Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tatiana I. Leakey"'
Autor:
John E. Seng, Tatiana I. Leakey, Beth E. Juliar, Heidi L. Badgley, Sherry M. Lewis, Amy Babb, Ralph E. Patton, Julian E.A. Leakey, Kelly Davis, A Afshan Ali
Publikováno v:
Toxicology and applied pharmacology. 412
D -glucosamine is a widely consumed dietary supplement used to promote joint health and treat osteoarthritis. It also stimulates intracellular hexosamine flux and increases transforming growth factor β1 (TGFβ1) mRNA expression and insulin resistanc
Autor:
Tatiana I. Leakey, Fariba Jousheghany, Aiwei Yao-Borengasser, Eric R. Siegel, Behjatolah Monzavi-Karbassi, Craig A. Cooney, Damir Herman, Alice Behrens, A. Mazin Safar, Soheila Korourian, Bounleut Phanavanh, Thomas Kieber-Emmons
Publikováno v:
International Journal of Oncology
Our previously published data link P-selectin-reactive chondroitin sulfate structures on the surface of breast cancer cells to metastatic behavior of cells. We have shown that a particular sulfation pattern mediated by the expression of carbohydrate
Autor:
William T. Allaben, Nalini Agrawal, John E. Seng, Tatiana I. Leakey, Shijun Xia, Elizabeth T.M. Horsley, Erin M. Scherer, Julian E.A. Leakey
Publikováno v:
Toxicology and Applied Pharmacology. 193:281-292
Chloral hydrate is widely used as a sedative in pediatric medicine and is a by-product of water chlorination and a metabolic intermediate in the biotransformation of trichloroethylene. Chloral hydrate and its major metabolite, trichloroacetic acid, i
Autor:
Craig A. Cooney, Tonya M. Rafferty, Colin Larson, Tatiana I. Leakey, Thomas E. Johnson, Chris Downing, Rachel N. Siegfried
Publikováno v:
Alcohol (Fayetteville, N.Y.). 45(1)
C57BL/6J (B6) mice are susceptible to in utero growth retardation and a number of morphological malformations following prenatal alcohol exposure, while DBA/2J (D2) mice are relatively resistant. We have previously shown that genomic imprinting may p
Autor:
Tatiana I. Leakey, Jerzy Zielinski, Eric R. Siegel, Chun-Yang Fan, Rachel N. Siegfried, Craig A. Cooney
Publikováno v:
Nucleic Acids Research
DNA methylation at cytosines is a widely studied epigenetic modification. Methylation is commonly detected using bisulfite modification of DNA followed by PCR and additional techniques such as restriction digestion or sequencing. These additional tec
Autor:
Damir Herman, Behjatolah Monzavi-Karbassi, Aiwei Yao-Borengasser, Fariba Jousheghany, Tatiana I. Leakey, Craig A. Cooney, Thomas Kieber-Emmons
Publikováno v:
Cancer Research. 72:4018-4018
Introduction: We have previously demonstrated that chondroitin sulfates (CS) play a crucial role in metastatic potential of breast cancer cells. We have shown that the expression level of carbohydrate (chondroitin 4) sulfotransferase-11 (CHST11) corr