Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Tatiana M. Vinogradova"'
Autor:
Dongmei Yang, Christopher H. Morrell, Alexey E. Lyashkov, Syevda Tagirova Sirenko, Ihor Zahanich, Yael Yaniv, Tatiana M. Vinogradova, Bruce D. Ziman, Victor A. Maltsev, Edward G. Lakatta
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Ca2+ and Vm transitions occurring throughout action potential (AP) cycles in sinoatrial nodal (SAN) cells are cues that (1) not only regulate activation states of molecules operating within criticality (Ca2+ domain) and limit-cycle (Vm domain) mechan
Externí odkaz:
https://doaj.org/article/166b7ee0ea03405081d3abe569ea32e3
Autor:
Syevda Tagirova Sirenko, Ihor Zahanich, Yue Li, Yevgeniya O. Lukyanenko, Alexey E. Lyashkov, Bruce D. Ziman, Kirill V. Tarasov, Antoine Younes, Daniel R. Riordon, Yelena S. Tarasova, Dongmei Yang, Tatiana M. Vinogradova, Victor A. Maltsev, Edward G. Lakatta
Publikováno v:
Cells, Vol 10, Iss 11, p 3106 (2021)
Spontaneous AP (action potential) firing of sinoatrial nodal cells (SANC) is critically dependent on protein kinase A (PKA) and Ca2+/calmodulin-dependent protein kinase II (CaMKII)-dependent protein phosphorylation, which are required for the generat
Externí odkaz:
https://doaj.org/article/d34e3e9a556b4610af29e09b6ffdc8e6
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8414 (2021)
The sinoatrial (SA) node is the physiological pacemaker of the heart, and resting heart rate in humans is a well-known risk factor for cardiovascular disease and mortality. Consequently, the mechanisms of initiating and regulating the normal spontane
Externí odkaz:
https://doaj.org/article/0e777107fc7b41819b8fb83a3bbd148a
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Spontaneous firing of sinoatrial (SA) node cells (SANCs) is regulated by cyclic adenosine monophosphate (cAMP)-mediated, protein kinase A (PKA)-dependent (cAMP/PKA) local subsarcolemmal Ca2+ releases (LCRs) from ryanodine receptors (RyR). The LCRs oc
Externí odkaz:
https://doaj.org/article/ed144771fbcb482d98088b9662d37b6d
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 8, p 2173 (2018)
Spontaneous beating of the heart pacemaker, the sinoatrial node, is generated by sinoatrial node cells (SANC) and caused by gradual change of the membrane potential called diastolic depolarization (DD). Submembrane local Ca2+ releases (LCR) from sarc
Externí odkaz:
https://doaj.org/article/66a283609d7d46069b5e4af6f2528f7a
Publikováno v:
Journal of Pharmacological Sciences, Vol 100, Iss 5, Pp 338-369 (2006)
Abstract.: Sarcoplasmic reticulum (SR) Ca2+ cycling, that is, the Ca2+ clock, entrained by externally delivered action potentials has been a major focus in ventricular myocyte research for the past 5 decades. In contrast, the focus of pacemaker cell
Externí odkaz:
https://doaj.org/article/d776e8b553f74b22ac7b92ce0c4e55f1
Autor:
Yue Li, Antoine Younes, Bruce D. Ziman, Kirill V. Tarasov, Alexey E. Lyashkov, Edward G. Lakatta, Dongmei Yang, Yelena S. Tarasova, Victor A. Maltsev, Tatiana M. Vinogradova, Syevda Tagirova Sirenko, Ihor Zahanich, Yevgeniya O. Lukyanenko, Daniel R. Riordon
Publikováno v:
Cells, Vol 10, Iss 3106, p 3106 (2021)
Cells
Volume 10
Issue 11
Cells
Volume 10
Issue 11
Spontaneous AP (action potential) firing of sinoatrial nodal cells (SANC) is critically dependent on protein kinase A (PKA) and Ca2+/calmodulin-dependent protein kinase II (CaMKII)-dependent protein phosphorylation, which are required for the generat
Autor:
Syevda Tagirova Sirenko, Edward G. Lakatta, Christopher H. Morrell, Alexey E. Lyashkov, Dongmei Yang, Yael Yaniv, Victor A. Maltsev, Tatiana M. Vinogradova, Ihor Zahanich, Bruce D. Ziman
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology, Vol 12 (2021)
Ca2+ and Vm transitions occurring throughout action potential (AP) cycles in sinoatrial nodal (SAN) cells are cues that (1) not only regulate activation states of molecules operating within criticality (Ca2+ domain) and limit-cycle (Vm domain) mechan
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8414, p 8414 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The sinoatrial (SA) node is the physiological pacemaker of the heart, and resting heart rate in humans is a well-known risk factor for cardiovascular disease and mortality. Consequently, the mechanisms of initiating and regulating the normal spontane
Autor:
Edward G. Lakatta, Daniel R. Riordon, Tatiana M. Vinogradova, Kirill V. Tarasov, Yelena S. Tarasova
Publikováno v:
European Heart Journal. 41
The spontaneous beating rate of rabbit sinoatrial node cells (SANC) is regulated by local subsarcolemmal calcium releases (LCRs) from sarcoplasmic reticulum (SR). LCRs appear during diastolic depolarization (DD) and activate an inward sodium/calcium