Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Tatiana Pushkarsky"'
Autor:
Jessica K. Schenck, Molly T. Karl, Cheryl Clarkson-Paredes, Ashley Bastin, Tatiana Pushkarsky, Beda Brichacek, Robert H. Miller, Michael I. Bukrinsky
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract HIV-associated neurocognitive disorders (HAND) are a spectrum of cognitive impairments that continue to affect approximately half of all HIV-positive individuals despite effective viral suppression through antiretroviral therapy (ART). White
Externí odkaz:
https://doaj.org/article/a29aa98ca3b74c7cb0b605d575593cfb
Autor:
Christophe Vanpouille, Beda Brichacek, Tatiana Pushkarsky, Larisa Dubrovsky, Wendy Fitzgerald, Nigora Mukhamedova, Sofia Garcia‐Hernandez, Doreen Matthies, Anastas Popratiloff, Dmitri Sviridov, Leonid Margolis, Michael Bukrinsky
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Extracellular vesicles (EVs) serve as pivotal mediators of intercellular communication in both health and disease, delivering biologically active molecules from vesicle‐producing cells to recipient cells. In the context of HIV infection, E
Externí odkaz:
https://doaj.org/article/33ef12fdef4d464c99b5528bf7286933
Autor:
Larisa Dubrovsky, Adam Ward, Soo-Ho Choi, Tatiana Pushkarsky, Beda Brichacek, Christophe Vanpouille, Alexei A. Adzhubei, Nigora Mukhamedova, Dmitri Sviridov, Leonid Margolis, Richard B. Jones, Yury I. Miller, Michael Bukrinsky
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
Externí odkaz:
https://doaj.org/article/2c733b8eadb6438ca67dc277db2f2dfe
Autor:
Larisa Dubrovsky, Adam Ward, Soo-Ho Choi, Tatiana Pushkarsky, Beda Brichacek, Christophe Vanpouille, Alexei A. Adzhubei, Nigora Mukhamedova, Dmitri Sviridov, Leonid Margolis, Richard B. Jones, Yury I. Miller, Michael Bukrinsky
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT Apolipoprotein A-I binding protein (AIBP) is a protein involved in regulation of lipid rafts and cholesterol efflux. AIBP has been suggested to function as a protective factor under several sets of pathological conditions associated with inc
Externí odkaz:
https://doaj.org/article/24158fecd114447eb4e602e7aa4a618f
Autor:
Nigora Mukhamedova, Anh Hoang, Dragana Dragoljevic, Larisa Dubrovsky, Tatiana Pushkarsky, Hann Low, Michael Ditiatkovski, Ying Fu, Ryunosuke Ohkawa, Peter J Meikle, Anelia Horvath, Beda Brichacek, Yury I Miller, Andrew Murphy, Michael Bukrinsky, Dmitri Sviridov
Publikováno v:
PLoS Pathogens, Vol 15, Iss 7, p e1007907 (2019)
HIV infection has a profound effect on "bystander" cells causing metabolic co-morbidities. This may be mediated by exosomes secreted by HIV-infected cells and containing viral factors. Here we show that exosomes containing HIV-1 protein Nef (exNef) a
Externí odkaz:
https://doaj.org/article/e9e4d551c4234d93af6f7c00d4033bd0
Autor:
Hann Low, Anh Hoang, Tatiana Pushkarsky, Larisa Dubrovsky, Elizabeth Dewar, Maria-Silvana Di Yacovo, Nigora Mukhamedova, Lesley Cheng, Catherine Downs, Gary Simon, Maria Saumoy, Andrew F Hill, Michael L Fitzgerald, Paul Nestel, Anthony Dart, Jennifer Hoy, Michael Bukrinsky, Dmitri Sviridov
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215620 (2019)
HIV infection is known to be associated with cardiometabolic abnormalities; here we investigated the progression and causes of these abnormalities. Three groups of participants were recruited: HIV-negative subjects and two groups of treatment-naïve
Externí odkaz:
https://doaj.org/article/8a36007eecad4ae2b822de4fdc5bccc8
Autor:
Sutas Suttiprapa, Gabriel Rinaldi, Isheng J Tsai, Victoria H Mann, Larisa Dubrovsky, Hong-Bin Yan, Nancy Holroyd, Thomas Huckvale, Caroline Durrant, Anna V Protasio, Tatiana Pushkarsky, Sergey Iordanskiy, Matthew Berriman, Michael I Bukrinsky, Paul J Brindley
Publikováno v:
PLoS Pathogens, Vol 12, Iss 10, p e1005931 (2016)
Schistosomiasis is the most important helminthic disease of humanity in terms of morbidity and mortality. Facile manipulation of schistosomes using lentiviruses would enable advances in functional genomics in these and related neglected tropical dise
Externí odkaz:
https://doaj.org/article/1f00e14133d744a8928a8c41a4c3c2a2
Autor:
Huanhuan L. Cui, Angela Grant, Nigora Mukhamedova, Tatiana Pushkarsky, Lucas Jennelle, Larisa Dubrovsky, Katharina Gaus, Michael L. Fitzgerald, Dmitri Sviridov, Michael Bukrinsky
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 4, Pp 696-708 (2012)
HIV infection, through the actions of viral accessory protein Nef, impairs activity of cholesterol transporter ABCA1, inhibiting cholesterol efflux from macrophages and elevating the risk of atherosclerosis. Nef also induces lipid raft formation. In
Externí odkaz:
https://doaj.org/article/e59aa69992e94a1c893ec568bab6cedd
Autor:
Ge Li, Robert T Elder, Larisa Dubrovsky, Dong Liang, Tatiana Pushkarsky, Karen Chiu, Tao Fan, Josephine Sire, Michael Bukrinsky, Richard Y Zhao
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11371 (2010)
HIV-1 Vpr is a virion-associated protein. Its activities link to viral pathogenesis and disease progression of HIV-infected patients. In vitro, Vpr moderately activates HIV-1 replication in proliferating T cells, but it is required for efficient vira
Externí odkaz:
https://doaj.org/article/313e82aa97d542b7932285f675fac46c
Autor:
Zahedi Mujawar, Honor Rose, Matthew P Morrow, Tatiana Pushkarsky, Larisa Dubrovsky, Nigora Mukhamedova, Ying Fu, Anthony Dart, Jan M Orenstein, Yuri V Bobryshev, Michael Bukrinsky, Dmitri Sviridov
Publikováno v:
PLoS Biology, Vol 4, Iss 11, p e365 (2006)
Several steps of HIV-1 replication critically depend on cholesterol. HIV infection is associated with profound changes in lipid and lipoprotein metabolism and an increased risk of coronary artery disease. Whereas numerous studies have investigated th
Externí odkaz:
https://doaj.org/article/0947be31510344d6ba8f0aacccdfd721