Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tateki Sumii"'
Publikováno v:
Journal of Biomechanical Science and Engineering, Vol 7, Iss 2, Pp 237-247 (2012)
To date, no study has described the effects of media flow load on a co-culture model of hepatocytes (HC), hepatic stellate cells (HSC) and endothelial cells (EC). Furthermore, no research has been reported regarding the influence of nitric oxide (NO)
Externí odkaz:
https://doaj.org/article/3fbb2f5f84dd4337a9cc556815b2d8c6
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 52:625-631
Hepatic functions, such as albumin secretion and ammonia metabolism, are upregulated in response to hepatocyte growth factor (HGF) produced by hepatic stellate cells (HSC), as well as nitric oxide (NO) produced by endothelial cells under shear stress
Publikováno v:
Journal of Biorheology. 30:19-26
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 54(1)
When the liver is damaged, hepatic stellate cells (HSCs) can change into an activated, highly migratory state. The migration of HSCs may be affected by shear stress due not only to sinusoidal flow but also by the flow in the space of Disse because th
Publikováno v:
Biochemical and Biophysical Research Communications. 412:318-322
Endothelial nitric oxide synthase (eNOS) is the primary enzyme that produces nitric oxide (NO), which plays an important role in blood vessel relaxation. eNOS activation is stimulated by various mechanical forces, such as shear stress. Several studie
Autor:
Tateki Sumii, Makoto Hosobuchi, Marie Terada, Shogo Kuretoko, Tomoya Shimada, Kazuo Tanishita, Susumu Kudo
Publikováno v:
TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series B. 77:2431-2441
A phenomenon has been observed in which intracellular Ca2+ concentration in endothelial cells increases upon application of shear stress (Ca2+ response). It is therefore assumed that Ca2+ is the second messenger in the transfer of shear stress stimul
Publikováno v:
The Proceedings of Mechanical Engineering Congress, Japan. 2016:S0210105
Publikováno v:
MHS
It is necessary to develop the way how researchers culture hepatocytes (HC) for showing high levels of hepatic functions in vitro, because functions of HC in vitro is only 2-hundredth part of the functions in vivo. Hepatic function increased when HC
Publikováno v:
The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME. :191-192
Publikováno v:
The Proceedings of the JSME Conference on Frontiers in Bioengineering. :109-110