulo J. Oliveira, Ana R Coelho, Albert A. Rizvanov, Cláudia M. Deus
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Doxorubicin (DOX) is one of the most widely used anti-neoplastic agents. However, treatment with DOX is associated with cumulative cardiotoxicity inducing progressive cardiomyocyte death. Sirtuin 3 (Sirt3), a mitochondrial deacetylase, regulates the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5f399e26ac0b5dd4f47467284c3185
https://hdl.handle.net/10316/44844
https://hdl.handle.net/10316/44844
Autor:
Thomas Spangenberg, Paula M. Alves, Sofia P. Rebelo, Daniel Simão, Claude Oeuvray, Beatrice Greco, Diana Fontinha, Manuel J.T. Carrondo, Tatiana R. Martins, Miguel Prudêncio, Franscisca Arez, Matthias Rottman, Marta Machado, Christoph Fischli, Catarina Brito
Publikováno v:
BMJ Global Health. 4:A5.2-A5
Major progress has been made in the control of malaria leading to significantly reduce the number of cases and deaths. However, to reach the elimination stage, new tools will be needed, including combination of drugs capable of blocking the spread of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a64b095f90407e132d1cad101be1a4d
https://doi.org/10.1136/bmjgh-2019-edc.11
https://doi.org/10.1136/bmjgh-2019-edc.11
Autor:
Catarina Pinto, Catarina Brito, Tatiana R. Martins, Marta Estrada, Sofia P. Rebelo, Paula M. Alves, Wolfgang Sommergruber, Nathalie Harrer
Publikováno v:
ESMO Open. 3:A333
Introduction Tumour initiation, progression and treatment are influenced by its microenvironment (TME). Chronic inflammation is linked to cancer in diverse pathologies and most aggressive solid tumours, including non-small cell lung carcinoma (NSCLC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a757d3d07020663f209a694b1849039
https://doi.org/10.1136/esmoopen-2018-eacr25.784
https://doi.org/10.1136/esmoopen-2018-eacr25.784
Autor:
Ana F. Branco, Ana C. Moreira, Jon M Holy, Vilma A. Sardão, Susana F. Sampaio, Paulo J. Oliveira, Teresa Cunha-Oliveira, Tatiana R. Martins
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
The cardiotoxicity induced by the anti-cancer doxorubicin involves increased oxidative stress, disruption of calcium homeostasis and activation of cardiomyocyte death. Nevertheless, antioxidants and caspase inhibitors often show little efficacy in pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ed97820e365a23da7c47410f6428ae