Insights into the quality of recombinant proteins produced by two different Bombyx mori expression systems.

Autor: Kajiura H; International Center for Biotechnology, Osaka University, 2-1 Yamada-Oka, Suita-Shi, Osaka, 565-0871, Japan.; Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University, 2-1 Yamada-Oka, Suita-Shi, Osaka, 565-0871, Japan., Tatematsu KI; Division of Silk-Producing Insect Biotechnology, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization, 1-2 Owashi, Tsukuba, Ibaraki, 305-8634, Japan., Nomura T; Sysmex Corporation, 1548 Ooaza Shimookudomi, Sayama, Saitama, 350-1332, Japan., Miyazawa M; Division of Biomaterial Sciences, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization, 1-2 Owashi, Tsukuba, Ibaraki, 305-8634, Japan., Usami A; Sysmex Corporation, 1548 Ooaza Shimookudomi, Sayama, Saitama, 350-1332, Japan., Tamura T; Silk Science and Technology Research Institute, 1053, Iikura, Ami-Machi, Ibaraki, 300-0324, Japan., Sezutsu H; Division of Silk-Producing Insect Biotechnology, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization, 1-2 Owashi, Tsukuba, Ibaraki, 305-8634, Japan., Fujiyama K; International Center for Biotechnology, Osaka University, 2-1 Yamada-Oka, Suita-Shi, Osaka, 565-0871, Japan. fujiyama@icb.osaka-u.ac.jp.; Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University, 2-1 Yamada-Oka, Suita-Shi, Osaka, 565-0871, Japan. fujiyama@icb.osaka-u.ac.jp.; Osaka University Cooperative Research Station in Southeast Asia (OU:CRS), Faculty of Science, Mahidol University, Bangkok, Thailand. fujiyama@icb.osaka-u.ac.jp.

Publikováno v: Scientific reports [Sci Rep] 2022 Nov 02; Vol. 12 (1), pp. 18502. Date of Electronic Publication: 2022 Nov 02.

Dynamic alterations of circulating T lymphocytes and the clinical response in patients with head and neck squamous cell carcinoma treated with nivolumab.

Autor: Tada H; Department of Otolaryngology-Head and Neck Surgery, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, 3718511, Japan., Takahashi H; Department of Otolaryngology-Head and Neck Surgery, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, 3718511, Japan., Yamada K; Division of Molecular Science, Faculty of Science and Technology, Gunma University, Kiryu, Gunma, 376-8515, Japan., Masuda K; Department of Pathology, Gunma University Graduate School of Medicine, Maebashi, Gunma, 371-8511, Japan., Nagata Y; Department of Otolaryngology-Head and Neck Surgery, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, 3718511, Japan., Uchida M; Department of Otolaryngology-Head and Neck Surgery, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, 3718511, Japan., Shino M; Department of Otolaryngology-Head and Neck Surgery, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, 3718511, Japan., Ida S; Department of Otolaryngology-Head and Neck Surgery, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, 3718511, Japan., Mito I; Department of Otolaryngology-Head and Neck Surgery, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, 3718511, Japan., Matsuyama T; Department of Otolaryngology-Head and Neck Surgery, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, 3718511, Japan., Oyama T; Department of Pathology, Gunma University Graduate School of Medicine, Maebashi, Gunma, 371-8511, Japan., Tatematsu KI; Institute of Agrobiological Sciences, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, 305-8634, Japan., Sezutsu H; Institute of Agrobiological Sciences, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, 305-8634, Japan., Takeda S; Division of Molecular Science, Faculty of Science and Technology, Gunma University, Kiryu, Gunma, 376-8515, Japan., Chikamatsu K; Department of Otolaryngology-Head and Neck Surgery, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, 3718511, Japan. tikamatu@gunma-u.ac.jp.

Publikováno v: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2022 Apr; Vol. 71 (4), pp. 851-863. Date of Electronic Publication: 2021 Aug 31.

