Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tatiana R, Simonyan"'
Amino acid residue at the 165th position tunes EYFP chromophore maturation. A structure-based design
Autor:
Nadya V. Pletneva, Eugene G. Maksimov, Elena A. Protasova, Anastasia V. Mamontova, Tatiana R. Simonyan, Rustam H. Ziganshin, Konstantin A. Lukyanov, Liya Muslinkina, Sergei Pletnev, Alexey M. Bogdanov, Vladimir Z. Pletnev
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 2950-2959 (2021)
For the whole GFP family, a few cases, when a single mutation in the chromophore environment strongly inhibits maturation, were described. Here we study EYFP-F165G – a variant of the enhanced yellow fluorescent protein – obtained by a single F165
Externí odkaz:
https://doaj.org/article/4132c07af9ba4fe2948940946344ab2f
Autor:
Irina Y. Filippova, Elena A. Dvoryakova, Nikolay I. Sokolenko, Tatiana R. Simonyan, Valeriia F. Tereshchenkova, Nikita I. Zhiganov, Yakov E. Dunaevsky, Mikhail A. Belozersky, Brenda Oppert, Elena N. Elpidina
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
New substrates with glutamine in the P1-position are introduced for the assay of peptidases from the C1 papain family, with a general formula of Glp-Phe-Gln-X, where Glp is pyroglutamyl and X is pNA (p-nitroanilide) or AMC (4-amino-7-methylcoumaride)
Externí odkaz:
https://doaj.org/article/32bf55c2fb8f49538df9f474f9ff196f
Autor:
Tatiana R. Simonyan, Elena A. Protasova, Anastasia V. Mamontova, Aleksander M. Shakhov, Konstantin A. Lukyanov, Eugene G. Maksimov, Alexey M. Bogdanov
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 12907
The real-time monitoring of the intracellular pH in live cells with high precision represents an important methodological challenge. Although genetically encoded fluorescent indicators can be considered as a probe of choice for such measurements, the
Amino acid residue at the 165th position tunes EYFP chromophore maturation. A structure-based design
Autor:
Vladimir Z. Pletnev, Eugene G. Maksimov, Anastasia V. Mamontova, Elena A. Protasova, Rustam H. Ziganshin, Konstantin A. Lukyanov, Nadya V. Pletneva, Sergei Pletnev, Tatiana R. Simonyan, Liya Muslinkina, Alexey M. Bogdanov
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 2950-2959 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 2950-2959 (2021)
Graphical abstract
For the whole GFP family, a few cases, when a single mutation in the chromophore environment strongly inhibits maturation, were described. Here we study EYFP-F165G – a variant of the enhanced yellow fluorescent protein – o
For the whole GFP family, a few cases, when a single mutation in the chromophore environment strongly inhibits maturation, were described. Here we study EYFP-F165G – a variant of the enhanced yellow fluorescent protein – o
Autor:
Elena A, Dvoryakova, Maria A, Klimova, Tatiana R, Simonyan, Ivan A, Dombrovsky, Marina V, Serebryakova, Valeriia F, Tereshchenkova, Yakov E, Dunaevsky, Mikhail A, Belozersky, Irina Y, Filippova, Elena N, Elpidina
Publikováno v:
International journal of molecular sciences. 23(13)
Wheat gliadins contain a large amount of glutamine- and proline-rich peptides which are not hydrolyzed by human digestive peptidases and can cause autoimmune celiac disease and other forms of gluten intolerance in predisposed people. Peptidases that
Publikováno v:
The 8th International Symposium on Sensor Science.
Monitoring of intracellular pH changes in situ can provide valuable information about cellular metabolism and a deeper understanding of physiological processes. Most traditional fluorescent indicators are only capable of a relative assessment of chan
Autor:
Elena A. Dvoryakova, Yakov E. Dunaevsky, Brenda Oppert, Irina Yu. Filippova, Mikhail A. Belozersky, Valeriia F. Tereshchenkova, Elena N. Elpidina, Nikolay I. Sokolenko, Nikita I. Zhiganov, Tatiana R. Simonyan
Publikováno v:
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 7 (2020)
Frontiers in Molecular Biosciences, Vol 7 (2020)
New substrates with glutamine in the P1-position are introduced for the assay of peptidases from the C1 papain family, with a general formula of Glp-Phe-Gln-X, where Glp is pyroglutamyl and X is pNA (p-nitroanilide) or AMC (4-amino-7-methylcoumaride)