Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tatiana I, Novobrantseva"'
Autor:
Vera M Ruda, Rohit Chandwani, Alfica Sehgal, Roman L Bogorad, Akin Akinc, Klaus Charisse, Alexander Tarakhovsky, Tatiana I Novobrantseva, Victor Koteliansky
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101749 (2014)
Argonaute 2 (Ago2) is the only mammalian Ago protein capable of mRNA cleavage. It has been reported that the activity of the short interfering RNA targeting coding sequence (CDS), but not 3' untranslated region (3'UTR) of an mRNA, is solely dependent
Externí odkaz:
https://doaj.org/article/944eb249cdc14faba263d18f526c0dbb
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Effective clinical application of antiviral immunotherapies necessitates enhancing the functional state of natural killer (NK) and CD8+ T cells. An important mechanism for the establishment of viral persistence in the liver is the activation of the P
Externí odkaz:
https://doaj.org/article/db6436d95ee54759b863098409f2d45e
Autor:
Tatiana I Novobrantseva, Anna Borodovsky, Jamie Wong, Boris Klebanov, Mohammad Zafari, Kristina Yucius, William Querbes, Pei Ge, Vera M Ruda, Stuart Milstein, Lauren Speciner, Rick Duncan, Scott Barros, Genc Basha, Pieter Cullis, Akin Akinc, Jessica S Donahoe, K Narayanannair Jayaprakash, Muthusamy Jayaraman, Roman L Bogorad, Kevin Love, Katie Whitehead, Chris Levins, Muthiah Manoharan, Filip K Swirski, Ralph Weissleder, Robert Langer, Daniel G Anderson, Antonin de Fougerolles, Matthias Nahrendorf, Victor Koteliansky
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
Leukocytes are central regulators of inflammation and the target cells of therapies for key diseases, including autoimmune, cardiovascular, and malignant disorders. Efficient in vivo delivery of small interfering RNA (siRNA) to immune cells could thu
Externí odkaz:
https://doaj.org/article/31889f2554494de9a6c937025cd1946a
Autor:
Shiri Weinstein, Rafi Emmanuel, Ashley M Jacobi, Avigdor Abraham, Mark A Behlke, Andrew G Sprague, Tatiana I Novobrantseva, Arnon Nagler, Dan Peer
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43343 (2012)
Mantle cell lymphoma is characterized by a genetic translocation results in aberrant overexpression of the CCND1 gene, which encodes cyclin D1. This protein functions as a regulator of the cell cycle progression, hence is considered to play an import
Externí odkaz:
https://doaj.org/article/e9ae1dcc0b94471fb49278df650ba05d
Publikováno v:
Current opinion in drug discoverydevelopment. 11(2)
The number of small interfering RNA (siRNA)-based therapeutics that are in or nearing human clinical trials is rapidly expanding. This review summarizes recent in vivo data obtained from studies on siRNA therapeutics and gives an overview of the key
Autor:
Susanne Ø, Andreasen, Allan R, Thomsen, Victor E, Koteliansky, Tatiana I, Novobrantseva, Andrew G, Sprague, Antonin R, de Fougerolles, Jan P, Christensen
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 171(6)
Adhesive interactions are crucial to cell migration into inflammatory sites. Using murine lymphocytic choriomeningitis virus as an Ag model system, we have investigated expression and function of collagen-binding integrins, alpha(1)beta(1) and alpha(