Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Tatiana E Erova"'
Autor:
Tatiana E Erova, Michelle L Kirtley, Erc C Fitts, Duraisamy Ponnusamy, Wallace B Baze, Jourdan A Andersson, Yingzi Cong, Bethany L Tiner, Jian Sha, Ashok K Chopra
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 6 (2016)
We evaluated the extent of attenuation and immunogenicity of the ∆lppAB and ∆lppAB ∆msbB mutants of Salmonella enterica serovar Typhimurium when delivered to mice by the oral route. These mutants were deleted either for the Braun lipoprotein ge
Externí odkaz:
https://doaj.org/article/d8a91f8e569d44269027cadadf724fb6
Autor:
Eric C. Fitts, Jourdan A. Andersson, Michelle L. Kirtley, Jian Sha, Tatiana E. Erova, Sadhana Chauhan, Vladimir L. Motin, Ashok K. Chopra
Publikováno v:
mSphere, Vol 1, Iss 6 (2016)
ABSTRACT The Enterobacteriaceae family members, including the infamous Yersinia pestis, the causative agent of plague, have a highly conserved interbacterial signaling system that is mediated by the autoinducer-2 (AI-2) quorum-sensing molecule. The A
Externí odkaz:
https://doaj.org/article/f5e9bf8105cc43fc899d565a281323ec
Autor:
Vladimir L. Motin, Bethany L. Tiner, Elena V. Kozlova, Snehal S. Patel, Jian Sha, Jennifer E. Peel, Michelle L. Kirtley, William S Lawrence, Ashok K. Chopra, Satheesh K Sivasubramani, Johnny W. Peterson, Igor Patrikeev, Tatiana E. Erova, Jourdan A. Andersson, Duraisamy Ponnusamy, David McWilliams, Wallace B. Baze, Curtis Klages, Eric C. Fitts, Maxim V. Telepnev, Eric Rothe
Publikováno v:
Clinical and Vaccine Immunology. 23:586-600
Currently, no plague vaccine exists in the United States for human use. The capsular antigen (Caf1 or F1) and two type 3 secretion system (T3SS) components, the low-calcium-response V antigen (LcrV) and the needle protein YscF, represent protective a
Autor:
Vsevolod L. Popov, Ashok K. Chopra, Jian Sha, Tatiana E. Erova, Wallace B. Baze, Duraisamy Ponnusamy, Eric C. Fitts, Christina J. van Lier, Bethany L. Tiner
Publikováno v:
Clinical and Vaccine Immunology. 22:1255-1268
Earlier, we showed that the ΔlppΔmsbBΔailtriple mutant ofYersinia pestisCO92 with deleted genes encoding Braun lipoprotein (Lpp), an acyltransferase (MsbB), and the attachment invasion locus (Ail), respectively, was avirulent in a mouse model of p
Autor:
Tatiana E. Erova, Michelle L. Kirtley, Duraisamy Ponnusamy, Elena V. Kozlova, Eric C. Fitts, Ashok K. Chopra, Bethany L. Tiner, Jian Sha, Jourdan A. Andersson
Publikováno v:
Infection and Immunity. 83:2065-2081
The identification of new virulence factors in Yersinia pestis and understanding their molecular mechanisms during an infection process are necessary in designing a better vaccine or to formulate an appropriate therapeutic intervention. By using a hi
Autor:
Jourdan A. Andersson, Jian Sha, Tatiana E. Erova, Eric C. Fitts, Duraisamy Ponnusamy, Elena V. Kozlova, Michelle L. Kirtley, Ashok K. Chopra
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Earlier, we reported the identification of new virulence factors/mechanisms of Yersinia pestis using an in vivo signature-tagged mutagenesis (STM) screening approach. From this screen, the role of rbsA, which encodes an ATP-binding protein of ribose
Autor:
Yingzi Cong, Michelle L. Kirtley, Jian Sha, Bethany L. Tiner, Anthony T. Cao, Vsevolod L. Popov, Tatiana E. Erova, Christina J. van Lier, Ashok K. Chopra, Wallace B. Baze, Elena V. Kozlova
Publikováno v:
Infection and Immunity. 82:2485-2503
Currently, there is no FDA-approved vaccine against Yersinia pestis , the causative agent of bubonic and pneumonic plague. Since both humoral immunity and cell-mediated immunity are essential in providing the host with protection against plague, we d
Autor:
Michelle L. Kirtley, Christina J. van Lier, Jason A. Rosenzweig, Elena V. Kozlova, Ashok K. Chopra, Abidat Lawal, Tatiana E. Erova, Jian Sha
Publikováno v:
Astrobiology. 13:821-832
Previously, we reported that there was no enhancement in the virulence potential (as measured by cell culture infections) of the bacterial pathogen Yersinia pestis (YP) following modeled microgravity/clinorotation growth. We have now further characte
Autor:
Tatiana E. Erova, Jason A. Rosenzweig, Michelle L. Kirtley, Eric C. Fitts, Christina J. van Lier, Elena V. Kozlova, Jian Sha, Ashok K. Chopra, Bethany L. Tiner
Publikováno v:
Microbial Pathogenesis. 55:39-50
The gold standard in microbiology for monitoring bacterial dissemination in infected animals has always been viable plate counts. This method, despite being quantitative, requires sacrificing the infected animals. Recently, however, an alternative me
Autor:
Maxim V. Telepnev, Christina J. van Lier, Tatiana E. Erova, Ashok K. Chopra, Giovanni Suarez, Michelle L. Kirtley, Jian Sha, Jason A. Rosenzweig, Johanna C. Sierra, Vladimir L. Motin
Publikováno v:
Clinical and Vaccine Immunology. 20:227-238
Plague caused by Yersinia pestis manifests itself in bubonic, septicemic, and pneumonic forms. Although the U.S. Food and Drug Administration recently approved levofloxacin, there is no approved human vaccine against plague. The capsular antigen F1 a