Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Tatiana I. Netzeva"'
Publikováno v:
Chemical Research in Toxicology. 21:911-927
A mechanistically based quantitative structure-activity relationship (QSAR) for the uncoupling activity of weak organic acids has been derived. The analysis of earlier experimental studies suggested that the limiting step in the uncoupling process is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a92d9a68754853efd53b18052b2e86
https://doi.org/10.1021/tx700391f
https://doi.org/10.1021/tx700391f
Publikováno v:
QSAR & Combinatorial Science. 27:41-48
This paper is based on an in-depth review performed by the European Chemicals Bureau of the European Commission's Joint Research Centre in support of the development of technical guidance for the implementation of the Registration, Evaluation, Author
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::095da21b0d8c3ef6dc7e393d022574d3
https://doi.org/10.1002/qsar.200710107
https://doi.org/10.1002/qsar.200710107
Publikováno v:
QSAR & Combinatorial Science. 27:77-90
This paper reviews Quantitative Structure-Activity Relationship (QSAR) models for acute mammalian toxicity published in the last decade. A number of QSAR models based on cytotoxicity data from mammalian cell lines are also included because of their p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0fa79c45ea2c2fbfe24399a67fd01ad
https://doi.org/10.1002/qsar.200710099
https://doi.org/10.1002/qsar.200710099
Publikováno v:
QSAR & Combinatorial Science. 27:21-31
This paper reviews the state of the art of in silico methods for assessing the tendency of a substance to bioconcentrate in aquatic organisms usually expressed as its Bioconcentration Factor (BCF). It is based on an in-depth review performed by the E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::168cd3001c58a09621086124b6deb927
https://doi.org/10.1002/qsar.200710102
https://doi.org/10.1002/qsar.200710102
Publikováno v:
QSAR & Combinatorial Science. 26:238-254
There are many issues relating to the use of Quantitative Structure–Activity Relationships (QSARs) to make predictions for regulatory purposes. Among those issues, characterization of models and the development of suitable tools to determine applic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a930ead5e1a9c62d1053d797a21a4a40
https://doi.org/10.1002/qsar.200630020
https://doi.org/10.1002/qsar.200630020
Autor:
T. Wayne Schultz, Tatiana I. Netzeva
Publikováno v:
Chemosphere. 61:1632-1643
The aim of the study was to develop quantitative structure–activity relationships (QSARs) for a large group of 77 aromatic aldehydes tested for acute toxicity to the ciliate Tetrahymena pyriformis using mechanistically interpretable descriptors. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68cded64679b715ec473661a287d98fb
https://doi.org/10.1016/j.chemosphere.2005.04.040
https://doi.org/10.1016/j.chemosphere.2005.04.040
Autor:
Romualdo Benigni, Tatiana I. Netzeva, Gilman Veith, Terry W Schultz, Roger Perkins, Gilles Klopman, Johannes J.M. van de Sandt, Nina Nikolova-Jeliazkova, Andrew Worth, Joanna Jaworska, David W. Roberts, Mark T. D. Cronin, Glenn J. Myatt, Carol A. Marchant, Chihae Yang, Weida Tong, Paola Gramatica, Tom Aldenberg, Scott Kahn, Grace Patlewicz, David T. Stanton
Publikováno v:
Alternatives to Laboratory Animals. 33:155-173
This is the 52nd report of a series of workshops organised by the European Centre for the Validation of Alternative Methods (ECVAM). The main objective of ECVAM, as defined in 1993 by its Scientific Advisory Committee, is to promote the scientific an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2146edd395bd8d7dd7b816fec78b6076
https://doi.org/10.1177/026119290503300209
https://doi.org/10.1177/026119290503300209
Autor:
A P Wortha, S Jeram, B Sokull-Klüttgen, Tatiana I. Netzeva, Mark T. D. Cronin, Iglika Lessigiarska, John C. Dearden
Publikováno v:
SAR and QSAR in Environmental Research. 15:413-431
A large data set containing values for fish, algae and Daphnia toxicity for more than 2000 chemicals and mixtures was investigated. The data set was taken from the New Chemicals Data Base of the European Union [hosted by the European Chemicals Bureau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c78aa9e6eb54dd01fcaa5f6fb72f21d
https://doi.org/10.1080/10629360412331297416
https://doi.org/10.1080/10629360412331297416
Autor:
T. Wayne Schultz, Judith C. Duffy, Gerrit Schüürmann, Shaqil H. Chaudary, Tatiana I. Netzeva, Mark T. D. Cronin, Aynur O. Aptula
Publikováno v:
QSAR & Combinatorial Science. 22:575-582
The aim of this study was to develop quantitative structure-activity relationships for the toxicity to Tetrahymena pyriformis of 30 substituted poly-hydroxylated benzenes. Physico-chemical descriptors for the expression of free radical formation, ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7550a937968c019a786cadd53b7fa300
https://doi.org/10.1002/qsar.200330816
https://doi.org/10.1002/qsar.200330816
Publikováno v:
SAR and QSAR in Environmental Research. 14:265-283
The aim of this study was to evaluate a multivariate statistical model, utilising Partial Least Squares (PLS) analysis, for the prediction of the acute toxicity of aliphatic chemicals to the ciliate Tetrahymena pyriformis. A model was developed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dba297ed76a46d816d1283759ab708f
https://doi.org/10.1080/1062936032000101501
https://doi.org/10.1080/1062936032000101501