Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Tatiana L. Steiler"'
Autor:
Fumio Sakane, Yun Chau Long, Juleen R. Zierath, Olga Kotova, Anna Krook, Markku Laakso, Marie Björnholm, Carolina Nylén, Jianjun Wang, Marc Gilbert, Tatiana L. Steiler, Matthew K. Topham, Ying Leng, Harriet Wallberg-Henriksson, Zhihui Zhong, Alexander V. Chibalin, Elaine Vieira
Publikováno v:
Cell. 132:375-386
Type 2 (non-insulin-dependent) diabetes mellitus is a progressive metabolic disorder arising from genetic and environmental factors that impair beta cell function and insulin action in peripheral tissues. We identified reduced diacylglycerol kinase d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4b0f9f5375425a7914e95d0a127844
https://doi.org/10.1016/j.cell.2007.12.035
https://doi.org/10.1016/j.cell.2007.12.035
Autor:
Dana Galuska, Hui Gao, Karin Dahlman-Wright, Suad Efendic, Jan-Åke Gustafsson, Tatiana L. Steiler, Stefan Nilsson, Akhtar Khan, Juleen R. Zierath, Galyna Bryzgalova, Bo Ahrén
Publikováno v:
Diabetologia. 49:588-597
We used oestrogen receptor-alpha (ERalpha) knockout (ERKO) and receptor-beta (ERbeta) knockout (BERKO) mice to investigate the mechanism(s) behind the effects of oestrogens on glucose homeostasis.Endogenous glucose production (EGP) was measured in ER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ab6b98daf61fc3b4455e1a9d2d890c
https://doi.org/10.1007/s00125-005-0105-3
https://doi.org/10.1007/s00125-005-0105-3
Autor:
Dana Galuska, Brian R. Barnes, Yun Chau Long, Tatiana L. Steiler, Ying Leng, Leif Andersson, Juleen R. Zierath, Jørgen F. P. Wojtaszewski
Publikováno v:
Diabetes. 54:3484-3489
5′-AMP–activated protein kinase (AMPK) is important for metabolic sensing. We used AMPKγ3 mutant–overexpressing Tg-Prkag3 225Q and AMPKγ3-knockout Prkag3 −/− mice to determine the role of the AMPKγ3 isoform in exercise-induced metabolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51dd0c90891ba452e3753117c6741007
https://doi.org/10.2337/diabetes.54.12.3484
https://doi.org/10.2337/diabetes.54.12.3484
Autor:
Tatiana L. Steiler, Margit Mahlapuu, Leif Andersson, Juleen R. Zierath, Yun Chau Long, Sofia Martinsson, Brian R. Barnes, Ying Leng, Harriet Wallberg-Henriksson
Publikováno v:
Diabetologia. 48:2354-2364
AMP-activated protein kinase (AMPK) regulates metabolic adaptations in skeletal muscle. The aim of this study was to investigate whether AMPK modulates the expression of skeletal muscle genes that have been implicated in lipid and glucose metabolism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efbc5a618ea7c0f0290c2151ea46ca06
https://doi.org/10.1007/s00125-005-1962-5
https://doi.org/10.1007/s00125-005-1962-5
Autor:
Göran Hjälm, Leif Andersson, Carina Johansson, Margit Mahlapuu, Tatiana L. Steiler, Valérie Amarger, Juleen R. Zierath, Brian R. Barnes, Dana Galuska, Ying Leng, Stefan L. Marklund, Mark R. Walter, Magnus Åbrink, Kerstin Lindgren, David Stapleton
Publikováno v:
Journal of Biological Chemistry. 279:38441-38447
5'-AMP-activated protein kinase (AMPK) is a metabolic stress sensor present in all eukaryotes. A dominant missense mutation (R225Q) in pig PRKAG3, encoding the muscle-specific gamma3 isoform, causes a marked increase in glycogen content. To determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c68027d281bf8a51b1a58c944804f748
https://doi.org/10.1074/jbc.m405533200
https://doi.org/10.1074/jbc.m405533200
Publikováno v:
Diabetes. 53(6)
Effects of diverse stimuli, including insulin, muscle contraction, and phorbol 12-myristate-13-acetate (PMA), were determined on phosphorylation of mitogen-activated protein kinase (MAPK) signaling modules (c-Jun NH2-terminal kinase [JNK], p38 MAPK,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc7c20392c6d359998bff4004a4f4b2
https://pubmed.ncbi.nlm.nih.gov/15161746
https://pubmed.ncbi.nlm.nih.gov/15161746
Autor:
Dana Galuska, Ying Leng, Marc Gilbert, Juleen R. Zierath, Tatiana L. Steiler, Alexander V. Chibalin
Publikováno v:
Endocrinology. 144(12)
We determined basal and insulin-stimulated responses on signaling intermediates in soleus skeletal muscle from male Wistar and diabetic Goto-Kakizaki (GK) rats. Rats were infused with glucose (5 or 20 mm) for 3 h, followed by a continuous infusion of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9841d0566c2d2be642c0b213cfb228e2
https://pubmed.ncbi.nlm.nih.gov/12960081
https://pubmed.ncbi.nlm.nih.gov/12960081
Autor:
Lee G.D. Fryer, David Carling, Brian R. Barnes, Juleen R. Zierath, Jeffrey W. Ryder, Tatiana L. Steiler
Publikováno v:
Diabetes. 51(9)
Glucose transport can be activated in skeletal muscle in response to insulin via activation of phosphoinositide (PI) 3-kinase and in response to contractions or hypoxia, presumably via activation of 5' AMP-activated protein kinase (AMPK). We determin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2132db8eb6fda0c1dba6339418749a14
https://pubmed.ncbi.nlm.nih.gov/12196462
https://pubmed.ncbi.nlm.nih.gov/12196462