Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Tatiana P. Kazubskaya"'
Autor:
Svetlana S. Lukina, Alexey M. Burdennyy, Elena A. Filippova, Irina V. Pronina, Tatiana P. Kazubskaya, Dmitry N. Kushlinsky, Dmitriy O. Utkin, Eleonora A. Braga, Vitaly I. Loginov, Nikolay E. Kushlinskii
Publikováno v:
Alʹmanah Kliničeskoj Mediciny, Vol 50, Iss 1, Pp 21-30 (2022)
Background: Borderline ovarian tumors (BOT) belong to the intermediate type between benign and malignant ovarian neoplasms. Serous borderline tumors share common molecular and genetic characteristics with serous carcinomas. An increase in the methyla
Externí odkaz:
https://doaj.org/article/9fb39d7cafc74d29843f2bdcc62f6a49
Autor:
Irina V. Pronina, Leonid A. Uroshlev, Alexey A. Moskovtsev, Danila M. Zaichenko, Elena A. Filippova, Marina V. Fridman, Alexey M. Burdennyy, Vitaly I. Loginov, Tatiana P. Kazubskaya, Nikolay E. Kushlinskii, Alexey A. Dmitriev, Eleonora A. Braga, Olga I. Brovkina
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 824 (2022)
Ovarian cancer (OC) is one of the most common types of cancer among malignancies of the female reproductive system. This pathology is asymptomatic until advanced stages and has a poor prognosis. Our study aimed to search for lncRNA–miRNA–mRNA com
Externí odkaz:
https://doaj.org/article/e2feb5d664f646bc98c2ddd736ffa30f
Autor:
Vitaly I. Loginov, Irina V. Pronina, Elena A. Filippova, Alexey M. Burdennyy, Svetlana S. Lukina, Tatiana P. Kazubskaya, Leonid A. Uroshlev, Marina V. Fridman, Olga I. Brovkina, Natalya V. Apanovich, Alexander V. Karpukhin, Ivan S. Stilidi, Nikolay E. Kushlinskii, Alexey A. Dmitriev, Eleonora A. Braga
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1300 (2022)
Our work aimed to differentiate 20 aberrantly methylated miRNA genes that participate at different stages of development and metastasis of ovarian carcinoma (OvCa) using methylation-specific qPCR in a representative set of clinical samples: 102 prima
Externí odkaz:
https://doaj.org/article/eb0dfe6fd4544a549de064b8c70fc2a0
Autor:
Valentina D. Yakushina, Larisa V. Lerner, Tatiana P. Kazubskaya, Tatiana T. Kondrat'ieva, Somasundaram - Subramanian, Alexander V. Lavrov
Publikováno v:
Клиническая и экспериментальная тиреоидология, Vol 12, Iss 2, Pp 55-64 (2016)
Thyroid cancer is the most frequent endocrine malignancy. In the most cases thyroid cancer arises from follicular cells. Diagnosis of the cancer is based on the cytological analysis of fine needle aspiration biopsy of thyroid nodes. But the accuracy
Externí odkaz:
https://doaj.org/article/07d718be605241d6ae4ddf4dabbbfc48
Autor:
Artemy D. Beniaminov, Grigory A. Puzanov, George S. Krasnov, Dmitry N. Kaluzhny, Tatiana P. Kazubskaya, Eleonora A. Braga, Anna V. Kudryavtseva, Nataliya V. Melnikova, Alexey A. Dmitriev
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Hypermethylation of promoter CpG islands is generally recognized epigenetic mechanism responsible for gene silencing in cancer. However, molecular details on how this epigenetic mark triggers the process of gene downregulation are still elusive. Here
Externí odkaz:
https://doaj.org/article/305e2e3d2ddc42b2874a8d7ca46d722a
Autor:
Eleonora A. Braga, S S Lukina, D. S. Khodyrev, A. M. Burdennyy, A. V. Karpukhin, Vitaly I. Loginov, I. V. Pronina, E. A. Filippova, Tatiana P. Kazubskaya
Publikováno v:
Bulletin of Experimental Biology and Medicine. 172:67-71
Systemic analysis of the relationship between the levels of methylation of 21 microRNA genes and the parameters of breast cancer progression was performed on a representative sample of 91 paired specimens of breast cancer and histologically normal ti
Autor:
Eleonora A. Braga, A. M. Burdennyy, S S Lukina, I. V. Pronina, Vitaly I. Loginov, Tatiana P. Kazubskaya, N A Ivanova, D. S. Khodyrev, E. A. Filippova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 172:57-62
Changes in the methylation levels of 21 microRNA genes in 91 breast cancer samples in comparison with paired samples of histologically unchanged tissue were studied by quantitative methylation-specific PCR. For 19 microRNA genes, a significant increa
Autor:
Eleonora A. Braga, S S Lukina, E. A. Filippova, I. V. Pronina, Vitaly I. Loginov, Tatiana P. Kazubskaya, A M Burdennyi
Publikováno v:
Bulletin of Experimental Biology and Medicine. 171:764-769
We studied the relationship of the levels of microRNA group expression and methylation with clinical and pathomorphological parameters of breast cancer and its immunohistochemical status. Quantitative methylation specific PCR analysis showed a signif
Autor:
N. E. Kushlinskii, E. A. Filippova, Vitaly I. Loginov, N A Ivanova, M. V. Fridman, Tatiana P. Kazubskaya, Eleonora A. Braga, D. O. Utkin, A. M. Burdennyy, S S Lukina, I. V. Pronina
Publikováno v:
Bulletin of Experimental Biology and Medicine. 171:370-374
The role of methylation in the regulation of genes of long noncoding RNA (lncRNA) is still poorly understood. We revealed new hypermethylated lncRNA genes in ovarian tumors and their effect on metastasis of ovarian cancer. A multiple and significant
Autor:
D A Riabchikov, Vitaly I. Loginov, A. M. Burdennyy, T. M. Zavarykina, S S Lukina, Tatiana P. Kazubskaya, M P Kruglova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 170:350-355
We studied the effect of functionally significant polymorphic markers of the ESR1 gene on the risk of breast cancer, tamoxifen resistance, and survival of patients with this type of cancer. The study included 239 primary breast cancer patients withou