Bio-functionalized titanium surfaces with modified silk fibroin carrying titanium binding motif to enhance the ossific differentiation of MC3T3-E1.

Autor: Watanabe M; Division of Protein Engineering, Cancer Institute, Japanese Foundation for Cancer Research, Koto, Tokyo, Japan.; Department of Biotechnology, Tokyo University of Agriculture and Technology, Koganei, Tokyo, Japan., Bhawal UK; Department of Biochemistry and Molecular Biology, Research Institute of Oral Science, Nihon University School of Dentistry at Matsudo, Matsudo, Chiba, Japan., Takemoto S; Department of Biomedical Engineering, Iwate Medical University, Yahaba, Iwate, Japan., Nishiyama N; Department of Dental Biomaterials, Nihon University School of Dentistry at Matsudo, Matsudo, Chiba, Japan., Nakahara Y; Transgenic Silkworm Research Unit, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, Japan., Tatematsu KI; Transgenic Silkworm Research Unit, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, Japan., Sezutsu H; Transgenic Silkworm Research Unit, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, Japan., Kuwabara N; Gunma Sericultural Technology Center, Maebashi, Gunma, Japan., Minamisawa T; Division of Protein Engineering, Cancer Institute, Japanese Foundation for Cancer Research, Koto, Tokyo, Japan., Shiba K; Division of Protein Engineering, Cancer Institute, Japanese Foundation for Cancer Research, Koto, Tokyo, Japan., Asakura T; Department of Biotechnology, Tokyo University of Agriculture and Technology, Koganei, Tokyo, Japan.

Publikováno v: Biotechnology and bioengineering [Biotechnol Bioeng] 2021 Jul; Vol. 118 (7), pp. 2585-2596. Date of Electronic Publication: 2021 Apr 13.

Structural insight and stability of TNFR-Fc fusion protein (Etanercept) produced by using transgenic silkworms.

Autor: Kiyoshi M; Division of Biological Chemistry and Biologicals, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan., Tatematsu KI; Transgenic Silkworm Research Unit, National Institute of Agrobiological Sciences National Agriculture and Food Research Organization, 1-2 Owashi, Tsukuba, Ibaraki 305-8634, Japan., Tada M; Division of Biological Chemistry and Biologicals, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan., Sezutsu H; Transgenic Silkworm Research Unit, National Institute of Agrobiological Sciences National Agriculture and Food Research Organization, 1-2 Owashi, Tsukuba, Ibaraki 305-8634, Japan., Shibata H; Division of Biological Chemistry and Biologicals, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan., Ishii-Watabe A; Division of Biological Chemistry and Biologicals, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan.

Publikováno v: Journal of biochemistry [J Biochem] 2021 Feb 06; Vol. 169 (1), pp. 25-33.

Secretory expression of thyroid hormone receptor using transgenic silkworms and its DNA binding activity.

Autor: Nakaya H; Faculty of Science and Technology, Division of Molecular Science, Gunma University, Kiryu, Gunma, 376-8515, Japan., Tatematsu KI; Transgenic Silkworm Research Unit, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, 305-8634, Japan., Sezutsu H; Transgenic Silkworm Research Unit, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, 305-8634, Japan., Kuwabara N; Gunma Sericultural Technology Center, Maebashi, Gunma, 371-8570, Japan., Koibuchi N; Department of Integrative Physiology, Graduate School of Medicine, Gunma University, 3-39-22 Showa-machi Maebashi, Gunma, 371-8511, Japan., Takeda S; Faculty of Science and Technology, Division of Molecular Science, Gunma University, Kiryu, Gunma, 376-8515, Japan. Electronic address: stakeda@gunma-u.ac.jp.

Publikováno v: Protein expression and purification [Protein Expr Purif] 2020 Dec; Vol. 176, pp. 105723. Date of Electronic Publication: 2020 Aug 05.