Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Tatiana Domitrovic"'
Autor:
Otávio Augusto Leitão Dos Santos, Rodolfo L. Carneiro, Rodrigo D. Requião, Marcelo Ribeiro-Alves, Tatiana Domitrovic, Fernando L. Palhano
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract During protein synthesis, organisms detect translation defects that induce ribosome stalling and result in protein aggregation. The Ribosome-associated Quality Control (RQC) complex, comprising TCF25, LTN1, and NEMF, is responsible for ident
Externí odkaz:
https://doaj.org/article/5283165e22dd4ec78e3d19d2bd07fc72
Autor:
Roger Castells-Graells, Jonas R. S. Ribeiro, Tatiana Domitrovic, Emma L. Hesketh, Charlotte A. Scarff, John E. Johnson, Neil A. Ranson, David M. Lawson, George P. Lomonossoff
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Castells-Graells et al. demonstrate the maturation of insect virus Nudaurelia capensis omega virus (NωV) capsids in a plant model. This shows plants are a useful tool in the study of eukaryotic viruses across Kingdoms, and they identify new features
Externí odkaz:
https://doaj.org/article/8e17ddb56f504029911eedd8efcedc8f
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 6255-6262 (2021)
Defensins are small proteins, usually ranging from 3 to 6 kDa, amphipathic, disulfide-rich, and with a small or even absent hydrophobic core. Since a hydrophobic core is generally found in globular proteins that fold in an aqueous solvent, the peculi
Externí odkaz:
https://doaj.org/article/364db1b553094418b55135f39f28ed16
Autor:
Jan-Philip Merkl, Malak Safi, Christian Schmidtke, Fadi Aldeek, Johannes Ostermann, Tatiana Domitrovic, Sebastian Gärtner, John E. Johnson, Horst Weller, Hedi Mattoussi
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 10, Iss 1, Pp 2477-2482 (2019)
In this letter, we report on the ability of functional fusion proteins presenting a lytic gamma peptide, to promote interactions with HeLa cells and delivery of large hybrid nanostructures.
Externí odkaz:
https://doaj.org/article/b520b9a2a8fa40489d30c7564ad9fb33
Autor:
Rodrigo D Requião, Luiza Fernandes, Henrique José Araujo de Souza, Silvana Rossetto, Tatiana Domitrovic, Fernando L Palhano
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 5, p e1005549 (2017)
As proteins are synthesized, the nascent polypeptide must pass through a negatively charged exit tunnel. During this stage, positively charged stretches can interact with the ribosome walls and slow the translation. Therefore, charged polypeptides ma
Externí odkaz:
https://doaj.org/article/e36b374260774d9d93e997c346067ad7
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136761 (2015)
Pyridoxinamine 5'-phosphate oxidases (P(N/M)P oxidases) that bind flavin mononucleotide (FMN) and oxidize pyridoxine 5'-phosphate or pyridoxamine 5'-phosphate to form pyridoxal 5'-phosphate (PLP) are an important class of enzymes that play a central
Externí odkaz:
https://doaj.org/article/c45f960b4ca6442cb9b735918ebac440
Autor:
Tatiana Domitrovic, Guennadi Kozlov, João Claudio Gonçalves Freire, Claudio Akio Masuda, Marcius da Silva Almeida, Mónica Montero-Lomeli, Georgia Correa Atella, Edna Matta-Camacho, Kalle Gehring, Eleonora Kurtenbach
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11163 (2010)
The genome of Saccharomyces cerevisiae is arguably the best studied eukaryotic genome, and yet, it contains approximately 1000 genes that are still relatively uncharacterized. As the majority of these ORFs have no homologs with characterized sequence
Externí odkaz:
https://doaj.org/article/c5b8cf9dc65a48058925a8b9d9f949b0
Publikováno v:
Genetics and Molecular Biology, Iss 0
Abstract Regulation of protein stability and/or degradation of misfolded and damaged proteins are essential cellular processes. A part of this regulation is mediated by the so-called N-end rule proteolytic pathway, which, in concert with the ubiquiti
Externí odkaz:
https://doaj.org/article/7e5fa318d51843abb87a2cd790265dd7
Autor:
Otávio Augusto Leitão Dos Santos, Rodolfo L. Carneiro, Rodrigo D. Requião, Marcelo Ribeiro-Alves, Tatiana Domitrovic, Fernando L. Palhano
During protein synthesis, organisms constantly survey defective translation events that may lead to ribosome stalling with consequent ribosome collisions. Translation problems can result in misfolded protein products that sequester ribosomes into int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49be1a8ea2b5969ce8cf8249d797e368
https://doi.org/10.1101/2023.02.06.527332
https://doi.org/10.1101/2023.02.06.527332
Autor:
Charlotte A. Scarff, Jonas R S Ribeiro, John E. Johnson, Roger Castells-Graells, George P. Lomonossoff, Tatiana Domitrovic, David M. Lawson, Neil A. Ranson, Emma L. Hesketh
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Communications biology, vol 4, iss 1
Communications Biology
Communications biology, vol 4, iss 1
Communications Biology
Many virus capsids undergo exquisitely choreographed maturation processes in their host cells to produce infectious virions, and these remain poorly understood. As a tool for studying virus maturation, we transiently expressed the capsid protein of t