Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Tassula Proikas Cezanne"'
Autor:
Katharina Sporbeck, Maximilian L. Haas, Carmen J. Pastor-Maldonado, David S. Schüssele, Catherine Hunter, Zsuzsanna Takacs, Ana L. Diogo de Oliveira, Mirita Franz-Wachtel, Chara Charsou, Simon G. Pfisterer, Andrea Gubas, Patricia K. Haller, Roland L. Knorr, Manuel Kaulich, Boris Macek, Eeva-Liisa Eskelinen, Anne Simonsen, Tassula Proikas-Cezanne
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-23 (2023)
Abstract Human WIPI β-propellers function as PI3P effectors in autophagy, with WIPI4 and WIPI3 being able to link autophagy control by AMPK and TORC1 to the formation of autophagosomes. WIPI1, instead, assists WIPI2 in efficiently recruiting the ATG
Externí odkaz:
https://doaj.org/article/d0288956339a424480d31074800a3152
Autor:
Fulvio Reggiori, Patricia Boya, David da Costa, Zvulun Elazar, Eeva-Liisa Eskelinen, Judith Farrés, Sebastian Guettler, Claudine Kraft, Heinz Jungbluth, Ana Martinez, Etienne Morel, Ole Pless, Tassula Proikas-Cezanne, Anne Simonsen
Publikováno v:
Autophagy Reports, Vol 1, Iss 1, Pp 414-417 (2022)
This animated movie presents the mechanism of macroautophagy, hereafter autophagy, by showing the molecular features of the formation of autophagosomes, the hallmark organelle of this intracellular catabolic pathway. It is based on our current knowle
Externí odkaz:
https://doaj.org/article/e97f74e4c78e439bbf87af65db04b52c
Autor:
Dominic Gross, Helmut Bischof, Selina Maier, Katharina Sporbeck, Andreas L. Birkenfeld, Roland Malli, Peter Ruth, Tassula Proikas-Cezanne, Robert Lukowski
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-14 (2022)
Abstract Ca2+-activated K+ channels of intermediate conductance (IK) are frequently overexpressed in breast cancer (BC) cells, while IK channel depletion reduces BC cell proliferation and tumorigenesis. This raises the question, of whether and mechan
Externí odkaz:
https://doaj.org/article/36dbb1c4c62044baa46ffea7e80eab74
Autor:
Mukhran Khundadze, Federico Ribaudo, Adeela Hussain, Jan Rosentreter, Sandor Nietzsche, Melanie Thelen, Dominic Winter, Birgit Hoffmann, Muhammad Awais Afzal, Tanja Hermann, Cecilia de Heus, Eva-Maria Piskor, Christian Kosan, Patricia Franzka, Lisa von Kleist, Tobias Stauber, Judith Klumperman, Markus Damme, Tassula Proikas-Cezanne, Christian A. Hübner
Publikováno v:
Neurobiology of Disease, Vol 127, Iss , Pp 419-431 (2019)
Hereditary spastic paraplegia is a spastic gait disorder that arises from degeneration of corticospinal axons. The subtype SPG48 is associated with mutations in the zeta subunit of the adaptor protein complex five (AP5). AP5 function and the pathophy
Externí odkaz:
https://doaj.org/article/c5d0d4197e294f66a8340361edbe5c4c
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Externí odkaz:
https://doaj.org/article/8c8de52cdaf94dd3b9565aafd9792cb6
Autor:
Daniela Bakula, Amelie J. Müller, Theresia Zuleger, Zsuzsanna Takacs, Mirita Franz-Wachtel, Ann-Katrin Thost, Daniel Brigger, Mario P. Tschan, Tancred Frickey, Horst Robenek, Boris Macek, Tassula Proikas-Cezanne
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
During autophagy, AMPK and mTOR associate with ULK1 and regulate phosphatidylinositol 3-phosphate (PtdIns3P) production that mediates autophagosome formation via WIPI proteins. Here the authors show WIPI3 and WIPI4 have a scaffolding function upstrea
Externí odkaz:
https://doaj.org/article/56d33a8705964370b0a1710e530dcc35
Autor:
David S. Schüssele, Patricia K. Haller, Maximilian L. Haas, Catherine Hunter, Katharina Sporbeck, Tassula Proikas-Cezanne
Publikováno v:
Autophagy. 19:338-351
Single cell-based analysis of macroautophagy/autophagy is largely achieved through the use of fluorescence microscopy to detect autophagy-related proteins that associate with autophagic membranes and therefore can be quantified as fluorescent puncta.
Autor:
Charlotte Primard, Tassula Proikas-Cezanne, Catherine Hunter, Stavroula Zagkou, Yasmina Filali-Mouncef, Nicolas Dupont, Fulvio Reggiori, Federica Roccio
Publikováno v:
Filali-Mouncef, Y, Hunter, C, Roccio, F, Zagkou, S, Dupont, N, Primard, C, Proikas-Cezanne, T & Reggiori, F 2022, ' The ménage à trois of autophagy, lipid droplets and liver disease ', Autophagy, vol. 18, no. 1, pp. 50-72 . https://doi.org/10.1080/15548627.2021.1895658
Autophagic pathways cross with lipid homeostasis and thus provide energy and essential building blocks that are indispensable for liver functions. Energy deficiencies are compensated by breaking down lipid droplets (LDs), intracellular organelles tha
Publikováno v:
Cells, Vol 4, Iss 2, Pp 202-217 (2015)
Autophagy is a lysosomal degradation process for cytoplasmic components, including organelles, membranes, and proteins, and critically secures eukaryotic cellular homeostasis and survival. Moreover, autophagy-related (ATG) genes are considered essent
Externí odkaz:
https://doaj.org/article/ab2618a95ccf4213a85e0f391907ee8a
Autor:
Dominic, Gross, Helmut, Bischof, Selina, Maier, Katharina, Sporbeck, Andreas L, Birkenfeld, Roland, Malli, Peter, Ruth, Tassula, Proikas-Cezanne, Robert, Lukowski
Publikováno v:
Cell deathdisease. 13(10)
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