Výsledky vyhledávání - "Tatiana A. Laidus"

Changes in the concentration of EGFR-mutated plasma DNA in the first hours of targeted therapy allow the prediction of tumor response in patients with EGFR-driven lung cancer

Autor: Fedor V. Moiseyenko, Ekaterina S. Kuligina, Albina S. Zhabina, Sergey A. Belukhin, Tatiana A. Laidus, Aleksandr S. Martianov, Kirill A. Zagorodnev, Tatyana N. Sokolova, Svetlana A. Chuinyshena, Maxim M. Kholmatov, Elizaveta V. Artemieva, Ekaterina O. Stepanova, Tatiana N. Shuginova, Nikita M. Volkov, Grigoriy A. Yanus, Evgeny N. Imyanitov

Publikováno v: International Journal of Clinical Oncology. 27:850-862

This study aimed to analyze changes in the plasma concentration of EGFR-mutated circulating tumor DNA (ctDNA) occurring immediately after the start of therapy with EGFR tyrosine kinase inhibitors (TKIs).Serial plasma samples were collected from 30 pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d21b13e5dd11b55a0a8eb9b2ba6a39
https://doi.org/10.1007/s10147-022-02128-6

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Liquid biopsy as the universal DNA-based method for early cancer detection: problems, approaches, solutions

Autor: Ekaterina Sh Kuligina, Svetlana N. Aleksakhina, Grigoriy A. Yanus, Evgeny N. Imyanitov, Aleksandr S. Martianov, Tatiana A. Laidus

Publikováno v: Problems in oncology. 67:593-599

Until recently, the establishment of a universal test, allowing the early cancer detection by the analysis of blood, urine or other biological fluids seemed as realistic as the development of "Perpetuum mobile". There are numerous obstacles on this r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::757b320f339f2593edfdd97115e15278
https://doi.org/10.37469/0507-3758-2021-67-5-593-599

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Changes in the concentration of EGFR-mutated plasma DNA in the first hours of anti-EGFR therapy allow the prediction of tumor response in patients with EGFR-driven lung cancer

Autor: Tatiana A. Laidus, Tatyana N. Sokolova, Nikita M. Volkov, A S Zhabina, Maxim M. Kholmatov, Fedor Moiseenko, Ekaterina Sh Kuligina, Vladislav Turin, Aleksandr S. Martianov, Sergey Beluhin, Grigoiy Yanus

Publikováno v: Problems in oncology. 67:665-674

This study aimed to analyze changes in the plasma concentration of EGFR-mutated DNA occurring immediately after the start of therapy with EGFR tyrosine kinase inhibitors (TKIs). The study included 30 patients with EGFR mutation-driven non-small cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::30335da1ee4f7c0fcf16a0e17dd7303e
https://doi.org/10.37469/0507-3758-2021-67-5-665-674

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Content of circulating tumor DNA depends on the tumor type and the dynamics of tumor size, but is not influenced significantly by physical exercise, time of the day or recent meal

Autor: Tatyana N. Sokolova, Olga S. Yatsuk, Roman Meerovich, Kirill A. Zagorodnev, Evgeny N. Imyanitov, Maxim M. Kholmatov, Grigoriy A. Yanus, Olga A. Zaitseva, Ekaterina Sh Kuligina, Maria O. Anisimova, Tatiana A. Laidus, Aleksandr S. Martianov, Aleksandr A. Romanko

Publikováno v: Cancer Genetics. :165-178

Purpose This study aimed to investigate factors, which influence the content of circulating tumor DNA (ctDNA). Methods 398 serial plasma samples were collected within 1–7 consecutive days from patients with EGFR-mutated lung cancer (n = 13), RAS/RA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f1c5f028a7c0d994009790eb625637
https://doi.org/10.1016/j.cancergen.2021.05.014

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Preparation of Duplex Sequencing Libraries for Archival Paraffin-Embedded Tissue Samples Using Single-Strand-Specific Nuclease P1

Autor: Natalia V. Mitiushkina, Grigory A. Yanus, Ekatherina Sh. Kuligina, Tatiana A. Laidus, Alexandr A. Romanko, Maksim M. Kholmatov, Alexandr O. Ivantsov, Svetlana N. Aleksakhina, Evgeny N. Imyanitov

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4586

DNA from formalin-fixed paraffin-embedded (FFPE) tissues, which are frequently utilized in cancer research, is significantly affected by chemical degradation. It was suggested that approaches that are based on duplex sequencing can significantly impr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c36eefdcccebc7e1825f65f3d88b7b
https://pubmed.ncbi.nlm.nih.gov/35562977

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TECHNICAL ASPECTS OF LIQUID BIOPSY: INFLUENCE OF PREANALYTICAL PARAMETERS ON THE CONCENTRATION OF CIRCULATING TUMOR DNA IN PLASMA OF CANCER PATIENTS

Autor: Maxim M. Kholmatov, Tatiana A. Laidus, Grigoriy Yanus, Kirill A. Zagorodnev, T. V. Sokolova, O. Vlasova, Alexandr A. Romanko, Vladislav Tyurin, Ekatherina Sh. Kuligina, Roman Meerovich, Aleksandr Martyanov, Maria O. Anisimova

Publikováno v: Problems in oncology. 66:391-397

«Liquid biopsy» is gradually becoming a mandatory procedure in cancer diagnostics. The aim of this procedure is to detect and monitor tumor-specific markers in various body fluids (blood, urine, pleural fluid, etc.). Significant efforts have been m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::643445f6df76b56876b2d7ce63fc312d
https://doi.org/10.37469/0507-3758-2020-66-4-391-397

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Identification of recurrent pathogenic alleles using exome sequencing data: Proof-of-concept study of Russian subjects

Autor: Igor E. Orlov, Tatiana A. Laidus, Anastasia V. Tumakova, Grigoriy A. Yanus, Aglaya G. Iyevleva, Anna P. Sokolenko, Ilya V. Bizin, Evgeny N. Imyanitov, Evgeny N. Suspitsin

Publikováno v: European Journal of Medical Genetics. 65:104426

Whole exome sequencing (WES) is a powerful tool for the cataloguing of population-specific genetic diseases. Within this proof-of-concept study we evaluated whether analysis of a small number of individual exomes is capable of identifying recurrent p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b13324f8eee264c4478016bc57e61d
https://doi.org/10.1016/j.ejmg.2022.104426

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Abstract 717: Presence of distant metastases and disease progression but not tumor size, lymph node involvement, circadian rhythms, prior physical exercise or recent food consumption influence the concentration of circulating tumor DNA in cancer patients

Autor: Tatyana N. Sokolova, Tatiana A. Laidus, Ekaterina Sh Kuligina, Kirill A. Zagorodnev, Grigoriy A. Yanus, Maxim M. Kholmatov, Roman Meerovich, Evgeny N. Imyanitov, Aleksandr S. Martianov, Maria O. Anisimova

Publikováno v: Cancer Research. 80:717-717

Liquid biopsy is potentially useful for early tumor detection, monitoring of cancer disease during treatment and diagnosis of therapy-related secondary mutations. Despite significant advantages, it cannot be routinely used in cancer medicine until th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1400f29f0477890c9ea368535d4d4be6
https://doi.org/10.1158/1538-7445.am2020-717

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