Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Tatiana Gudasheva"'
Autor:
Aleksey Tarasiuk, Tatiana Gudasheva, Armen Mezhlumyan, Polina Povarnina, Nellya Sazonova, Anna Tallerova, Sergey Seredenin
Publikováno v:
Pharmaceuticals; Volume 15; Issue 3; Pages: 284
Neurotrophins are considered as an attractive target for the development of antidepressants with a novel mechanism of action. Previously, the dimeric dipeptide mimetics of individual loops of nerve growth factor, NGF (GK-6, loop 1; GK-2, loop 4) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5792e1d623b649cc058e02bdbcba2820
Autor:
Tatiana Gudasheva
Publikováno v:
Acta Naturae. 10:81-84
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f1999c844290a4e813bdb68e5a317d0
https://doi.org/10.32607/20758251-2018-10-3-81-84
https://doi.org/10.32607/20758251-2018-10-3-81-84
[PHARMACOLOGICAL STUDY OF NEW COMPOUNDS ACTING AS REGULATORS OF 18-KDA TRANSLOCATOR PROTEIN LIGANDS]
Publikováno v:
Europe PubMed Central
The interaction of new original 1-arylpyrrolo[1,2-a]pyrazine-3-carboxamide derivatives with mitochondrial translocator protein (MTP) 18 kDa has been studied by radioligand binding assay. Compounds GML-1 (Ki = 5.2 x 10⁻⁸ M) and GML-3 (Ki = 5.3 x 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6355ac1b4c0e23e7f0bc5db8385efa2e
https://pubmed.ncbi.nlm.nih.gov/27159950
https://pubmed.ncbi.nlm.nih.gov/27159950
Autor:
Lg, Kolik, Vp, Zherdev, Ss, Boiko, Ma, Konstantinopol Skii, Sy, Raskin, Tatiana Gudasheva, Va, Mart Yanov, Sb, Seredenin
Publikováno v:
Europe PubMed Central
Pharmacokinetics and pharmacological activity of GB-115 dipeptide anxiolytic after oral administration in the form of crystalline and micronized substances was studied in albino male rats. In contrast to crystalline, the micronized substance exhibite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6f19e9a45208af8349434f39eb343b5f
https://pubmed.ncbi.nlm.nih.gov/27017703
https://pubmed.ncbi.nlm.nih.gov/27017703
Autor:
Tatiana Gudasheva, Ga, Romanova, Fm, Shakova, So, Kotel Nikova, Iv, Barskov, Ev, Stel Mashuk, Sb, Seredenin
Publikováno v:
Europe PubMed Central
Neuroprotective and antiamnesic effects of human nerve growth factor (HNGF) synthetic dipeptide mimetic bis-(N-monosuccinyl-glycyl-lysine)hexamethylenediamide (GK-2h) has been studied on a model of bilateral photochemically induced focal ischemical b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4e6e0fa99ab9f097518cbde00a064bd3
https://pubmed.ncbi.nlm.nih.gov/23240153
https://pubmed.ncbi.nlm.nih.gov/23240153
Autor:
Sa, Kryzhanovskiĭ, Vn, Stoliarchuk, Mb, Vititnova, Ib, Tsorin, Es, Pekel Dina, Tatiana Gudasheva
Publikováno v:
Europe PubMed Central
In experiments on anesthetized rats were assessed antifibrillatoty action of dipeptide GK-1. This compound is the fragment of fourth loop of nerve growth factor (NGF) and manifests antagonistic activity in respect to TrkA receptor, that specified for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1a25c1fbf079df53505574057400e5d9
https://pubmed.ncbi.nlm.nih.gov/23101372
https://pubmed.ncbi.nlm.nih.gov/23101372
Publikováno v:
Europe PubMed Central
Tridecapeptide neurotensin (NT) is known to exert the neuroleptic-like effects in case of its intracerebral administration. The group of systemically active dipeptides , acylprolyltyrosines, was constructed on the background of NT. Methyl ester of N-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c2609c070b4ac402763cffc0c63feb08
https://pubmed.ncbi.nlm.nih.gov/22792715
https://pubmed.ncbi.nlm.nih.gov/22792715
Publikováno v:
Europe PubMed Central
The effects of GB-115 dipeptide, a retroanalog of endogenous CCK-4, on the behavioral indices in "elevated plus maze" (EPM) test and on the content of biogenic amines in the brain structures after discontinuation of a chronic administration of benzod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::42de4c5213eb4bf1cef3b60a057379f6
https://pubmed.ncbi.nlm.nih.gov/22238979
https://pubmed.ncbi.nlm.nih.gov/22238979
Autor:
Lg, Kolik, Tl, Garibova, Sa, Litvinova, Al, Kuznetsova, Ig, Kapitsa, Ia, Kadnikov, Ma, Konstantinopol Skiĭ, Tatiana Gudasheva, Ta, Voronina, Sb, Seredenin
Publikováno v:
Europe PubMed Central
Effects of GB-115, an anxiolytic L-triptophan-containing dipeptide, based on the endogenous tetrapeptide cholecystokinin, were evaluated during and after withdrawal of its long-term administration to rats in comparison with diazepam. It was shown usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ffe89b6eca8e810d7830a0a913f2a396
https://pubmed.ncbi.nlm.nih.gov/21899090
https://pubmed.ncbi.nlm.nih.gov/21899090
Publikováno v:
Europe PubMed Central
The influence of dilept (GZR-123, N-caproyl-L-prolyl-L-tyrosine methyl ester)--a dipeptide analog of neurotensin (NT)--on extracellular concentration of glutamate, gamma-aminobutyric acid (GABA) and homovanillic acid (HVA) in n. accumbens of Wistar r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a686b865e62ed8b4a13c46c281dafcb0
https://pubmed.ncbi.nlm.nih.gov/21395009
https://pubmed.ncbi.nlm.nih.gov/21395009